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Adenosine Receptors in Neurodegenerative Diseases

Adenosine Receptors in Neurodegenerative Diseases
  • Author : David Blum
  • Publsiher : Academic Press
  • Release : 10 March 2017
  • ISBN : 0128037458
  • Pages : 280 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKAdenosine Receptors in Neurodegenerative Diseases

Summary:
Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience. Comprehensive reference that details adenosine receptors in neurodegenerative disorders, with details on brain function and possible therapeutics Gives insights on how these receptors modulate the neurodegenerative outcomes in different disorders Edited by two of the leading researchers in the field regarding adenosine role in the brain in aging and neurodegenerative conditions


Adenosine Receptors in Neurodegenerative Diseases

Adenosine Receptors in Neurodegenerative Diseases
  • Author : David Blum,Luisa V. Lopes
  • Publisher : Academic Press
  • Release : 10 March 2017
GET THIS BOOKAdenosine Receptors in Neurodegenerative Diseases

Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal


The Adenosine Receptors

The Adenosine Receptors
  • Author : Pier Andrea Borea,Katia Varani,Stefania Gessi,Stefania Merighi,Fabrizio Vincenzi
  • Publisher : Humana Press
  • Release : 28 July 2018
GET THIS BOOKThe Adenosine Receptors

This book traces the history of adenosine receptor research from molecular biology to medicinal chemistry to behavior, including their implications in disease and potential strategies as therapeutic targets. It provides the reader with a comprehensive overview of the adenosine receptors that includes information on all subtypes - A1, A2A, A2B and A3. Aspects addressed include the most up to date information on their functional distribution in the nervous and peripheral systems, behavioral roles in inflammation, cancer, pain and


Adenosine Receptors and Parkinson's Disease

Adenosine Receptors and Parkinson's Disease
  • Author : Hiroshi Kase,Peter J. Richardson,Peter Jenner
  • Publisher : Elsevier
  • Release : 27 October 1999
GET THIS BOOKAdenosine Receptors and Parkinson's Disease

This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease. Discusses the


Adenosine Receptors in Health and Disease

Adenosine Receptors in Health and Disease
  • Author : Constance N. Wilson,S. Jamal Mustafa
  • Publisher : Springer Science & Business Media
  • Release : 28 July 2009
GET THIS BOOKAdenosine Receptors in Health and Disease

Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis,


Adenosine Receptors

Adenosine Receptors
  • Author : Gyorgy Hasko,Bruce N. Cronstein,Csaba Szabo
  • Publisher : CRC Press
  • Release : 20 July 2006
GET THIS BOOKAdenosine Receptors

After a century of research, several lines of evidence now indicate that the ability of adenosine to directly control inflammatory cells has a major impact on the functions of the inflammatory and immune systems. Consequently, many promising therapeutic approaches are beginning to emerge that focus on the modulation of adenosine, including the development of compounds that interfere with the breakdown of adenosine, as well as specific agonists and antagonists of various adenosine subtypes. Some of these compounds have already entered


Adenosine

Adenosine
  • Author : Susan Masino,Detlev Boison
  • Publisher : Springer Science & Business Media
  • Release : 30 August 2012
GET THIS BOOKAdenosine

Homeostasis of key metabolites and metabolic health affects all bodily systems. Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders. Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions. Increasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve


The Adenosinergic System

The Adenosinergic System
  • Author : Micaela Morelli,Nicola Simola,Jadwiga Wardas
  • Publisher : Springer
  • Release : 01 October 2015
GET THIS BOOKThe Adenosinergic System

Adenosine A2A receptor antagonists have shown great promise in the treatment of Parkinson's Disease and alleviation of symptoms. This book addresses various aspects of this class of drugs from their chemical development to their clinical use. Among the many insightful chapters contained in this book, there are three unique reviews that have not previously been published in any format: (1) a history of istradefylline, the first A2A antagonist approved for treatment of Parkinson's Disease, (2) an overview of neuroimaging studies


Methylxanthines

Methylxanthines
  • Author : Bertil B. Fredholm
  • Publisher : Springer Science & Business Media
  • Release : 22 September 2010
GET THIS BOOKMethylxanthines

In the present volume of the Handbook of Experimental Pharmacology well known experts describe the actions of different xanthines with a focus on caffeine and theophylline. A special chapter is devoted to theobromine, an active component of chocolate, the actions of which are less well characterized. This book also presents the pharmacology of one xanthine derivative, propentofylline, as an example of a xanthine that has gone through extensive development for a novel therapeutic area.


Neuroglia in Neurodegenerative Diseases

Neuroglia in Neurodegenerative Diseases
  • Author : Alexei Verkhratsky,Margaret S. Ho,Robert Zorec,Vladimir Parpura
  • Publisher : Springer Nature
  • Release : 03 October 2019
GET THIS BOOKNeuroglia in Neurodegenerative Diseases

This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia. Accumulating evidence suggests that neuroglia participate in the neurodegenerative process, and as such are essential players in a variety of diseases, including Alzheimer’s, Parkinson’s, and Huntington’s. Intended for researchers and students, the book presents recent advances concerning the biology of


Glial Cells in Health and Disease of the CNS

Glial Cells in Health and Disease of the CNS
  • Author : Rommy von Bernhardi
  • Publisher : Springer
  • Release : 06 October 2016
GET THIS BOOKGlial Cells in Health and Disease of the CNS

A timely overview covering the three major types of glial cells in the central nervous system - astrocytes, microglia, and oligodendrocytes. New findings on glia biology are overturning a century of conventional thinking about how the brain operates and are expanding our knowledge about information processing in the brain. The book will present recent research findings on the role of glial cells in both healthy function and disease. It will comprehensively cover a broad spectrum of topics while remaining compact


Hypoxia and Human Diseases

Hypoxia and Human Diseases
  • Author : Jing Zheng,Chi Zhou
  • Publisher : BoD – Books on Demand
  • Release : 01 February 2017
GET THIS BOOKHypoxia and Human Diseases

This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners,


Parkinson's Disease and Related Disorders

Parkinson's Disease and Related Disorders
  • Author : Peter Riederer,Heinz Reichmann,Moussa B. H. Youdim,Manfred Gerlach
  • Publisher : Springer Science & Business Media
  • Release : 23 November 2006
GET THIS BOOKParkinson's Disease and Related Disorders

This book gives a comprehensive overview on current clinical and basic research issues related to Parkinson’s disease and its related disorders. The book is the result of the 16th International Congress of Parkinson’s Disease and Related disorders congress 2005. Its contents are suitable for neurologists, psychiatrists, neurosurgeons, basic researchers, geneticians and patients as well as their relatives.



Excitotoxicity in Neurological Diseases

Excitotoxicity in Neurological Diseases
  • Author : Carlo Ferrarese,M. Flint Beal
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKExcitotoxicity in Neurological Diseases

It can be reasonably anticipated that, over the next generations, the proportion of elderly people will remarkably increase and, with this, the number ofpersons suffering from acute (e.g. cerebral ischemia) or chronic neurodegenerative disorders. To date, approved drugs only alleviate the symptoms ofthese diseases (for instance, acetylcholinesterase inhibitors in Alzheimer disease and L-dopa and dopamine-agonists in Parkinson disease), while none seems to stop the progression of the degenerative processes underlying them. The development of effective preventive or protective therapies