• Home
  • Cell Surface GRP78 a New Paradigm in Signal Transduction Biology

Cell Surface GRP78 a New Paradigm in Signal Transduction Biology

Cell Surface GRP78  a New Paradigm in Signal Transduction Biology
  • Author : Salvatore V. Pizzo
  • Publsiher : Academic Press
  • Release : 20 March 2018
  • ISBN : 0128123524
  • Pages : 144 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKCell Surface GRP78 a New Paradigm in Signal Transduction Biology

Summary:
Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease Provides four-color illustrations that facilitate the narrative


Cell Surface GRP78, a New Paradigm in Signal Transduction Biology

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology
  • Author : Salvatore V. Pizzo
  • Publisher : Academic Press
  • Release : 20 March 2018
GET THIS BOOKCell Surface GRP78, a New Paradigm in Signal Transduction Biology

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. Edited by the researcher who identified cell surface expression

Book Cell Surface GRP78, a New Paradigm in Signal Transduction Biology PDF Download/ Read Online


Extracellular Matrix Biomineralization of Dental Tissue Structures

Extracellular Matrix Biomineralization of Dental Tissue Structures
  • Author : Michel Goldberg,Pamela Den Besten
  • Publisher : Springer Nature
  • Release : 30 September 2021
GET THIS BOOKExtracellular Matrix Biomineralization of Dental Tissue Structures

This book addresses the structural and biological properties of dental and peridental tissue structures and covers their mineralization process. The book contains a description of dentines, cementum, enamel and bone, including collagens, as well as non-collagenous proteins (SIBLINGs, SLRPs, GAGs, PGs, lipids, and MMPs). The mechanisms of mineralization are described in detail and the book is focused on matrix vesicles, collagen mineralization and the role of non-collagenous extracellular matrix components either as promoters or inhibitors of mineralization. In addition, the

Book Extracellular Matrix Biomineralization of Dental Tissue Structures PDF Download/ Read Online


Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies
  • Author : Ramasamy Paulmurugan,Tarik F. Massoud
  • Publisher : Academic Press
  • Release : 25 June 2021
GET THIS BOOKGlioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists,

Book Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies PDF Download/ Read Online


Mechanisms of Insulin Action

Mechanisms of Insulin Action
  • Author : Alan R. Saltiel,Jeffrey E. Pessin
  • Publisher : Springer Science & Business Media
  • Release : 05 October 2007
GET THIS BOOKMechanisms of Insulin Action

More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.

Book Mechanisms of Insulin Action PDF Download/ Read Online


Current Research Topics in Plant Virology

Current Research Topics in Plant Virology
  • Author : Aiming Wang,Xueping Zhou
  • Publisher : Springer
  • Release : 07 July 2016
GET THIS BOOKCurrent Research Topics in Plant Virology

Topics covered in this book include RNA silencing and its suppression in plant virus infection, virus replication mechanisms, the association of cellular membranes with virus replication and movement, plant genetic resistance to viruses, viral cell-to-cell spread, long distance movement in plants, virus induced ER stress, virus diversity and evolution, virus-vector interactions, cross protection, geminiviruses, negative strand RNA viruses, viroids, and the diagnosis of plant viral diseases using next generation sequencing. This book was anticipated to help plant pathologists, scholars, professors,

Book Current Research Topics in Plant Virology PDF Download/ Read Online


Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease

Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease
  • Author : Deric L. Wheeler,Yosef Yarden
  • Publisher : Springer
  • Release : 26 November 2014
GET THIS BOOKReceptor Tyrosine Kinases: Structure, Functions and Role in Human Disease

Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease, for the first time, systematically covers the shared structural and functional features of the RTK family. Receptor Tyrosine Kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases. And over the last decade they have become the Number 1 targets of cancer drugs. To be able to conduct fundamental research or to attempt to develop pharmacological agents able to enhance or intercept them, it is essential first to understand

Book Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease PDF Download/ Read Online


HSF1 and Molecular Chaperones in Biology and Cancer

HSF1 and Molecular Chaperones in Biology and Cancer
  • Author : Marc Laurence Mendillo,David Pincus,Ruth Scherz-Shouval
  • Publisher : Springer Nature
  • Release : 15 April 2020
GET THIS BOOKHSF1 and Molecular Chaperones in Biology and Cancer

