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Biometals in Neurodegenerative Diseases

Biometals in Neurodegenerative Diseases
  • Author : Anthony R. White
  • Publsiher : Academic Press
  • Release : 28 April 2017
  • ISBN : 0128045639
  • Pages : 462 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKBiometals in Neurodegenerative Diseases

Summary:
Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases. Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics. Authoritative and timely resource bringing together the major findings in the field for those with an interest in metals and their role in the brain function, disease, and as therapeutic targets Written for academic researchers, clinicians and advanced graduate students studying, or treating, patients in neurodegeneration, neurochemistry, neurology and neurotoxicology Edited by international leaders in the field who have contributed greatly to the study of metals in neurodegenerative diseases


Biometals in Neurodegenerative Diseases

Biometals in Neurodegenerative Diseases
  • Author : Anthony R. White,Michael Aschner,Lucio G. Costa,Ashley I. Bush
  • Publisher : Academic Press
  • Release : 28 April 2017
GET THIS BOOKBiometals in Neurodegenerative Diseases

Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or

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Metals and Neurodegeneration: Restoring the Balance

Metals and Neurodegeneration: Restoring the Balance
  • Author : Anthony R. White,Katja M. Kanninen,Peter J. Crouch
  • Publisher : Frontiers Media SA
  • Release : 02 February 2016
GET THIS BOOKMetals and Neurodegeneration: Restoring the Balance

Biometals such as copper, zinc and iron have key biological functions, however, aberrant metabolism can lead to detrimental effects on cell function and survival. These biometals have important roles in the brain, driving cellular respiration, antioxidant activity, intracellular signaling and many additional structural and enzymatic functions. There is now considerable evidence that abnormal biometal homeostasis is a key feature of many neurodegenerative diseases and may have an important role in the onset and progression of disorders such as Alzheimer’s,

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Metal Related Neurodegenerative Disease

Metal Related Neurodegenerative Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 07 November 2013
GET THIS BOOKMetal Related Neurodegenerative Disease

This issue reviews the role of metals in neurodegenerative diseases; including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented. This volume of International Review of Neurobiology brings together cutting-edge research on metal related neurodegenerative disease It reviews the role of metals in neurodegenerative diseases, including Parkinson’s and Huntington’s disease;

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Nervous System Diseases—Advances in Research and Treatment: 2013 Edition

Nervous System Diseases—Advances in Research and Treatment: 2013 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release : 21 June 2013
GET THIS BOOKNervous System Diseases—Advances in Research and Treatment: 2013 Edition

Nervous System Diseases—Advances in Research and Treatment: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Neuromuscular Diseases. The editors have built Nervous System Diseases—Advances in Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neuromuscular Diseases in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nervous System Diseases—Advances

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Frontiers in Clinical Drug Research - Dementia: Volume 1

Frontiers in Clinical Drug Research - Dementia: Volume 1
  • Author : Atta-ur-Rahman
  • Publisher : Bentham Science Publishers
  • Release : 02 June 2020
GET THIS BOOKFrontiers in Clinical Drug Research - Dementia: Volume 1

Frontiers in Clinical Drug Research - Dementia is a book series which presents comprehensive reviews about research on Dementia, - the loss of brain function associated with Alzheimer’s disease and other related medical conditions. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for dementia and related disorders. This

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Combustion Emissions

Combustion Emissions
  • Author : Keith Schofield
  • Publisher : Academic Press
  • Release : 10 January 2020
GET THIS BOOKCombustion Emissions

Combustion Emissions: Formation, Reaction, and Removal of Trace Metals in Combustion Products presents the latest scientific knowledge on combustion, with a particular focus on the behavior of elements in this high temperature method of energy generation. The book describes methods of control and establishes a solid base of understanding for future research. Encyclopedic in style and consistent in format, each chapter systematically presents a complete analysis of the combustion behavior of each element and guides the reader in resolving specific

