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Cell Polarity in Development and Disease

Cell Polarity in Development and Disease
  • Author : Douglas W Houston
  • Publsiher : Academic Press
  • Release : 14 November 2017
  • ISBN : 0128125918
  • Pages : 236 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKCell Polarity in Development and Disease

Summary:
Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research. Provides basic science understanding of cell polarity disease and development Covers diseases affecting polarized epithelial tissues in the lung and kidney, also covering the progression of cancer Includes historical context of cell polarity research for potential future breakthroughs


Cell Polarity in Development and Disease

Cell Polarity in Development and Disease
  • Author : Douglas W Houston
  • Publisher : Academic Press
  • Release : 14 November 2017
GET THIS BOOKCell Polarity in Development and Disease

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting

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Cell Polarity 2

Cell Polarity 2
  • Author : Klaus Ebnet
  • Publisher : Springer
  • Release : 24 February 2015
GET THIS BOOKCell Polarity 2

This work provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 2 discusses the physiological and pathophysiological relevance of cell polarity. It especially focuses on pathophysiological conditions in which one or several aspects of cell polarity are impaired, and in which a loss of cell polarity possibly contributes to disease (e.g. epithelial-to-mesenchymal transition in cancer, role of polarity proteins in cancer). Both volumes are intended for professors, group leaders and researchers in cell biology as

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Amphibian Models of Development and Disease

Amphibian Models of Development and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 30 May 2021
GET THIS BOOKAmphibian Models of Development and Disease

Amphibian Models of Development and Disease, Volume 145 in the Current Topics in Developmental Biology series, highlights new advances in the field written by an international board of experts. New chapters in this release include Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons from the analysis

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Cellular Networks in Development

Cellular Networks in Development
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 02 April 2021
GET THIS BOOKCellular Networks in Development

Current Topics in Developmental Biology, Volume 143, the latest release in this acclaimed series, highlights new advances in the field, with this new volume presenting new sections on Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Left-right asymmetry research in Xenopus: Questions solved and new frontiers, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons

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Cystogenesis

Cystogenesis
  • Author : Jong Hoon Park,Curie Ahn
  • Publisher : Springer
  • Release : 12 October 2016
GET THIS BOOKCystogenesis

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted

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GTPases Regulating Membrane Dynamics

GTPases Regulating Membrane Dynamics
  • Author : W. E. Balch,Channing J. Der,Alan Hall
  • Publisher : Gulf Professional Publishing
  • Release : 27 December 2005
GET THIS BOOKGTPases Regulating Membrane Dynamics

GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations to understand membrane architecture of eukaryotic cells. This volume of MIE provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their rapidly expanding list of regulators and

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Developmental and Stem Cell Biology in Health and Disease

Developmental and Stem Cell Biology in Health and Disease
  • Author : Ahmed El-Hashash
  • Publisher : Bentham Science Publishers
  • Release : 14 July 2016
GET THIS BOOKDevelopmental and Stem Cell Biology in Health and Disease

Research into stem cells started in the 1960s with experiments on spleen cultures. Evans and Kaufman made a breakthrough in mouse embryo culturing and embryonic stem cell extraction in 1981, followed by the work of Thomson in 1998 on the technique for extracting human embryonic stem cells. Since then, stem cell research has rapidly expanded as a therapeutic avenue for different diseases in humans. This book explains the basic developmental biology of stem cells including the development of stem cells during the

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Extracellular Matrix Degradation

Extracellular Matrix Degradation
  • Author : William C. Parks,Robert Mecham
  • Publisher : Springer Science & Business Media
  • Release : 07 April 2011
GET THIS BOOKExtracellular Matrix Degradation

Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases,

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Tissue Remodeling and Epithelial Morphogenesis

Tissue Remodeling and Epithelial Morphogenesis
  • Author : Thomas Lecuit
  • Publisher : Academic Press
  • Release : 09 October 2009
GET THIS BOOKTissue Remodeling and Epithelial Morphogenesis

For more than 30 years, Current Topics in Developmental Biology has provided a forum for dissemination and discussion of new ideas and thought in developmental biology. Bringing together a series of articles on the structural, functional, and developmental characteristics of epithelials, this thematic volume represents a timely and valuable contribution to an exciting and multidisciplinary field of study. Because defects in epithelial function and growth control play a major role in human disease-cancerous tumors, spina bifida, cardiac malformations, for example-this volume

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