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Biotextiles as Medical Implants

Biotextiles as Medical Implants
  • Author : M W King
  • Publsiher : Elsevier
  • Release : 31 October 2013
  • ISBN : 0857095609
  • Pages : 704 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKBiotextiles as Medical Implants

Summary:
Textiles play a vital role in the manufacture of various medical devices, including the replacement of diseased, injured or non-functioning organs within the body. Biotextiles as medical implants provides an invaluable single source of information on the main types of textile materials and products used for medical implants. The first part of the book focuses on polymers, fibers and textile technologies, and these chapters discuss the manufacture, sterilization, properties and types of biotextiles used for medical applications, including nanofibers, resorbable polymers and shaped biotextiles. The chapters in part two provide a comprehensive discussion of a range of different clinical applications of biotextiles, including surgical sutures, arterial prostheses, stent grafts, percutaneous heart valves and drug delivery systems. This book provides a concise review of the technologies, properties and types of biotextiles used as medical devices. In addition, it addresses the biological dimension of how to design devices for different clinical applications, providing an invaluable reference for biomedical engineers of medical textiles, quality control and risk assessment specialists, as well as managers of regulatory affairs. The subject matter will also be of interest to professionals within the healthcare system including surgeons, nurses, therapists, sourcing and purchasing agents, researchers and students in different disciplines. Provides an invaluable single source of information on the main types of textile materials and products used for medical implants Addresses the technologies used and discusses the manufacture, properties and types of biotextiles Examines applications of biotextiles as medical implants, including drug delivery systems and stent grafts and percutaneous heart valves


Biotextiles as Medical Implants

Biotextiles as Medical Implants
  • Author : M W King,B S Gupta,R Guidoin
  • Publisher : Elsevier
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as Medical Implants

Textiles play a vital role in the manufacture of various medical devices, including the replacement of diseased, injured or non-functioning organs within the body. Biotextiles as medical implants provides an invaluable single source of information on the main types of textile materials and products used for medical implants. The first part of the book focuses on polymers, fibers and textile technologies, and these chapters discuss the manufacture, sterilization, properties and types of biotextiles used for medical applications, including nanofibers, resorbable

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : C.C. Chu
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

Catgut and collagen are the two most well-known natural materials for absorbable sutures; however collagen-based absorbable sutures have largely been replaced by synthetic materials made from one of five basic building blocks. The chemical structures of a variety of commercial absorbable sutures are reviewed. The characteristics, chemistry and manufacture of some nonabsorbable equivalents are also considered. A number of newly available materials, in particular the group of amino-acid based biodegradable poly(ester amide) fibers, are considered, together with the results

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : E. Duncan
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

The chapter describes the regulatory framework applicable to medical devices, and specifically to biotextiles, principally in the United States, but also in the European Union. With the emergence of new technologies and materials, new forms of regulation have become necessary, and some of the traditional classifications no longer match present-day applications. Problems encountered by manufacturers with regard to premarket approval clearance and material supply quality standards assurance are discussed, as well as issues increasingly arising when one biotextile-based medical device

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : B.S. Gupta
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

Textiles are known to have unique properties that lend themselves to use in many different types of technical products, among which perhaps the best known are medical materials. Presented in this chapter are aspects of polymer, fiber and textile science that should serve as useful background knowledge of the materials used in constructing products and whose in vitro and in vivo physical and mechanical performances are discussed in this book.

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : B.S. Gupta
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

The available implants can be classified as either the one- dimensional, two-dimensional or three-dimensional structures. Among these, the most researched is the arterial prosthesis, which involves a novel process and many steps to make. All aspects of the manufacture and finishing of different types of vascular grafts (straight, tapered, multilimbed) are discussed: construction of the basic tube, setting and annealing of the tube in corrugated and resilient circular configurations, and the designs to resist fraying, improve flow and enhance healing.

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : S.W. Shalaby,S.D. Nagatomi,E.F. Powell
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

Biotextile sterilization presents unique challenges. The chapter describes the principles of sterilization and the way in which sterility assurance levels are defined and demonstrated. Traditional thermal, chemical and radiation sterilization methods are described, as well as newer methods such as plasma and microwave sterilization, and applications for which each is suitable. The advantages of the emerging technology of radiochemical sterilization are described, together with some of its successful applications, such as surgical sutures and tissue adhesive and the results of

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : C.R. Gajjar,M.W. King,R. Guidoin
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

The biocompatibility, biofunctionality and biostability of a prosthesis, its degradation and the host response are determined through an implant retrieval study. This chapter focuses on various aspects of analyzing retrieved biotextile implants. Sample preparation techniques, analytical test methods and different test standards are reviewed. Some precautions and the limitations of implant retrieval studies are also discussed.

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : S.H. Kim,Y. Jung
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

The chapter discusses the characteristics of resorbable polymers used for medical applications, in particular in cardiovascular systems, in terms of their biocompatibility, resorbability, mechanical and degradation properties, manufacturing feasibility, sterilizability and shelf life. Polymers currently in use for biotextile applications are surveyed, together with recent advances in mechano-active engineering of tissues, especially for blood vessel regeneration, using fibrous elastic degradable polymer scaffolds.

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : R. Guidoin,M.W. King,L. Wang,Z. Zhang,R. Guzman,G. Marinov,Y. Douville
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

The chapter discusses the advantages and limitations of arterial prostheses (or vascular grafts) in terms of their biocompatibility, biofunctionality and biostability. Criteria for biomaterials selection and prosthesis design that have enabled patients to recover more rapidly without any device-related complications are reviewed, and developments are considered that may lead to future improvements in healing and clinical outcomes for the next generation of vascular prostheses.

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : B.S. Gupta,A.K. Moghe
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

Three-dimensional nanofiber structures are desirable as scaffolds for tissue development since they mimic the natural environment of the cells. Various techniques have evolved to fabricate such structures using desired materials. Among these, electrospinning provides an advantage due to the ease of use and better control of the resulting structure. A detailed account of the factors influencing the process is presented along with the current status of the technology to produce novel structures at nano level. Case studies are also included

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : G. Marinov,R. Guidoin,L.W. Tse,A.A. Ruthrauff,T. Yao,M.W. King
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

The chapter describes the pathology of aneurysms and explains the technique of endovascular aortic repair. The development of stent grafts is reviewed and a number of different types are described and evaluated. The use of branched stent grafts and in situ fenestration techniques for patients with more challenging anatomies is discussed.

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : C.C. Chu
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

The chapter describes properties of materials used for sutures that may be: absorbable or nonabsorbable; of varying size; made from monofilament, multifilament, twisted or braided threads. The characteristics of a large number of synthetic suture materials are described, together with essential suture properties such as tensile strength, knot strength, elasticity, tissue reaction and biodegradability. The interrelated nature of the essential physical and mechanical, handling, biological and biodegradation properties is emphasized. The use of dyes and coatings to improve suture identification

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Biotextiles as medical implants

Biotextiles as medical implants
  • Author : B.S. Gupta
  • Publisher : Elsevier Inc. Chapters
  • Release : 31 October 2013
GET THIS BOOKBiotextiles as medical implants

Arterial grafts first appeared in the early 1950s, since when they have attracted much attention and undergone significant changes in structure and treatment. Arterial prostheses are now routinely used to correct arterial flow disorders. The success of large-diameter synthetic arteries has not been experienced in with small-caliber vessels. A major reason is the lack of transverse compliance, leading to mismatch in elastic stretch at the anastomoses and to failure. The chapter discusses the factors affecting compliance and methods of measuring

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