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Research Anthology on Diagnosing and Treating Neurocognitive Disorders

Research Anthology on Diagnosing and Treating Neurocognitive Disorders
  • Author : Management Association, Information Resources
  • Publisher : IGI Global
  • Release : 30 August 2020
GET THIS BOOKResearch Anthology on Diagnosing and Treating Neurocognitive Disorders

Cognitive impairment, through Alzheimer’s disease or other related forms of dementia, is a serious concern for afflicted individuals and their caregivers. Understanding patients’ mental states and combatting social stigmas are important considerations in caring for cognitively impaired individuals. Technology is playing an increasing role in the lives of the elderly. One of the most prevalent developments for the aging population is the use of technological innovations for intervention and treatment of individuals with mental impairments. Research Anthology on Diagnosing

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Metal-Based Neurodegeneration

Metal-Based Neurodegeneration
  • Author : Robert Crichton,Roberta Ward
  • Publisher : John Wiley & Sons
  • Release : 04 September 2013
GET THIS BOOKMetal-Based Neurodegeneration

Neurodegenerative diseases of the human brain appear in variousforms, resulting in disorders of movement and coordination,cognitive deterioration and psychiatric disturbances. Many of thekey factors leading to neurodegenerative diseases are similar,including the dysfunction of metal ion homeostasis, redox-activemetal ions generating oxidative stress, and intracellular inclusionbodies. Metal-based Neurodegeneration presents a detailed surveyof the molecular origins of neurodegenerative diseases. Eachchapter is dedicated to a specific disease, presenting the latestscientific findings, including details of their biochemicalactors (proteins or peptides), their normal and

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Manganese in Health and Disease

Manganese in Health and Disease
  • Author : Lucio G Costa,Michael Aschner
  • Publisher : Royal Society of Chemistry
  • Release : 27 November 2014
GET THIS BOOKManganese in Health and Disease

Manganese in the diet is nutritionally essential for normal physiologic functioning. However, excessive exposure to manganese has been associated with developmental, neurodegenerative and other disorders. The book comprehensively covers the toxicology of manganese. Leading investigators provide perspectives from toxicology, neuroscience, nutrition, molecular biology and risk assessment disciplines and chapters cover the toxicokinetics, toxicodynamic interactions and health effects of manganese, as well as its potential role in neurodegenerative diseases. A large section devoted to health effects presents the latest research that

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Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America

Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America
  • Author : Agustín Ibáñez,Lucas Sedeño,Adolfo M. García,Robert M.J. Deacon,Patricia Cogram
  • Publisher : Frontiers Media SA
  • Release : 21 June 2018
GET THIS BOOKHuman and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America

Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and

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Iron as Therapeutic Targets in Human Diseases

Iron as Therapeutic Targets in Human Diseases
  • Author : Paolo Arosio,Maura Poli,Raffaella Gozzelino
  • Publisher : MDPI
  • Release : 11 February 2020
GET THIS BOOKIron as Therapeutic Targets in Human Diseases

Iron is an essential element for almost all organisms, a cofactor playing a crucial role in a number of vital functions, including oxygen transport, DNA synthesis, and respiration. However, its ability to exchange electrons renders excess iron potentially toxic, since it is capable of catalyzing the formation of highly poisonous free radicals. As a consequence, iron homeostasis is tightly controlled by sophisticated mechanisms that have been partially elucidated. Because of its biological importance, numerous disorders have been recently linked to

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Magnesium in the Central Nervous System

Magnesium in the Central Nervous System
  • Author : Robert Vink,Mihai Nechifor
  • Publisher : University of Adelaide Press
  • Release : 26 June 2022
GET THIS BOOKMagnesium in the Central Nervous System

The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the

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Iron Metabolism

Iron Metabolism
  • Author : Robert Crichton
  • Publisher : John Wiley & Sons
  • Release : 31 May 2016
GET THIS BOOKIron Metabolism

Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a

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