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Artemisinin Based and Other Antimalarials

Artemisinin Based and Other Antimalarials
  • Author : Guoqiao Li
  • Publsiher : Academic Press
  • Release : 28 November 2017
  • ISBN : 0128132116
  • Pages : 736 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKArtemisinin Based and Other Antimalarials

Summary:
Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery


Artemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials
  • Author : Guoqiao Li,Ying Li,Zelin Li,Meiyi Zeng
  • Publisher : Academic Press
  • Release : 28 November 2017
GET THIS BOOKArtemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable


Saving Lives, Buying Time

Saving Lives, Buying Time
  • Author : Institute of Medicine,Board on Global Health,Committee on the Economics of Antimalarial Drugs
  • Publisher : National Academies Press
  • Release : 09 October 2004
GET THIS BOOKSaving Lives, Buying Time

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called “artemisinins†are available, they are unaffordable for the majority of the affected population, even at a


Artemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials
  • Author : Guoqiao Li,Ying Li,Zelin Li,Meiyi Zeng
  • Publisher : Academic Press
  • Release : 28 November 2017
GET THIS BOOKArtemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable


Antimalarial Chemotherapy

Antimalarial Chemotherapy
  • Author : Philip J. Rosenthal
  • Publisher : Springer Science & Business Media
  • Release : 01 April 2001
GET THIS BOOKAntimalarial Chemotherapy

Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy:


Treatment and Prevention of Malaria

Treatment and Prevention of Malaria
  • Author : Henry M. Staines,Sanjeev Krishna
  • Publisher : Springer Science & Business Media
  • Release : 06 January 2012
GET THIS BOOKTreatment and Prevention of Malaria

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the


Towards Malaria Elimination

Towards Malaria Elimination
  • Author : Sylvie Manguin,Vas Dev
  • Publisher : BoD – Books on Demand
  • Release : 18 July 2018
GET THIS BOOKTowards Malaria Elimination

Towards Malaria Elimination - A Leap Forward was started to mark the occasion for renewed commitment to end malaria transmission for good (the WHO's call for "Malaria Free World" by 2030). This book is dedicated for the benefit of researchers, scientists, program and policy managers, students and anyone interested in malaria and other mosquito-borne diseases with the goal of sharing recent information on success stories, innovative control approaches and challenges in different regions of the world. Some main issues that emerged



Guidelines for the Treatment of Malaria

Guidelines for the Treatment of Malaria
  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release : 03 March 2021
GET THIS BOOKGuidelines for the Treatment of Malaria

"The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV positive, travellers from non-malaria endemic regions) and in complex emergency situations and severe malaria."--Publisher's description.


Guidelines for the Treatment of Malaria. Third Edition

Guidelines for the Treatment of Malaria. Third Edition
  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release : 13 August 2015
GET THIS BOOKGuidelines for the Treatment of Malaria. Third Edition

Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all


Antimalarial Agents

Antimalarial Agents
  • Author : Graham L. Patrick
  • Publisher : Elsevier
  • Release : 30 May 2020
GET THIS BOOKAntimalarial Agents

Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work towards antimalarial solution, providing practical guidance on current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world’s population. Advances over the last decade have seen vast improvements in the effectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs


An Overview of Tropical Diseases

An Overview of Tropical Diseases
  • Author : Amidou Samie
  • Publisher : BoD – Books on Demand
  • Release : 02 December 2015
GET THIS BOOKAn Overview of Tropical Diseases

Tropical diseases affect millions of people throughout the world and particularly in the developing countries. The millennium development goals had specifically targeted HIV/AIDS and Malaria for substantial reduction as well as Tuberculosis while many other tropical diseases have been neglected. The new sustainable development goals have not made such distinction and have targeted all diseases for elimination for the improvement of the quality of life of human beings on earth. The present book was developed to provide an update



Traditional Medicinal Plants and Malaria

Traditional Medicinal Plants and Malaria
  • Author : Merlin Willcox,Gerard Bodeker,Philippe Rasoanaivo,Jonathan Addae-Kyereme
  • Publisher : CRC Press
  • Release : 28 June 2004
GET THIS BOOKTraditional Medicinal Plants and Malaria

Malaria is an increasing worldwide threat, with more than three hundred million infections and one million deaths every year. The worlds poorest are the worst affected, and many treat themselves with traditional herbal medicines. These are often more available and affordable, and sometimes are perceived as more effective than conventional antimala


Pharmacokinetics and Pharmacodynamics of Antimalarial Drugs Used in Combination Therapy

Pharmacokinetics and Pharmacodynamics of Antimalarial Drugs Used in Combination Therapy
  • Author : Qigui Li,Mark R. Hickman
  • Publisher : Bentham Science Publishers
  • Release : 04 June 2015
GET THIS BOOKPharmacokinetics and Pharmacodynamics of Antimalarial Drugs Used in Combination Therapy

Malaria takes a great toll on human health and well-being, particularly in tropical regions including Sub-Saharan Africa, Southeast Asia, Oceania and parts of the Americas. In recent years, some Plasmodium strains have become increasingly resistant to all classes of conventional antimalarial drugs currently in use. Researchers have, therefore, stepped up efforts to revise atimalarial drug policies, develop new drugs, and implement new strategies to combat this disease. In order to prevent widespread resistance, antimalarial combination therapies (ACTs) have been deployed


Artemisia annua - Pharmacology and Biotechnology

Artemisia annua - Pharmacology and Biotechnology
  • Author : Tariq Aftab,Jorge F.S. Ferreira,M. Masroor A. Khan,M. Naeem
  • Publisher : Springer Science & Business Media
  • Release : 26 November 2013
GET THIS BOOKArtemisia annua - Pharmacology and Biotechnology

Artemisinin, a sesquiterpene lactone originally extracted from the medicinal plant Artemisia annua L., is an effective antimalarial agent, particularly for multi-drug resistant and cerebral malaria. However, the concentration of artemisinin in the plant is very low. Because the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source of artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A.