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Mass Spectrometry Based Chemical Proteomics

Mass Spectrometry Based Chemical Proteomics
  • Author : W. Andy Tao
  • Publsiher : John Wiley & Sons
  • Release : 10 July 2019
  • ISBN : 1118970217
  • Pages : 448 pages
  • Rating : 5/5 from 1 ratings
GET THIS BOOKMass Spectrometry Based Chemical Proteomics

Summary:
PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS—EMPHASIZING MASS SPECTROMETRY THROUGHOUT Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments. The first section of Mass Spectrometry-Based Chemical Proteomics starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures. Summarizes chemical proteomics, up-to-date concepts, analysis, and target validation Covers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions Explains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics Includes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products Addresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry Mass Spectrometry-Based Chemical Proteomics is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.


Mass Spectrometry-Based Chemical Proteomics

Mass Spectrometry-Based Chemical Proteomics
  • Author : W. Andy Tao,Ying Zhang
  • Publisher : John Wiley & Sons
  • Release : 10 July 2019
GET THIS BOOKMass Spectrometry-Based Chemical Proteomics

PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS—EMPHASIZING MASS SPECTROMETRY THROUGHOUT Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and


Advances in Protein Chemistry and Structural Biology

Advances in Protein Chemistry and Structural Biology
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 16 December 2010
GET THIS BOOKAdvances in Protein Chemistry and Structural Biology

Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists


Advances in Protein Chemistry and Structural Biology

Advances in Protein Chemistry and Structural Biology
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 17 November 2015
GET THIS BOOKAdvances in Protein Chemistry and Structural Biology

The Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics. Provides cutting-edge developments in protein chemistry and structural biology Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students


Pharmacological Advances in Natural Product Drug Discovery

Pharmacological Advances in Natural Product Drug Discovery
  • Author : Guanhua Du
  • Publisher : Academic Press
  • Release : 01 March 2020
GET THIS BOOKPharmacological Advances in Natural Product Drug Discovery

Pharmacological Advances in Natural Product Drug Discovery, Volume 87 in the Advances in Pharmacology series, presents the latest pharmacological research progresses of 8 medicinal compounds from natural products, including salvianolic acid, tanshinone, paeonol, chlorogenic acid, astragaloside, icariin, ganoderan, and febrifugine. Specific chapters to this new release include Potential Role of Paeonol on Atherosclerosis Related Cells, A Review on Salvianolic Acid, Pharmacological Advances of Tanshinones, the Natural Product of Salvia Miltiorrhiza, Pharmacological Action and Potential Targets Analysis of Major Pharmacological Effects of Chlorogenic



Advances in Ion Mobility-Mass Spectrometry: Fundamentals, Instrumentation and Applications

Ion Mobility Spectrometry, Volume 83 will focuses on new trends, methods and instrumentation in the field, starting from the innovations of each technique, to the most progressive challenges of IM-MS. Chapters includes section on Recent advances in IM-MS, IM-MS Principles and Theory, IM-MS Applications and Instrumentation, and the Future of IM-MS. Presents the latest advancements in IM-MS that are essential for new applications Helps readers understand the state-of-the-art in the currently available IM-MS interfaces and their principle uses Provides information on


Advances in Potato Chemistry and Technology

Advances in Potato Chemistry and Technology
  • Author : Jaspreet Singh,Lovedeep Kaur
  • Publisher : Academic Press
  • Release : 22 July 2009
GET THIS BOOKAdvances in Potato Chemistry and Technology

Developments in potato chemistry, including identification and use of the functional components of potatoes, genetic improvements and modifications that increase their suitability for food and non-food applications, the use of starch chemistry in non-food industry and methods of sensory and objective measurement have led to new and important uses for this crop. Advances in Potato Chemistry and Technology presents the most current information available in one convenient resource.The expert coverage includes details on findings related to potato composition, new


Quantitative Proteomics

Quantitative Proteomics
  • Author : Claire E Eyers,Simon J Gaskell
  • Publisher : Royal Society of Chemistry
  • Release : 11 February 2014
GET THIS BOOKQuantitative Proteomics

