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Antimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial Peptides in Gastrointestinal Diseases
  • Author : Chi Hin Cho
  • Publsiher : Academic Press
  • Release : 06 June 2018
  • ISBN : 0128143207
  • Pages : 186 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKAntimicrobial Peptides in Gastrointestinal Diseases

Summary:
Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs. AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa. More importantly, AMPs possess diversified anti-microbial actions against various infectious diseases in the GI tract. With these physiological functions and pharmacological actions, AMPs have significant potential as therapeutic agents for the treatment of inflammation, cancer and further infection in the GI tract. Provides an overview of AMPs, particularly cathelicidin and defensin, in different diseases Covers inflammation and ulcer repair in the stomach and colon and carcinogenesis in the GI tract Presents AMP information and knowledge in a concise manner Gives useful information on all aspects of AMPs Promotes research on AMPs and their development as drugs, from bench, to clinical application


Antimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial Peptides in Gastrointestinal Diseases
  • Author : Chi Hin Cho
  • Publisher : Academic Press
  • Release : 06 June 2018
GET THIS BOOKAntimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only


Antimicrobial Peptides

Antimicrobial Peptides
  • Author : Jürgen Harder,Jens-M. Schröder
  • Publisher : Springer
  • Release : 24 December 2015
GET THIS BOOKAntimicrobial Peptides

This book focuses on the importance of human antimicrobial peptides (AMP) in keeping the host healthy and preventing infectious diseases. The first chapters deal with several examples of the role of AMP in different epithelial organs (skin and wound healing, eye, lung, genito-urinary tract, gut), which are exposed to different kinds of infectious microorganisms and as a result produce different patterns of AMP. Examples of the dysregulation of AMP expression and function promoting infections are discussed. The capacity of AMP


Crohn's Disease and Ulcerative Colitis

Crohn's Disease and Ulcerative Colitis
  • Author : Daniel C. Baumgart
  • Publisher : Springer
  • Release : 01 March 2017
GET THIS BOOKCrohn's Disease and Ulcerative Colitis

This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex


Nutraceutical Proteins and Peptides in Health and Disease

Nutraceutical Proteins and Peptides in Health and Disease
  • Author : Yoshinori Mine,Fereidoon Shahidi
  • Publisher : CRC Press
  • Release : 29 September 2005
GET THIS BOOKNutraceutical Proteins and Peptides in Health and Disease

Reports of the beneficial health effects of some peptides have begun to make their way into the scientific literature. Peptides can act as immunomodulators, and have been shown to have a positive influence on calcium absorption, and on regulation of serum cholesterol. A number of peptides may also possess antimicrobial properties that enhance the body's defense mechanisms, and others may produce inhibitory effects for angiotensin-I-converting enzyme (ACE), leading to novel treatments for blood pressure conditions, heart failure, and diabetes. Modern


Milk Proteins

Milk Proteins
  • Author : Isabel Gigli
  • Publisher : BoD – Books on Demand
  • Release : 07 September 2016
GET THIS BOOKMilk Proteins

Milk proteins have nutritional value and extraordinary biological properties. Research over the last decades has provided new insight into the structure and the function of milk bioactive peptides. Some of these peptides are delivered directly into milk, and some are encrypted in major proteins such as caseins and lactoglobulins. These peptides have antimicrobial functions modulating the gut microflora. Even when milk is undisputedly the first food for mammals, milk proteins sometimes can be a health threat, either because of allergic


Peptide Drug Discovery and Development

Peptide Drug Discovery and Development
  • Author : Miguel Castanho,Nuno Santos
  • Publisher : John Wiley & Sons
  • Release : 24 October 2011
GET THIS BOOKPeptide Drug Discovery and Development

Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the "bench to bedside" translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug development in the preclinical as well as clinical stages. The first part provides a general background and focuses on the characteristic strengths and weaknesses of peptide drugs. The second section contains five cases studies of peptides from


Handbook of Biologically Active Peptides

Handbook of Biologically Active Peptides
  • Author : Abba Kastin
  • Publisher : Academic Press
  • Release : 26 January 2013
GET THIS BOOKHandbook of Biologically Active Peptides