Protein homeostasis, or “Proteostasis”, lies at the heart of human health and disease. From the folding of single polypeptide chains into functional proteins, to the regulation of intracellular signaling pathways, to the secreted signals that coordinate cells in tissues and throughout the body, the proteostasis network operates to support cell health and physiological fitness. However, cancer cells also hijack the proteostasis network and many of these same processes to sustain the growth and spread of tumors. The chapters in this

Book HSF1 and Molecular Chaperones in Biology and Cancer PDF Download/ Read Online


Systems Biology of Tumor Dormancy

Systems Biology of Tumor Dormancy
  • Author : Heiko Enderling,Nava Almog,Lynn Hlatky
  • Publisher : Springer Science & Business Media
  • Release : 09 November 2012
GET THIS BOOKSystems Biology of Tumor Dormancy

This volume is based on the Workshop on Systems Biology of Tumor Dormancy meeting, held July 25th to July 28th, 2011. The first annual CCSB workshop brought together biologists, clinicians, mathematicians, and computer scientists to discuss various aspects of tumor dormancy and develop novel mathematical/computational models with the keynote speakers. Specific topics included the angiogenic switch, immune system interactions, cancer stem cells and signaling.

Book Systems Biology of Tumor Dormancy PDF Download/ Read Online


Protein Degradation

Protein Degradation
  • Author : R. John Mayer,Aaron J. Ciechanover,Martin Rechsteiner
  • Publisher : Wiley-VCH
  • Release : 15 April 2005
GET THIS BOOKProtein Degradation

The first volume in a new series dedicated to protein degradation, this book lays the foundations of targeted protein breakdown via the ubiquitin pathway. The outstanding importance of the ubiquitin pathway has been recognized with the 2004 Nobel Prize in Chemistry for Aaaron Chiechanover, Avram Hershko, and Irwin Rose. Aaron Ciechanover is one of the editors of this series, and Avram Hershko has contributed to the opening chapter of the present volume. Drawing on the the expertise of two Nobel prize

Book Protein Degradation PDF Download/ Read Online



Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions

Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions
  • Author : Seyed Ehtesham Hasnain,Nasreen Z. Ehtesham,Sonam Grover
  • Publisher : Springer Nature
  • Release : 30 November 2019
GET THIS BOOKMycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions

This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease. Despite being completely curable, tuberculosis is still one of the leading global causes of death. M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. Presenting a wealth of information on the molecular infection

Book Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions PDF Download/ Read Online


Taurine 10

Taurine 10
  • Author : Dong-Hee Lee,Stephen W. Schaffer,Eunkyue Park,Ha Won Kim
  • Publisher : Springer
  • Release : 28 August 2017
GET THIS BOOKTaurine 10

Taurine 10 contains original articles and critical reviews based on the oral and poster presentations of XX International Taurine Meeting held in Seoul, Korea in May 2016. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition.

Book Taurine 10 PDF Download/ Read Online


Cell Reprogramming for Immunotherapy

Cell Reprogramming for Immunotherapy
  • Author : Samuel G. Katz,Peter M. Rabinovich
  • Publisher : Humana
  • Release : 28 November 2019
GET THIS BOOKCell Reprogramming for Immunotherapy

This volume details key protocols for developing strategies in immunotherapy. Chapters guide the readers through protocols related to various DNA, RNA and protein methods to reprogram the immune system, immune cells, analyzing the effect of the reprogrammed cells, and key methods to consider and analyze patients enrolled in clinical trials with novel immunotherapy regimens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step,

Book Cell Reprogramming for Immunotherapy PDF Download/ Read Online


The Unfolded Protein Response and Cellular Stress

The Unfolded Protein Response and Cellular Stress
  • Author : P. Michael Conn
  • Publisher : Academic Press
  • Release : 20 August 2022
GET THIS BOOKThe Unfolded Protein Response and Cellular Stress

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation The authors explain how these methods are able to provide important

Book The Unfolded Protein Response and Cellular Stress PDF Download/ Read Online


Calcium Signaling

Calcium Signaling
  • Author : Md. Shahidul Islam
  • Publisher : Springer Nature
  • Release : 23 October 2019
GET THIS BOOKCalcium Signaling

This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future

Book Calcium Signaling PDF Download/ Read Online