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Essential Enzyme Kinetics

Essential Enzyme Kinetics
  • Author : Daniel L. Purich
  • Publsiher : Academic Press
  • Release : 01 June 2020
  • ISBN : 0128218096
  • Pages : 425 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKEssential Enzyme Kinetics

Summary:
Essential Enzyme Kinetics: A Textbook for Molecular Life Scientists describes the theoretical basis and best-practice approaches for using initial-rate, fast reaction, and kinetic isotope effect experiments to define enzyme catalysis. Because a detailed knowledge of enzyme transition-states is the main driver for the rational design of slow, tight-binding inhibitors destined to become tomorrow's small-molecule drugs, Essential Enzyme Kinetics is the must-have reference for chemists, biochemists, and pharmacologists intent on pursuing careers in Big Pharma. Given the interdisciplinary nature of contemporary drug development, this book provides a lucid short-course that will also benefit nonspecialists seeking to understand the scope and reach of modern enzyme kinetics. Provides practical information about how to work with enzymes and design experiments to identify new inhibitors or activators Includes detailed step-by-step derivations of rate equations, showing tried-and-true ways to confirm that the equations obtained are correct Arranged for use both as a desk reference (with over 200 equations and more than 400 key references) or as a textbook (with 8-10 problems/exercises at the end of each chapter)