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A Paradigm Shift to Prevent and Treat Alzheimer s Disease

A Paradigm Shift to Prevent and Treat Alzheimer s Disease
  • Author : Howard Friel
  • Publsiher : Academic Press
  • Release : 18 July 2017
  • ISBN : 012812279X
  • Pages : 290 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKA Paradigm Shift to Prevent and Treat Alzheimer s Disease

Summary:
A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gallate (EGCG) from green tea, and oleocanthal and oleuropein from olive oil, in addition to a special extract, EGb 761, from the leaves of Ginkgo biloba, the oldest living species of tree on earth. This book also presents a new analytical framework that convincingly favors a multi-targeting ("pleiotropic") approach to the prevention and treatment of complex chronic diseases, in contrast to the mono-targeting of the pharmaceutical model. A Paradigm Shift to Prevent and Treat Alzheimer’s Disease is a unique and exciting resource for pharmaceutical scientists, pharmacologists, neurologists, general practitioners, research scientists in various medical and life sciences, healthcare professionals in clinical and executive positions, conventional medical schools, schools of naturopathic medicine, healthcare and medical journalists, executives in both national public healthcare systems and private insurers, and informed general readers. Presents carefully compiled evidence supporting the need to shift from pharmaceutical-based mono-targeting to plant polyphenol-based pleiotropic targeting for the prevention and treatment of Alzheimer’s disease Includes valuable tables that aggregate pleiotropic pharmacological effects of the plant polyphenols on Alzheimer’s disease-related pathogenic hallmarks Highlights regulatory aspects and discusses the challenges and potential solutions with respect to bioavailability of certain plant polyphenols


A Paradigm Shift to Prevent and Treat Alzheimer's Disease

A Paradigm Shift to Prevent and Treat Alzheimer's Disease
  • Author : Howard Friel,Sally A. Frautschy
  • Publisher : Academic Press
  • Release : 18 July 2017
GET THIS BOOKA Paradigm Shift to Prevent and Treat Alzheimer's Disease

A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gallate (EGCG) from green tea, and oleocanthal and



The End of Alzheimer's

The End of Alzheimer's
  • Author : Dale Bredesen
  • Publisher : Penguin
  • Release : 22 August 2017
GET THIS BOOKThe End of Alzheimer's

The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it




The Alzheimer Conundrum

The Alzheimer Conundrum
  • Author : Margaret Lock
  • Publisher : Princeton University Press
  • Release : 20 October 2015
GET THIS BOOKThe Alzheimer Conundrum

Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer’s disease through early detection of pre-symptomatic biological changes in healthy individuals. Based on a meticulous account of the history of Alzheimer’



Animal Experimentation

Animal Experimentation
  • Author : Kathrin Herrmann,Kimberley Jayne
  • Publisher : Human-Animal Studies
  • Release : 25 February 2021
GET THIS BOOKAnimal Experimentation

Animal Experimentation: Working Towards a Paradigm Change critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.


Alzheimer's Disease

Alzheimer's Disease
  • Author : Harald Hampel,Maria C. Carrillo
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 25 February 2021
GET THIS BOOKAlzheimer's Disease

How current biomarkers are modernizing the diagnosis of Alzheimer's disease Expanding knowledge on genetic and epigenetic risk factors is rapidly enhancing our understanding of the complex molecular interactions and systems involved in the pathogenesis of Alzheimer's disease. In this publication, leading experts discuss emerging novel conceptual models of the disease along with advances in the development of surrogate markers that will not only improve the accuracy of diagnostic technologies but also improve the prospects of developing disease-modifying interventions. The novel


The Biology of Alzheimer Disease

The Biology of Alzheimer Disease
  • Author : Dennis J. Selkoe,David Michael Holtzman,Eckhard Mandelkow
  • Publisher : Anonim
  • Release : 25 February 2021
GET THIS BOOKThe Biology of Alzheimer Disease

Alzheimer Disease represents an important area of research in neurobiology, cell biology, developmental biology and pathology. Understanding the nature of the changes that occur in neurons as the disease progresses — accumulation of amyloid beta and neurofibrillary tangles — is obviously important as we try to develop therapeutic approaches. Moreover, the normal physiological roles of proteins such as APP and tau, whose processing appears to be altered in Alzheimer Disease, is also an intense area of research.


Treating Dementia

Treating Dementia
  • Author : Jesse F. Ballenger,Peter J. Whitehouse,Constantine G. Lyketsos
  • Publisher : Anonim
  • Release : 19 October 2009
GET THIS BOOKTreating Dementia

Treatments for age-related dementia and the growing reliance on pharmaceuticals to alleviate its worst symptoms raise a number of questions about attitudes toward aging and cognition, the relationship between growing older and getting sick, and the conflicting interests of patients, caregivers, physicians, scientists, and business. This volume aims to foster a constructive debate about the future of dementia treatment by providing multiple perspectives on these tangled issues. The first section examines how the concepts of dementia have expanded to encompass


The Alzheimer's Disease Challenge

The Alzheimer's Disease Challenge
  • Author : Athanasios Alexiou,Mohammad A. Kamal,Ghulam Md Ashraf
  • Publisher : Frontiers Media SA
  • Release : 04 December 2019
GET THIS BOOKThe Alzheimer's Disease Challenge

Alzheimer’s disease is undoubtedly the major health challenge of our Century with significant social and economic consequences. This Frontiers eBook offers a contribution of 39 innovative papers on the multidimensional and crucial problem of Alzheimer’s disease management and treatment. Several perspectives, research updates, and trials describing methods on potential diagnosis and treatment are presented including biological mechanisms, biomarkers and risk factors for an early and efficient prognosis, diagnosis and prevention. Additionally, while the rapidly increasing Alzheimer’s disease population



The Tell

The Tell
  • Author : Matthew Hertenstein
  • Publisher : Basic Books
  • Release : 12 November 2013
GET THIS BOOKThe Tell

Every day we make predictions based on limited information, in business and at home. Will this company’s stock performance continue? Will the job candidate I just interviewed be a good employee? What kind of adult will my child grow up to be? We tend to dismiss our predictive minds as prone to bias and mistakes, but in The Tell, psychologist Matthew Hertenstein reveals that our intuition is surprisingly good at using small clues to make big predictions, and shows


The Best American Essays 2002

The Best American Essays 2002
  • Author : Stephen Jay Gould,Robert Atwan
  • Publisher : Houghton Mifflin Harcourt
  • Release : 25 February 2021
GET THIS BOOKThe Best American Essays 2002

Edited by the award-winning late author of The Mismeasure of Man a new collection of the finest nonfiction essays published over the past year incorporates the work of distinguished masters of the essay genre on topics ranging from pathology to the boxing arena to growing up.