Handbook of Biologically Active Peptides, Second Edition, is the definitive, indispensable reference for peptide researchers, biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and endocrinologists. Its chapters are designed to be a source for workers in the field and enable researchers working in a specific area to examine related areas outside their expertise. Peptides play a crucial role in many physiological processes, including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology,


New Weapons to Control Bacterial Growth

New Weapons to Control Bacterial Growth
  • Author : Tomas G. Villa,Miguel Vinas
  • Publisher : Springer
  • Release : 24 March 2016
GET THIS BOOKNew Weapons to Control Bacterial Growth

Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages



Prokaryotic Antimicrobial Peptides

Prokaryotic Antimicrobial Peptides
  • Author : Djamel Drider,Sylvie Rebuffat
  • Publisher : Springer Science & Business Media
  • Release : 08 March 2011
GET THIS BOOKProkaryotic Antimicrobial Peptides

The book will provide an overview of the advancement of fundamental knowledge and applications of antimicrobial peptides in biomedical, agricultural, veterinary, food, and cosmetic products. Antimicrobial peptides stand as potentially great alternatives to current antibiotics, and most research in this newly-created area has been published in journals and other periodicals. It is the editors’ opinion that it is timely to sum up the most important achievements in the field and provide the scientific community in a reference book. The goals


Intestinal Immune System

Intestinal Immune System
  • Author : Soichiro Miura,Ryota Hokari
  • Publisher : Biota Publishing
  • Release : 01 August 2011
GET THIS BOOKIntestinal Immune System

In the intestine, a unique immunological system that is different from the systemic immune system exists to provide adaptive immunity in response to luminal bacteria and dietary antigens. There are many lymphoid cell aggregates called gut-associated lymphoid tissue (GALT) including Peyer’s patches (PPs), which function as important induction sites for the mucosal immune response. M-cells are present in the epithelium of PPs, having a specialized structure for uptake of macromolecules such as bacteria. In addition to GALT, there are


Pathogenesis of Periodontal Diseases

Pathogenesis of Periodontal Diseases
  • Author : Nagihan Bostanci,Georgios N. Belibasakis
  • Publisher : Springer
  • Release : 25 September 2017
GET THIS BOOKPathogenesis of Periodontal Diseases

This book aims to provide clinicians with a refined understanding of the biology that underlies periodontal diseases, thereby offering a sound basis for improved clinical decision making with regard to prevention strategies, diagnosis, and therapy. All significant aspects of periodontal pathogenesis are covered, including the roles played by the oral microbiome and biofilms, bacterial virulence factors, cells of the immune system, matrix metalloproteinases, proinflammatory and osteolytic cytokines, genetic factors, and antimicrobial peptides. Periodontal diseases are among the most common infectious


Antimicrobial Peptides

Antimicrobial Peptides
  • Author : David A. Phoenix,Sarah R. Dennison,Frederick Harris
  • Publisher : John Wiley & Sons
  • Release : 27 December 2012
GET THIS BOOKAntimicrobial Peptides

In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design


Probiotics

Probiotics
  • Author : Shymaa Enany
  • Publisher : BoD – Books on Demand
  • Release : 04 July 2018
GET THIS BOOKProbiotics

Probiotic has been used for centuries especially in fermented dairy products since Metchnikoff associated the intake of fermented milk with prolonged life. Probiotics confer many health benefits to humans, animals, and plants when administered in proper amounts. These benefits include the prevention of gastrointestinal infections and antibiotic-associated diarrhea, the reduction of serum cholesterol and allergenic and atopic complaints, and the protection of the immune system. Furthermore, the proper usage of probiotics could suppress Helicobacter pylori infection and Crohn's disease, improve


Trends in Regulatory Peptides

Trends in Regulatory Peptides
  • Author : Hubert Vaudry,Marie-Christine Tonon,David Vaudry
  • Publisher : Frontiers Media SA
  • Release : 24 July 2018
GET THIS BOOKTrends in Regulatory Peptides

Regulatory peptides represent the most diverse and versatile family of messenger molecules. They are produced by all living organisms from bacteria to mammals. They are involved in a wide variety of biological functions. Biologically active peptides and their receptors thus constitute an unlimited source of inspiration for the development of innovative drugs and cosmetics. The present eBook is a unique collection of research articles and reviews that provide a representative examplification of the latest progress in regulatory peptide research.