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Epigenetic Mechanisms in Cancer

Epigenetic Mechanisms in Cancer
  • Author : Sabita Saldanha
  • Publsiher : Academic Press
  • Release : 16 November 2017
  • ISBN : 0128134607
  • Pages : 392 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKEpigenetic Mechanisms in Cancer

Summary:
Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences in childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes. Offers broad coverage that is applicable to audiences in various area of cancer research - population studies, diagnostics, prognosis, prediction, therapy, risk, etc. Provides critical review analysis of the topics that will clarify and delineate the potential roles of epigenetic signatures in cancer management Covers basic, as well as, clinical areas of epigenetic mechanisms in tumorigenesis Features contributions by leading experts in the field Provides comprehensive coverage of current epigenetic signatures involved in the etiology of various cancers and miRNAs


Epigenetic Mechanisms in Cancer

Epigenetic Mechanisms in Cancer
  • Author : Sabita Saldanha
  • Publisher : Academic Press
  • Release : 16 November 2017
GET THIS BOOKEpigenetic Mechanisms in Cancer

Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences in childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of


Epigenetic Cancer Therapy

Epigenetic Cancer Therapy
  • Author : Steven Gray
  • Publisher : Academic Press
  • Release : 01 July 2015
GET THIS BOOKEpigenetic Cancer Therapy

Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector. The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).


Epigenetics of Cancer Prevention

Epigenetics of Cancer Prevention
  • Author : Anupam Bishayee,Deepak Bhatia
  • Publisher : Academic Press
  • Release : 07 December 2018
GET THIS BOOKEpigenetics of Cancer Prevention

Epigenetics of Cancer Prevention is the first of its kind to look at epigenetics and chemoprevention together. Although there are numerous scientific data available on how epigenetics can lead to cancer and separately how chemoprevention can be beneficial in the treatment or in improving quality of life, together they will set an advanced understanding for the reader in this upcoming field of chemoprevention influencing epigenetics. This book discusses molecular epigenetic targets of natural products, such as green tea polyphenols, curcumin


The Molecular Basis of Human Cancer

The Molecular Basis of Human Cancer
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher : Springer Science & Business Media
  • Release : 10 August 2001
GET THIS BOOKThe Molecular Basis of Human Cancer

Internationally renowned basic and clinical scientists provide an account of our best current understanding of the genetics of cancer. These authoritative contributors describe in detail each of the known molecular mechanisms governing neoplastic transformation in the breast, prostate, lung, liver, colon, and skin, and in the leukemias and lymphomas. Their discussion illuminates both recent developments and established concepts in epidemiology, molecular techniques, oncogenesis, and mutation mechanisms, as well as the chemical, viral, and physical mechanisms in cancer induction.


New Aspects in Molecular and Cellular Mechanisms of Human Carcinogenesis

New Aspects in Molecular and Cellular Mechanisms of Human Carcinogenesis
  • Author : Dmitry Bulgin
  • Publisher : BoD – Books on Demand
  • Release : 02 March 2016
GET THIS BOOKNew Aspects in Molecular and Cellular Mechanisms of Human Carcinogenesis

Written by an international team of experts in the field of human carcinogenesis, this book discusses recent advances in cancer research, which include the following topics: basic molecular and cellular mechanisms behind cancer growth, new approaches in cancer therapy, and cancer diagnostic. The book serves as a useful source of reference for cancer biologists, medical doctors, and clinical researchers in the fields of cancer diagnosis, prevention, and treatment.


Drug Discovery in Cancer Epigenetics

Drug Discovery in Cancer Epigenetics
  • Author : Gerda Egger,Paola Arimondo
  • Publisher : Academic Press
  • Release : 19 November 2015
GET THIS BOOKDrug Discovery in Cancer Epigenetics

Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy prediction. Most importantly, epigenetic modifications are reversible and epigenetic players are found mutated in different cancers; therefore, they provide attractive therapeutic targets. There has been great interest in developing and testing epigenetic drugs, which inhibit DNA methyltransferases, histone modifying enzymes or chromatin


Human Papillomavirus

Human Papillomavirus
  • Author : Rajamanickam Rajkumar
  • Publisher : BoD – Books on Demand
  • Release : 13 July 2016
GET THIS BOOKHuman Papillomavirus

