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Immunomodulatory Biomaterials

Immunomodulatory Biomaterials
  • Author : Stephen F. Badylak
  • Publsiher : Woodhead Publishing
  • Release : 30 July 2021
  • ISBN : 0128214562
  • Pages : 294 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKImmunomodulatory Biomaterials

Summary:
Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an “inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response Provides a single reference for understanding and utilizing the host response in biomaterials design An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area


Immunomodulatory Biomaterials

Immunomodulatory Biomaterials
  • Author : Stephen F. Badylak,Jennifer Elisseeff
  • Publisher : Woodhead Publishing
  • Release : 30 July 2021
GET THIS BOOKImmunomodulatory Biomaterials

Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an “inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative

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Biomaterials and Immune Response

Biomaterials and Immune Response
  • Author : Nihal Engin Vrana
  • Publisher : CRC Press
  • Release : 20 July 2018
GET THIS BOOKBiomaterials and Immune Response

The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted

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Host Response to Biomaterials

Host Response to Biomaterials
  • Author : Stephen F Badylak
  • Publisher : Academic Press
  • Release : 08 May 2015
GET THIS BOOKHost Response to Biomaterials

Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the

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Biomaterials and Tissue Engineering

Biomaterials and Tissue Engineering
  • Author : Donglu Shi
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOKBiomaterials and Tissue Engineering

The current interest in developing novel materials has motivated an increasing need for biological and medical studies in a variety of dinical applications. Indeed, it is dear that to achieve the requisite mechanical, chemical and biomedical properties, especially for new bioactive materials, it is necessary to develop novel synthesis routes. The tremendous success of materials science in developing new biomaterials and fostering technological innovation arises from its focus on interdisciplinary research and collaboration between materials and medical sciences. Materials scientists

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The Immune Response to Implanted Materials and Devices

The Immune Response to Implanted Materials and Devices
  • Author : Bruna Corradetti
  • Publisher : Springer
  • Release : 30 November 2016
GET THIS BOOKThe Immune Response to Implanted Materials and Devices

This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development

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Adverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing

Adverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing
  • Author : Nihal Engin Vrana,Amir M. Ghaemmaghami,Pinar Zorlutuna
  • Publisher : Frontiers Media SA
  • Release : 15 May 2019
GET THIS BOOKAdverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing

Adverse immune reactions to biomaterials are important bottlenecks for translation of novel biomaterials for clinical use. Moreover, recent advances in highthrough-put biomaterial discovery and synthetic biology, while providing exciting new veues, also significantly increases potential risks related to the in vivo reactions to these new materials. For example, the novel materials might have unintended biological activities due to their natural building blocks. In this perspective, biomaterial field needs i) better understanding of cell/biomaterial interactions at systems level; ii) development

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Biomaterials in Regenerative Medicine and the Immune System

Biomaterials in Regenerative Medicine and the Immune System
  • Author : Laura Santambrogio
  • Publisher : Springer
  • Release : 04 September 2015
GET THIS BOOKBiomaterials in Regenerative Medicine and the Immune System

The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as

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Biomaterials in Tissue Engineering and Regenerative Medicine

Biomaterials in Tissue Engineering and Regenerative Medicine
  • Author : Birru Bhaskar,Parcha Sreenivasa Rao,Naresh Kasoju,Vasagiri Nagarjuna,Rama Raju Baadhe
  • Publisher : Springer Nature
  • Release : 29 April 2021
GET THIS BOOKBiomaterials in Tissue Engineering and Regenerative Medicine

This book comprehensively explores the basic concepts and applications of biomaterials in tissue engineering and regenerative medicine. The book is divided into four sections; the first section deals with the basic concepts and different types of biomaterials used in tissue engineering. The second section discusses the functional requirements and types of materials that are used in developing state-of-the-art of scaffolds for tissue engineering applications. The third section presents the applications of biomaterials for hard and soft tissue engineering, as well

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Biomaterials in Translational Medicine

Biomaterials in Translational Medicine
  • Author : Lei Yang,Sarit Bhaduri,Thomas J. Webster
  • Publisher : Academic Press
  • Release : 30 November 2018
GET THIS BOOKBiomaterials in Translational Medicine

Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in

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Cellular Response to Biomaterials

Cellular Response to Biomaterials
  • Author : Lucy Di Silvio
  • Publisher : Elsevier
  • Release : 22 December 2008
GET THIS BOOKCellular Response to Biomaterials

The response of cells to biomaterials is critical in medical devices. Traditionally inert biomaterials were used to minimise the reaction in cells in contact with the material. However, it has been realised that specific cell responses may be beneficial in such areas as encouraging adhesion, healing or cell multiplication. Cellular response to biomaterials discusses the response of cells to a wide range of biomaterials targeted at specific medical applications. Part one discusses cell responses to a variety of polymers and

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Cellulose Chemistry and Properties: Fibers, Nanocelluloses and Advanced Materials

Cellulose Chemistry and Properties: Fibers, Nanocelluloses and Advanced Materials
  • Author : Orlando J. Rojas
  • Publisher : Springer
  • Release : 25 February 2016
GET THIS BOOKCellulose Chemistry and Properties: Fibers, Nanocelluloses and Advanced Materials

Vincent Bulone et al.: Cellulose sources and new understanding of synthesis in plants Thomas Heinze et al.:Cellulose structure and properties Thomas Rosenau, Antje Potthast, Ute Henniges et al.: Recent developments in cellulose aging (degradation / yellowing / chromophore formation) Sunkyu Park et al.:Cellulose crystallinity Lina Zhang et al.:Gelation and dissolution behavior of cellulose Yoshiyuki Nishio et al.:Cellulose and derivatives in liquid crystals Alessandro Gandini, Naceur Belgacem et al.:The surface and in-depth modification of cellulose fibers Emily D.

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Regenerative Medicine Applications in Organ Transplantation

Regenerative Medicine Applications in Organ Transplantation
  • Author : Giuseppe Orlando
  • Publisher : Academic Press
  • Release : 11 October 2013
GET THIS BOOKRegenerative Medicine Applications in Organ Transplantation

Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation

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Biomaterials in Regenerative Medicine

Biomaterials in Regenerative Medicine
  • Author : Leszek A. Dobrzański
  • Publisher : BoD – Books on Demand
  • Release : 14 February 2018
GET THIS BOOKBiomaterials in Regenerative Medicine

The book Biomaterials in Regenerative Medicine is addressed to the engineers and mainly medical practitioners as well as scientists and PhD degree students. The book indicates the progress in research and in the implementation of the ever-new biomaterials for the application of the advanced types of prosthesis, implants, scaffolds and implant-scaffolds including personalised ones. The book presents a theoretical approach to the synergy of technical, biological and medical sciences concerning materials and technologies used for medical and dental implantable devices

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Mechanism of Biomaterial Adjuvant Effect

Mechanism of Biomaterial Adjuvant Effect
  • Author : Mutsumi Yoshida
  • Publisher : Anonim
  • Release : 25 June 2022
GET THIS BOOKMechanism of Biomaterial Adjuvant Effect

Development of combination products such as tissue engineered constructs which combine biomaterials with biologics has prompted the need to clarify the role of biomaterial in potentiating the immune response towards the biological component due to adjuvant effect. In tissue engineering applications, immune responses are to be minimized while vaccine strategies seek to enhance the protective immune response. Thesis project presented herein showed that adjuvant effect of poly(lactic-co-glycolic acid) (PLGA) is mediated in part by maturation of dendritic cells (DCs),

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Biomaterials for Oral and Dental Tissue Engineering

Biomaterials for Oral and Dental Tissue Engineering
  • Author : Lobat Tayebi,Keyvan Moharamzadeh
  • Publisher : Woodhead Publishing
  • Release : 28 July 2017
GET THIS BOOKBiomaterials for Oral and Dental Tissue Engineering

Biomaterials for Oral and Dental Tissue Engineering examines the combined impact of materials, advanced techniques and applications of engineered oral tissues. With a strong focus on hard and soft intraoral tissues, the book looks at how biomaterials can be manipulated and engineered to create functional oral tissue for use in restorative dentistry, periodontics, endodontics and prosthodontics. Covering the current knowledge of material production, evaluation, challenges, applications and future trends, this book is a valuable resource for materials scientists and researchers

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