As a component of post-genome science, the field of proteomics has assumed great prominence in recent years. Whereas quantitative analyses focussed initially on relative quantification, a greater emphasis is now placed on absolute quantification and consideration of proteome dynamics. Coverage of the topic of quantitative proteomics requires consideration both of the analytical fundamentals of quantitative mass spectrometry and the specific demands of the problem being addressed. Quantitative Proteomics aims to outline the state of the art in mass spectrometry-based quantitative


Plant Proteomics

Plant Proteomics
  • Author : Ganesh K. Agrawal,Randeep Rakwal
  • Publisher : John Wiley & Sons
  • Release : 03 October 2008
GET THIS BOOKPlant Proteomics

Confidently face the challenges of proteomics research specific to plant science with the information in Plant Proteomics, which will introduce you to the techniques and methodologies required for the study of representative plant species. Read about proteomics studies in Arabidopsis, rice, and legumes and find information about common technologies like mass spectrometry and gel electrophoresis. Discover expression proteomics, functional proteomics, structural proteomics, bioinformatics, and systems biology, understand how to conduct proteomics studies in developing countries and underfunded laboratories, and gain


Chemical Proteomics

Chemical Proteomics
  • Author : Gerard Drewes,Marcus Bantscheff
  • Publisher : Humana Press
  • Release : 17 November 2011
GET THIS BOOKChemical Proteomics

The multidisciplinary science of chemical proteomics studies how small molecules of synthetic or natural origin bind to proteins and modulate their function. In Chemical Proteomics: Methods and Protocols, expert researchers in the field provide key techniques to investigate chemical proteomics focusing on analytical strategies, how probes are generated, techniques for the discovery of small molecule targets and the probing of target function, and small molecule ligand and drug discovery. Written in the highly successful Methods in Molecular BiologyTM series format,



Advances in Clinical Chemistry

Advances in Clinical Chemistry
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 24 June 2005
GET THIS BOOKAdvances in Clinical Chemistry

Volume thirty-nine in the internationally acclaimed Advances in Clinical Chemistry, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting edge microarray technology. In keeping with the tradition of the series, this volume emphasizes novel laboratory advances with application not only to both clinical laboratory diagnostics, but as well as practical basic science studies. This volume of Advances in


Recent Advances in Proteomics Research

Recent Advances in Proteomics Research
  • Author : Ming D. Li
  • Publisher : Nova Science Pub Incorporated
  • Release : 01 January 2013
GET THIS BOOKRecent Advances in Proteomics Research

The primary objective of this book is to provide updated knowledge of recent advances in proteomics research in various fields. The topics covered include, but are not limited to, proteomic analysis for microbiomes, specific cell types from heterogeneous tissues, body fluids, mitochondria, and environmental toxicology. Almost all proteomics techniques currently used in research have been reviewed in at least one chapter, including traditional one- or two-dimensional gel-based, gel-free shotgun, label-based or label-free quantitative, and array-based methods. In addition, although they


Advances in Clinical Chemistry

Advances in Clinical Chemistry
  • Author : Gregory Makowski
  • Publisher : Academic Press
  • Release : 01 July 2007
GET THIS BOOKAdvances in Clinical Chemistry

Volume forty-four of the Advances in Clinical Chemistry series contains review articles of wide interest to clinical laboratory scientists and diagnostic adventurers. Articles in this volume cover such topics as Caspases in Myocardial Infarction; Deamidated Gliadin Peptides as Targets for Celiac Disease Specific Antibodies; Urokinase Receptor Variants in Tissue and Body Fluids; Proteomics in Cancer; Paraneoplastic Neurological Syndromes and Oncnerual Antibodies: Clinical and Immunological Aspects; Pathophysiologic Mechanisms of Angiogenesis; Bikunin (Urinary Trypsin Inhibitor): Structure, Biological Relevance and Measurement; and Gene


Nucleoproteins—Advances in Research and Application: 2013 Edition

Nucleoproteins—Advances in Research and Application: 2013 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release : 21 June 2013
GET THIS BOOKNucleoproteins—Advances in Research and Application: 2013 Edition

Nucleoproteins—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Histones. The editors have built Nucleoproteins—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Histones in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nucleoproteins—Advances in Research and Application: 2013 Edition has been produced