This book is a feast of knowledge, yet a balanced diet of healthy foods. There are high values of rich essential nutrients from top-quality medical research. But they are made easily digestible and absorbable, even by health care providers and planners, working in resource-limited settings, in all parts of the world, through social implications and community applications. All the chapters are value-added master pieces. The book would serve both as a scientific reference guide and a practical work manual. The


Epigenetic Advancements in Cancer

Epigenetic Advancements in Cancer
  • Author : Manoj K. Mishra,Kumar S. Bishnupuri
  • Publisher : Springer
  • Release : 04 May 2016
GET THIS BOOKEpigenetic Advancements in Cancer

This volume explores the epigenetic alterations and their association with various human cancers. Considering one of human cancer as an example, individual chapters are focused on defining the role of epigenetic regulators and underlying mechanisms in cancer growth and progression. Epigenetic alteration including DNA methylation, histone modification, nucleosome positioning and non-coding RNAs expression are involved in a complex network of regulating expression of oncogenes and tumor suppressor genes and constitute an important event of the multistep process of carcinogenesis. Recent


Cancer Epigenetics

Cancer Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : CRC Press
  • Release : 19 September 2008
GET THIS BOOKCancer Epigenetics

During the past few decades, it has become increasingly apparent that heredity is not the sole determining factor in disease development, such as cancer. This landmark work covers a wide array of aspects in the relatively new area of epigenetics, ranging from its role in the basic mechanisms of tumorigenesis, to the newest epigenetic drugs being developed and used for cancer therapy. Cancer Epigenetics presents in-depth discussions of DNA methylation alterations, histone and RNA modifications, and nucleosome remodeling, which are


Epigenetics and Cancer

Epigenetics and Cancer
  • Author : Fazlul H. Sarkar
  • Publisher : Springer Science & Business Media
  • Release : 29 May 2013
GET THIS BOOKEpigenetics and Cancer

Overall, this book illustrates the complexities of the regulation and deregulation of genes mediated through epigenetics in the development and progression of human malignancies. All the articles have been carefully chosen to represent several cancer systems with state of our knowledge on the role of epigenetic deregulation of microRNAs (miRNAs) and their target mRNAs along with epigenetic deregulation of mRNAs. This book also illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in modulating the epigenetic


Gynecological Cancers

Gynecological Cancers
  • Author : Antonio Giordano,Marcella Macaluso
  • Publisher : Springer
  • Release : 12 July 2016
GET THIS BOOKGynecological Cancers

Facilitating the collaboration between the basic, translational, and clinical sciences, this book provides an overview of the genetic and epigenetic mechanisms underlying the formation and progression of gynecological cancers. Gynecological Cancers: Genetic and Epigenetic Targets and Drug Development gathers all of the molecular and cellular aspects of gynecological cancer together within one volume, providing detailed and up-to-date information on the etiology, diagnosis, and treatment of gynecological cancers. Gynecological Cancers: Genetic and Epigenetic Targets and Drug Development ​also discusses the racial


Nutrition, Epigenetic Mechanisms, and Human Disease

Nutrition, Epigenetic Mechanisms, and Human Disease
  • Author : Nilanjana Maulik,Gautam Maulik
  • Publisher : CRC Press
  • Release : 03 December 2010
GET THIS BOOKNutrition, Epigenetic Mechanisms, and Human Disease

As nutrition research is shifting its focus from epidemiology and physiology to effects of nutrients at the molecular level, a uniquely tailored diet that corresponds to the demands of our genetic signature is emerging as an indispensable need. Using high-throughput genomic tools, nutrigenomics unravels the influence of micro- and macronutrients as


Epigenetics in Human Disease

Epigenetics in Human Disease
  • Author : Trygve O. Tollefsbol
  • Publisher : Academic Press
  • Release : 02 March 2021
GET THIS BOOKEpigenetics in Human Disease

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable,


Neuroblastoma

Neuroblastoma
  • Author : Chandrika Gowda
  • Publisher : BoD – Books on Demand
  • Release : 25 October 2017
GET THIS BOOKNeuroblastoma

Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including


Prognostic Epigenetics

Prognostic Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 01 November 2019
GET THIS BOOKPrognostic Epigenetics

This volume provides comprehensive information on how mapping an individual’s epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can