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Bioconjugate Techniques

Bioconjugate Techniques
  • Author : Greg T. Hermanson
  • Publsiher : Academic Press
  • Release : 25 July 2013
  • ISBN : 0123822408
  • Pages : 1200 pages
  • Rating : 5/5 from 1 ratings
GET THIS BOOKBioconjugate Techniques

Summary:
Bioconjugate Techniques, 3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates Features full color illustrations Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented


Bioconjugate Techniques

Bioconjugate Techniques
  • Author : Greg T. Hermanson
  • Publisher : Academic Press
  • Release : 25 July 2013
GET THIS BOOKBioconjugate Techniques

Bioconjugate Techniques, 3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers.

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Bioconjugate Techniques

Bioconjugate Techniques
  • Author : Greg T. Hermanson
  • Publisher : Academic Press
  • Release : 26 July 2010
GET THIS BOOKBioconjugate Techniques

Bioconjugate Techniques, 2nd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or cross linking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic

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Bioconjugate Techniques

Bioconjugate Techniques
  • Author : Greg T. Hermanson
  • Publisher : Academic Press
  • Release : 15 January 1996
GET THIS BOOKBioconjugate Techniques

Bioconjugate Techniques is the essential guide to the modification and crosslinking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. Armed with this

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Chemistry of Bioconjugates

Chemistry of Bioconjugates
  • Author : Ravin Narain
  • Publisher : John Wiley & Sons
  • Release : 02 December 2013
GET THIS BOOKChemistry of Bioconjugates

Explores bioconjugate properties and applications ofpolymers, dendrimers, lipids, nanoparticles, and nanotubes Bioconjugation has enabled breakthroughs across many areas ofindustry and biomedicine. With its emphasis on synthesis,properties and applications, this book enables readers tounderstand the connection between chemistry and the biologicalapplication of bioconjugated materials. Its detailed descriptionsof methods make it possible for researchers to fabricate and takefull advantage of bioconjugates for a broad range of applications.Moreover, the book sets the foundation for the development of newapplications, including assays, imaging,

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Chemical Linkers in Antibody-Drug Conjugates (ADCs)

Chemical Linkers in Antibody-Drug Conjugates (ADCs)
  • Author : Floris van Delft,John M. Lambert
  • Publisher : Royal Society of Chemistry
  • Release : 22 December 2021
GET THIS BOOKChemical Linkers in Antibody-Drug Conjugates (ADCs)

Chemical Linkers in Antibody-Drug Conjugates aims to shine a detailed light on the various key attributes of chemical linkers in ADCs, for drug-to-antibody ratio, for stability, for release mechanism of payload, for pharmacokinetics, for stability determination, and for efficacy and safety.

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Immobilized Affinity Ligand Techniques

Immobilized Affinity Ligand Techniques
  • Author : Greg T. Hermanson,A. Krishna Mallia,Paul K. Smith
  • Publisher : Academic Press
  • Release : 10 September 1992
GET THIS BOOKImmobilized Affinity Ligand Techniques

This book is a practical guide to the preparation and use of immobilized affinity ligands for purification, catalysis, and analysis. Special emphasis is given to immunochemical techniques including antibody isolation, preparation of antibody fragments using immobilized enzymes, and immunoaffinity chromatography. The book provides easy-to-follow, well-tested protocols to allow the uninitiated to use these techniques to the maximum advantage with minimum hassle. In addition, it shows researchers how to save money by making their own optimized affinity supports. Matrix activation: Ligand

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Antibody-Drug Conjugates

Antibody-Drug Conjugates
  • Author : L. Nathan Tumey
  • Publisher : Anonim
  • Release : 20 August 2022
GET THIS BOOKAntibody-Drug Conjugates

