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Gap Junctions in the Brain

Gap Junctions in the Brain
  • Author : Ekrem Dere
  • Publsiher : Academic Press
  • Release : 12 December 2012
  • ISBN : 0124159273
  • Pages : 304 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKGap Junctions in the Brain

Summary:
Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants. Serves as the most current and comprehensive reference available covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain Chapters summarize knowledge of the basic physiology of gap junctions in the brain, as well as of human disease conditions associated with mutations in single gap junction connexin genes Includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants


Gap Junctions in the Brain

Gap Junctions in the Brain
  • Author : Ekrem Dere
  • Publisher : Academic Press
  • Release : 12 December 2012
GET THIS BOOKGap Junctions in the Brain

Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human

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Gap Junctions in the Nervous System

Gap Junctions in the Nervous System
  • Author : David C. Spray,Rolf Dermietzel
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOKGap Junctions in the Nervous System

This book deals with the types of gap junction proteins (connexins) and their distribution within the nervous system, the physiological properties of channels formed of each connexin, and the role of gap junction channels in functions of normal and pathological brain and peripheral nerve. Although glial tissue is emphasized, additional groups of chapters deal with neurons in the central nervous system and with the retina.

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Gap Junctions in the Brain

Gap Junctions in the Brain
  • Author : Ekrem Dere
  • Publisher : Academic Press
  • Release : 22 May 2022
GET THIS BOOKGap Junctions in the Brain

Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human

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The Blood Brain Barrier (BBB)

The Blood Brain Barrier (BBB)
  • Author : Gert Fricker,Melanie Ott,Anne Mahringer
  • Publisher : Springer
  • Release : 24 October 2014
GET THIS BOOKThe Blood Brain Barrier (BBB)

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series

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Gap Junction Channels and Hemichannels

Gap Junction Channels and Hemichannels
  • Author : Donglin Bai,Juan C. Sáez
  • Publisher : CRC Press
  • Release : 05 August 2016
GET THIS BOOKGap Junction Channels and Hemichannels

Gap junction channels are a group of intercellular channels expressed in tissues and organs to synchronize many physiological processes. A gap junction channel is formed by the docking of two hemichannels, and each hemichannel is a hexamer of connexins. The field of gap junction channel and hemichannel research has recently exploded and became one of the most active areas of cell biology. Numerous novel approaches and techniques have been developed, but there is no single book dedicated to the unique

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Connectivity and Functional Specialization in the Brain

Connectivity and Functional Specialization in the Brain
  • Author : Thomas Heinbockel,Yongxia Zhou
  • Publisher : BoD – Books on Demand
  • Release : 02 June 2021
GET THIS BOOKConnectivity and Functional Specialization in the Brain

‘Connectivity and Functional Specialization in the Brain’ is a topic that describes nerve cells in terms of their anatomical and functional connections. The term connectome refers to a comprehensive map of neural connections, like a wiring diagram of an organism’s nervous system. Connectomics, the study of connectomes, can be applied to individual neurons and their synaptic connections, as well as to connections between neuronal populations or to functional and structural connectivity of different brain regions. This book addresses neural

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Discovering the Brain

Discovering the Brain
  • Author : National Academy of Sciences,Institute of Medicine,Sandra Ackerman
  • Publisher : National Academies Press
  • Release : 01 January 1992
GET THIS BOOKDiscovering the Brain

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the

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Connexin Cell Communication Channels

Connexin Cell Communication Channels
  • Author : Ernesto Oviedo-Orta,Brenda R. Kwak,William Howard Evans
  • Publisher : CRC Press
  • Release : 22 March 2013
GET THIS BOOKConnexin Cell Communication Channels

Plasma membrane-associated channels known as gap junctions, along with their protein building blocks—connexins—have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field. The book first provides a historical overview of the discovery of these

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PH and Brain Function

PH and Brain Function
  • Author : Kai Kaila,Bruce R. Ransom
  • Publisher : John Wiley & Sons
  • Release : 15 September 1998
GET THIS BOOKPH and Brain Function

"PH and Brain Function offers thorough coverage of this increasingly important area of research, beginning with the fundamental concepts, which include methodological and theoretical issues such as the measurement of pH and the concept of pH in neurobiology. It explores aspects of regulation and modulation of intracellular pH in brain cells, surveys the changes in pH that occur with neural activity and how these changes affect neural activity, and discusses the role of pH in the pathophysiology of neurological diseases." "

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The Endothelium

The Endothelium
  • Author : Michel Félétou
  • Publisher : Morgan & Claypool Publishers
  • Release : 22 May 2022
GET THIS BOOKThe Endothelium

"The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen

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Intercellular Communication in the Nervous System

Intercellular Communication in the Nervous System
  • Author : Robert Malenka
  • Publisher : Academic Press
  • Release : 22 May 2010
GET THIS BOOKIntercellular Communication in the Nervous System

Intercellular communication is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their environment is the basis of growth and development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, diabetes, and neurological and psychiatric disorders. There is substantial drug development concentrating on this and intercellular communication is the

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