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Annotating New Genes

Annotating New Genes
  • Author : Shizuka Uchida
  • Publsiher : Elsevier
  • Release : 06 August 2012
  • ISBN : 1908818123
  • Pages : 196 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKAnnotating New Genes

Summary:
In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases and software available, before moving on to cover programming guidelines, including a specific case study on the use of C-It for in silico screening. The second half of the book offers a step-by-step guide to experimental validation concepts and procedures, as well as an overview of additional potential applications of this approach in the field of stem cells and tissue regeneration, before a concluding chapter summarises the concepts and theories presented. Focuses not only on screening but also on biological validations Provides details of databases and software (web interface) products for biologists with minimal computation skills Offers a step-by-step outline of the procedure involved


Annotating New Genes

Annotating New Genes
  • Author : Shizuka Uchida
  • Publisher : Elsevier
  • Release : 06 August 2012
GET THIS BOOKAnnotating New Genes

In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases

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Bioinformatics and Functional Genomics

Bioinformatics and Functional Genomics
  • Author : Jonathan Pevsner
  • Publisher : John Wiley & Sons
  • Release : 04 March 2005
GET THIS BOOKBioinformatics and Functional Genomics

Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key

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Development of New Tools and Pipelines for Plant Bioinformatics Applications

Development of New Tools and Pipelines for Plant Bioinformatics Applications
  • Author : Omar M. Darwish
  • Publisher : Anonim
  • Release : 25 September 2021
GET THIS BOOKDevelopment of New Tools and Pipelines for Plant Bioinformatics Applications

Blueberry is an economically and nutritionally important small fruit crop, native to North America. As with many crops, extreme low temperature can affect blueberry crop yield negatively and cause major losses to growers. For this reason, blueberry breeding programs have focused on developing improved cultivars with broader climatic adaptation. To help achieve this goal, the blueberry genomic database (BBGD454) was developed to provide the research community with valuable resources to identify genes that play an important role in flower bud

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Gene Prediction

Gene Prediction
  • Author : Martin Kollmar
  • Publisher : Humana Press
  • Release : 19 May 2019
GET THIS BOOKGene Prediction

This volume introduces software used for gene prediction with focus on eukaryotic genomes. The chapters in this book describe software and web server usage as applied in common use-cases, and explain ways to simplify re-annotation of long available genome assemblies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary computational requirements, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough,

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Sequence — Evolution — Function

Sequence — Evolution — Function
  • Author : Eugene V. Koonin,Michael Galperin
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOKSequence — Evolution — Function

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the

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The Tomato Genome

The Tomato Genome
  • Author : Mathilde Causse,Jim Giovannoni,Mondher Bouzayen,Mohamed Zouine
  • Publisher : Springer
  • Release : 21 November 2016
GET THIS BOOKThe Tomato Genome

This book describes the strategy used for sequencing, assembling and annotating the tomato genome and presents the main characteristics of this sequence with a special focus on repeated sequences and the ancestral polyploidy events. It also includes the chloroplast and mitochondrial genomes. Tomato (Solanum lycopersicum) is a major crop plant as well as a model for fruit development, and the availability of the genome sequence has completely changed the paradigm of the species’ genetics and genomics. The book describes the

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The Carrot Genome

The Carrot Genome
  • Author : Philipp Simon,Massimo Iorizzo,Dariusz Grzebelus,Rafal Baranski
  • Publisher : Springer
  • Release : 08 May 2019
GET THIS BOOKThe Carrot Genome

This book provides an up-to-date review and analysis of the carrot’s nuclear and organellar genome structure and evolution. In addition, it highlights applications of carrot genomic information to elucidate the carrot’s natural and agricultural history, reproductive biology, and the genetic basis of traits important in agriculture and human health. The carrot genome was sequenced in 2016, and its relatively small diploid genome, combined with the fact that it is the most complete root crop genome released to date and

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An Integrated Approach to Enhancing Functional Annotation of Sequences for Data Analysis of a Transcriptome

