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Drug Repurposing in Cancer Therapy

Drug Repurposing in Cancer Therapy
  • Author : Kenneth K.W. To
  • Publsiher : Academic Press
  • Release : 29 July 2020
  • ISBN : 0128199032
  • Pages : 458 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKDrug Repurposing in Cancer Therapy

Summary:
Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource. Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types


Drug Repurposing in Cancer Therapy

Drug Repurposing in Cancer Therapy
  • Author : Kenneth K.W. To,William C.S. Cho
  • Publisher : Academic Press
  • Release : 29 July 2020
GET THIS BOOKDrug Repurposing in Cancer Therapy

Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and


Drug Repurposing in Cancer Therapy

Drug Repurposing in Cancer Therapy
  • Author : Kenneth K.W. To,William C.S. Cho
  • Publisher : Academic Press
  • Release : 17 August 2020
GET THIS BOOKDrug Repurposing in Cancer Therapy

Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and


Natural Products and Cancer Drug Discovery

Natural Products and Cancer Drug Discovery
  • Author : Farid A. Badria
  • Publisher : BoD – Books on Demand
  • Release : 05 July 2017
GET THIS BOOKNatural Products and Cancer Drug Discovery

This book, Natural Products and Cancer Drug Discovery, is written by leading experts in natural products in cancer therapy. The first two sections describe new applications of common herbs and foods for treatment of cancer. Section 3 deals with the development of new chemotherapeutics from Cannabis and endophytic fungi. Section 4 presented formulations of natural products for treatment of malignant melanoma. Made-to-order anticancer therapy from natural products using computational and tissue engineering approaches is addressed in the fifth section. It is our


In Silico Drug Design

In Silico Drug Design
  • Author : Kunal Roy
  • Publisher : Academic Press
  • Release : 12 February 2019
GET THIS BOOKIn Silico Drug Design

In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. Other topics include in silico drug design methods, computational workflows for drug repurposing, and network-based in silico screening for drug efficacy. With contributions from experts in the field and the


pH-Interfering Agents as Chemosensitizers in Cancer Therapy

pH-Interfering Agents as Chemosensitizers in Cancer Therapy
  • Author : Claudiu Supuran,Simone Carradori
  • Publisher : Academic Press
  • Release : 15 September 2020
GET THIS BOOKpH-Interfering Agents as Chemosensitizers in Cancer Therapy

pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological applications. The book is structured with innovative outlines and a distinction between experimental and clinical results. The continuous discovery and assessment of the role played by old/new synthetic drugs, natural compounds and technological applications has led to the urgent need of classification in terms of


Metallo-Drugs: Development and Action of Anticancer Agents

Metallo-Drugs: Development and Action of Anticancer Agents
  • Author : Astrid Sigel,Helmut Sigel,Eva Freisinger,Roland K.O. Sigel
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release : 05 February 2018
GET THIS BOOKMetallo-Drugs: Development and Action of Anticancer Agents

Volume 18, entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV)


Drug Repositioning: Current Advances and Future Perspectives

Drug Repositioning: Current Advances and Future Perspectives
  • Author : Yuhei Nishimura,Hideaki Hara
  • Publisher : Frontiers Media SA
  • Release : 11 January 2019
GET THIS BOOKDrug Repositioning: Current Advances and Future Perspectives

Drug repositioning is the process of identifying new indications for existing drugs. At present, the conventional de novo drug discovery process requires an average of about 14 years and US$2.5 billion to approve and launch a drug. Drug repositioning can reduce the time and cost of this process because it takes advantage of drugs already in clinical use for other indications or drugs that have cleared phase I safety trials but have failed to show efficacy in the intended diseases. Historically,


Resistance to Targeted Therapies Against Adult Brain Cancers

Resistance to Targeted Therapies Against Adult Brain Cancers
  • Author : Amanda Tivnan
  • Publisher : Springer
  • Release : 26 November 2016
GET THIS BOOKResistance to Targeted Therapies Against Adult Brain Cancers

This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for


Drug Repositioning

Drug Repositioning
  • Author : Michael J. Barratt,Donald E. Frail
  • Publisher : John Wiley & Sons
  • Release : 29 May 2012
GET THIS BOOKDrug Repositioning

With Viagra the most famous example, drug repositioning has been growing in importance for pharmaceutical companies seeking to reinvigorate development pipelines. This book provides a broad overview of drug repositioning including the business reasons and unique opportunities and challenges. Its coverage also presents a number of current and emerging technologies that are being applied, along with relevant case studies, as well as neglected diseases to consider. Pharmaceutical researchers will learn how to use drug repositioning techniques to increase the lifespan



Colorectal Cancer

Colorectal Cancer
  • Author : Jindong Chen
  • Publisher : BoD – Books on Demand
  • Release : 16 May 2018
GET THIS BOOKColorectal Cancer

With international experts sharing their experience and knowledge on these different aspects in the management of colorectal cancer, this book has this opportunity to offer all physicians treating colorectal cancer, as well as researchers, updated information concerning the biology, diagnosis, screening, and treatment of colorectal carcinoma. This book provides a detailed evaluation of diagnostic modalities, in-depth analysis of screening for colorectal cancer, recent advances in treatment, and principles and trends in the management of colorectal cancer. This updated knowledge will



Immunotherapy in Translational Cancer Research

Immunotherapy in Translational Cancer Research
  • Author : Laurence J. N. Cooper,Elizabeth A. Mittendorf,Judy Moyes,Sabitha Prabhakaran
  • Publisher : John Wiley & Sons
  • Release : 01 May 2018
GET THIS BOOKImmunotherapy in Translational Cancer Research

A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies.


A Global Scientific VisionPrevention, Diagnosis, and Treatment of Lung Cancer

A Global Scientific VisionPrevention, Diagnosis, and Treatment of Lung Cancer
  • Author : Marta Adonis
  • Publisher : BoD – Books on Demand
  • Release : 01 March 2017
GET THIS BOOKA Global Scientific VisionPrevention, Diagnosis, and Treatment of Lung Cancer

Lung cancer is the number one cause of cancer deaths around the world. This devastating disease takes strength not only in people who smoke but also in poor people that eat polluted food and use heating sources, and in those exposed naturally to toxic compounds present in indoor and outdoor environments. Lung cancer patients and their families wait actions from the science that give not only answer to their demands but also a light of hope at the moment of


How to Starve Cancer

How to Starve Cancer
  • Author : Jane McLelland
  • Publisher : Agenor Publishing
  • Release : 13 October 2020
GET THIS BOOKHow to Starve Cancer

After being given a terminal diagnosis with only a few weeks to live, Jane dug up research, some decades old, in her quest to survive. Rather than aiming to cure cancer, which in many cases is unachievable, Jane's approach was to stop it growing. Remarkably her approach not only stopped it growing, it disappeared altogether. There are now clinics following her protocol, achieving remarkable successes. This book is a game-changing new dawn in the treatment of cancer. An international publishing