This volume looks at key methodologies that are commonly used across antibody drug conjugates (ADCs) programs. The chapters in this book cover topics such as conjugations to endogenous cysteine residues; click chemistry conjugations; antibody conjugations via glycosyl remodeling; analysis of ADCs by native mass spectrometry; characterization of ADCs by capillary electrophoresis; LC/MS methods for studying lysosomal ADC catabolism; and determination of ADC concentration by ligand-binding assays. Written in the highly successful Methods in Molecular Biology series format, chapters include

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Enzyme Immunoassays

Enzyme Immunoassays
  • Author : S.S. Deshpande
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKEnzyme Immunoassays

This unique reference provides a pragmatic approach to the development of successful commercial immunodiagnostic products based on enzyme immunoessay technology. Presenting both the basic and applied principles, Enzyme Immunoassays gathers information on all aspects of this process, from the initial conceptualization to the introduction of the product to the market.

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Antibody-Drug Conjugates

Antibody-Drug Conjugates
  • Author : Kenneth J. Olivier, Jr.,Sara A. Hurvitz
  • Publisher : John Wiley & Sons
  • Release : 14 November 2016
GET THIS BOOKAntibody-Drug Conjugates

Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. • Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies • Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging • Includes case studies of ADCs in oncology drug development • Features contributions from highly-regarded experts on the frontlines of

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Bioconjugation

Bioconjugation
  • Author : Sam Massa,Nick Devoogdt
  • Publisher : Anonim
  • Release : 20 August 2022
GET THIS BOOKBioconjugation

This book explores well-established and emerging conjugation strategies that are relevant for proteins used in the field of precision medicine, focusing on techniques that are suitable for antibodies, antibody-fragments such as Fabs, scFvs, or nanobodies, scaffold proteins such as FN3 or DARPin, peptides, or model proteins. Although centered on the development of bioconjugates rather than their application, most protocols also show the conjugation of the targeting vehicle to a diagnostic or therapeutic entity, with the end-product most often being an

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Characterization of Pharmaceutical Nano- and Microsystems

Characterization of Pharmaceutical Nano- and Microsystems
  • Author : Leena Peltonen
  • Publisher : John Wiley & Sons
  • Release : 16 October 2020
GET THIS BOOKCharacterization of Pharmaceutical Nano- and Microsystems

Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement

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Click Triazoles

Click Triazoles
  • Author : Janez Košmrlj
  • Publisher : Springer
  • Release : 30 May 2012
GET THIS BOOKClick Triazoles

B. R. Buckley and H. Heaney: Mechanistic Investigations of Copper(I)- Catalyzed Alkyne–Azide Cycloaddition Reactions.- J. D. Crowley and D. A. McMorran: “Click-Triazole” Coordination Chemistry: Exploiting 1,4-Disubstituted-1,2,3-Triazoles as Ligands.- S. Lee and A. H. Flood: Binding Anions in Rigid and Reconfigurable Triazole Receptors.- M. Watkinson: Click Triazoles as Chemosensors.- H.-F. Chow, C.-M. Lo and Y. Chen: Triazole-Based Polymer Gels.- T. Zheng, S. H. Rouhanifard, A. S. Jalloh, P. Wu: Click

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Carbohydrate Chemistry

Carbohydrate Chemistry
  • Author : Amelia Pilar Rauter,Thisbe K. Lindhorst,Yves Queneau
  • Publisher : Royal Society of Chemistry
  • Release : 31 October 2016
GET THIS BOOKCarbohydrate Chemistry

With the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in their field. This invaluable volume contains analysed, evaluated and distilled information on the latest in carbohydrate research. The discovery and synthesis of novel carbohydrates and mimetics with diverse applications continues to be a major challenge for carbohydrate chemists. The understanding of the structure and function of carbohydrates and glycoconjugates remains vital in medicine and molecular biology.

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Functional Hydrogels in Drug Delivery

Functional Hydrogels in Drug Delivery
  • Author : Umile Gianfranco Spizzirri,Giuseppe Cirillo
  • Publisher : CRC Press
  • Release : 10 August 2017
GET THIS BOOKFunctional Hydrogels in Drug Delivery

The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high performing carriers for specific uses.

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