An Integrated Approach to Enhancing Functional Annotation of Sequences for Data Analysis of a Transcriptome
  • Author : Matthew Morritt Hindle
  • Publisher : Anonim
  • Release : 25 September 2021
GET THIS BOOKAn Integrated Approach to Enhancing Functional Annotation of Sequences for Data Analysis of a Transcriptome

Given the ever increasing quantity of sequence data, functional annotation of new gene sequences persists as being a significant challenge for bioinformatics. This is a particular problem for transcriptomics studies in crop plants where large genomes and evolutionarily distant model organisms, means that identifying the function of a given gene used on a microarray, is often a non-trivial task. Information pertinent to gene annotations is spread across technically and semantically heterogeneous biological databases. Combining and exploiting these data in a

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The Gene Ontology Handbook

The Gene Ontology Handbook
  • Author : Christophe Dessimoz,Nives Skunca
  • Publisher : Anonim
  • Release : 08 October 2020
GET THIS BOOKThe Gene Ontology Handbook

This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing

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Genomics, Proteomics, and Metabolomics

Genomics, Proteomics, and Metabolomics
  • Author : Babak Arjmand
  • Publisher : Springer Nature
  • Release : 14 November 2019
GET THIS BOOKGenomics, Proteomics, and Metabolomics

This book provides thorough coverage of high-throughput OMICs technologies for the monitoring of stem cells and regenerative medicine. Specific topics covered include the genomics, proteomics, and metabolomics aspects of regenerative medicine, metabolic profiling of mesenchymal stem cells, genome profiling of mesenchymal stem cells, OMICs monitoring of stem cell-derived exosomes, stem cell proteomics, lipidomics, OMICs profiling of cancer (stem) cells, and finally ethical considerations of OMICs-based investigations. Chapters are authored by world-renowned scientists who have valuable expertise in the field of

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The Potato Genome

The Potato Genome
  • Author : Swarup Kumar Chakrabarti,Conghua Xie,Jagesh Kumar Tiwari
  • Publisher : Springer
  • Release : 26 December 2017
GET THIS BOOKThe Potato Genome

This book describes the historical importance of potato (Solanum tuberosum L.),potato genetic resources and stocks (including S. tuberosum group Phureja DM1-3 516 R44, a unique doubled monoploid homozygous line) used for potato genome sequencing. It also discusses strategies and tools for high-throughput sequencing, sequence assembly, annotation, analysis, repetitive sequences and genotyping-by-sequencing approaches. Potato (Solanum tuberosum L.; 2n = 4x = 48) is the fourth most important food crop of the world after rice, wheat and maize and holds great potential to ensure

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The Sports Gene

The Sports Gene
  • Author : David Epstein
  • Publisher : Penguin
  • Release : 01 August 2013
GET THIS BOOKThe Sports Gene

The New York Times bestseller – with a new afterword about early specialization in youth sports – by the author of Range: Why Generalists Triumph in a Specialized World. The debate is as old as physical competition. Are stars like Usain Bolt, Michael Phelps, and Serena Williams genetic freaks put on Earth to dominate their respective sports? Or are they simply normal people who overcame their biological limits through sheer force of will and obsessive training? In this controversial and engaging exploration

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Plant Genomes

Plant Genomes
  • Author : Jean-Nicolas Volff
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 01 January 2008
GET THIS BOOKPlant Genomes

Recent major advances in the field of comparative genomics and cytogenomics of plants, particularly associated with the completion of ambitious genome projects, have uncovered astonishing facets of the architecture and evolutionary history of plant genomes. The aim of this book was to review these recent developments as well as their implications in our understanding of the mechanisms which drive plant diversity. New insights into the evolution of gene functions, gene families and genome size are presented, with particular emphasis on

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IMG ER

IMG ER
  • Author : Anonim
  • Publisher : Anonim
  • Release : 25 September 2021
GET THIS BOOKIMG ER

A rapidly increasing number of microbial genomes are sequenced by organizations worldwide and are eventually included into various public genome data resources. The quality of the annotations depends largely on the original dataset providers, with erroneous or incomplete annotations often carried over into the public resources and difficult to correct. We have developed an Expert Review (ER) version of the Integrated Microbial Genomes (IMG) system, with the goal of supporting systematic and efficient revision of microbial genome annotations. IMG ER

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