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A Roadmap to Nonhematopoietic Stem Cell Based Therapeutics

A Roadmap to Nonhematopoietic Stem Cell Based Therapeutics
  • Author : Xiao-Dong Chen
  • Publsiher : Academic Press
  • Release : 31 August 2018
  • ISBN : 0128119217
  • Pages : 544 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKA Roadmap to Nonhematopoietic Stem Cell Based Therapeutics

Summary:
A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent. Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies


A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics

A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics
  • Author : Xiao-Dong Chen
  • Publisher : Academic Press
  • Release : 31 August 2018
GET THIS BOOKA Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics

A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use


Controversies in Latin American Bioethics

Controversies in Latin American Bioethics
  • Author : Eduardo Rivera-López,Martin Hevia
  • Publisher : Springer
  • Release : 19 June 2019
GET THIS BOOKControversies in Latin American Bioethics

This book offers a first rate selection of academic articles on Latin American bioethics. It covers different issues, such as vulnerability, abortion, biomedical research with human subjects, environment, exploitation, commodification, reproductive medicine, among others. Latin American bioethics has been, to an important extent, parochial and unable to meet stringent international standards of rational philosophical discussion. The new generations of bioethicists are changing this situation, and this book demonstrates that change. All articles are written from the perspective of Latin American


Principles of Regenerative Medicine

Principles of Regenerative Medicine
  • Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
  • Publisher : Academic Press
  • Release : 16 December 2010
GET THIS BOOKPrinciples of Regenerative Medicine

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure.


Translational Regenerative Medicine

Translational Regenerative Medicine
  • Author : Anthony Atala,Julie Allickson
  • Publisher : Academic Press
  • Release : 01 December 2014
GET THIS BOOKTranslational Regenerative Medicine

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government,


The EBMT Handbook

The EBMT Handbook
  • Author : Enric Carreras,Carlo Dufour,Mohamad Mohty,Nicolaus Kröger
  • Publisher : Springer
  • Release : 12 December 2018
GET THIS BOOKThe EBMT Handbook

This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and


Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
  • Author : Lucas G. Chase,Mohan C Vemuri
  • Publisher : Springer Science & Business Media
  • Release : 12 December 2012
GET THIS BOOKMesenchymal Stem Cell Therapy

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host


Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine
  • Author : Walter C. Low,Catherine M. Verfaillie
  • Publisher : World Scientific
  • Release : 25 February 2021
GET THIS BOOKStem Cells and Regenerative Medicine

The commercialization of biotechnology has resulted in an intensive search for new biological resources for the purposes of increasing food productivity, medicinal applications, energy production, and various other applications. Although biotechnology has produced many benefits for humanity, the exploitation of the planet's natural resources has also resulted in some undesirable consequences such as diminished species biodiversity, climate change, environmental contamination, and intellectual property right and patent concerns.This book discusses the role of biological, ecological, environmental, ethical, and economic issues


Stem Cells in Clinical Practice and Tissue Engineering

Stem Cells in Clinical Practice and Tissue Engineering
  • Author : Rakesh Sharma
  • Publisher : BoD – Books on Demand
  • Release : 02 May 2018
GET THIS BOOKStem Cells in Clinical Practice and Tissue Engineering

Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters


Stem Cell Therapy for Organ Failure

Stem Cell Therapy for Organ Failure
  • Author : Indumathi Somasundaram
  • Publisher : Springer
  • Release : 02 January 2015
GET THIS BOOKStem Cell Therapy for Organ Failure

The book “STEM CELL THERAPY FOR ORGAN FAILURES” edited by Dr. S. Indumathi demonstrates the In Vitro and In vivo therapeutic strategies and applications of pre- and post-natal stem cells for treating the failures of various organ systems of our body in a wide perspective. It explores the past, present and the futuristic approach of the exciting field of stem cells and its intriguing properties involved in tissue repair and regeneration. The prime focus of this volume is to unravel


Clinical Regenerative Medicine in Urology

Clinical Regenerative Medicine in Urology
  • Author : Bup Wan Kim
  • Publisher : Springer
  • Release : 14 September 2017
GET THIS BOOKClinical Regenerative Medicine in Urology

This multidisciplinary book provides up-to-date information on clinical approaches that combine stem or progenitor cells, biomaterials and scaffolds, growth factors, and other bioactive agents in order to offer improved treatment of urologic disorders including lower urinary tract dysfunction, urinary incontinence, neurogenic bladder, and erectile dysfunction. In providing clinicians and researchers with a broad perspective on the development of regenerative medicine technologies, it will assist in the dissemination of both regenerative medicine principles and a variety of exciting therapeutic options. After



Corneal Regeneration

Corneal Regeneration
  • Author : Jorge L. Alió,Jorge L. Alió del Barrio,Francisco Arnalich-Montiel
  • Publisher : Springer
  • Release : 20 February 2019
GET THIS BOOKCorneal Regeneration

This text provides expert instruction on the varying surgical techniques currently employed for the regeneration of the ocular surface. Corneal Regeneration: Therapy and Surgery begins with a thorough discussion of current research based on data obtained in clinical human studies, and discusses the potential clinical implications for this promising new stage of eye surgery. Sections devoted to the stem cell, regenerative surgery and therapy of the ocular surface epithelium, corneal stroma, and corneal endothelium follow, each section comprehensively covering applied


Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist

Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist
  • Author : Valerie I. Brown
  • Publisher : Springer
  • Release : 22 December 2017
GET THIS BOOKHematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist

This volume provides a comprehensive and state-of-the-art review on pediatric hematopoietic stem cell transplantation (HSCT). The book covers such topics as graft versus host disease (GVHD), HSC mobilization, stem cell selection, and HSCT-relevant laboratory assays and techniques. The text is specially formatted so that the scientific basis of HSCT and ethical considerations are integrated into the relevant clinical framework. Each chapter also includes diagrams, illustrations, and tables that summarize key points and concepts that can be used as a quick


Hematopoietic Cell Transplantation for Malignant Conditions

Hematopoietic Cell Transplantation for Malignant Conditions
  • Author : Qaiser Bashir,Mehdi Hamadani
  • Publisher : Elsevier Health Sciences
  • Release : 14 February 2019
GET THIS BOOKHematopoietic Cell Transplantation for Malignant Conditions

Get a quick, expert overview of hematologic and non-hematologic malignancies for which hematopoietic cell transplantation is a treatment option. Drs. Qaiser Bashir and Mehdi Hamadani provide easy-to-find information on basic science of hematopoietic cell transplantation, pharmacology, workflows and procedures, possible complications and side effects, in addition to the role of HCT in conjunction with clinical cellular therapy. Discusses high-dose chemotherapeutic regimens and radiation therapy, patient and donor selection and workup, as well as other key aspects of hematopoietic cell transplantation.


In Situ Tissue Regeneration

In Situ Tissue Regeneration
  • Author : Sang Jin Lee,Anthony Atala,James J Yoo
  • Publisher : Academic Press
  • Release : 17 July 2016
GET THIS BOOKIn Situ Tissue Regeneration

In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body’s ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body’s own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that