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Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Green Approaches in Medicinal Chemistry for Sustainable Drug Design
  • Author : Bimal K. Banik
  • Publsiher : Advances in Green Chemistry
  • Release : 01 April 2020
  • ISBN : 0128175923
  • Pages : 610 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKGreen Approaches in Medicinal Chemistry for Sustainable Drug Design

Summary:
Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6.


Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Green Approaches in Medicinal Chemistry for Sustainable Drug Design
  • Author : Bimal K. Banik
  • Publisher : Advances in Green Chemistry
  • Release : 01 April 2020
GET THIS BOOKGreen Approaches in Medicinal Chemistry for Sustainable Drug Design

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and


Contemporary Chemical Approaches for Green and Sustainable Drugs

Contemporary Chemical Approaches for Green and Sustainable Drugs
  • Author : Marianna Torok
  • Publisher : Elsevier
  • Release : 15 July 2021
GET THIS BOOKContemporary Chemical Approaches for Green and Sustainable Drugs

The design, discovery, development and use of medicinal agents produces a whole range of environmental contaminants which have a damaging ecological impact. By acknowledging and addressing these issues, chemists can take preventative steps at multiple stages in the process, from using computational models and selecting green solvents, to designing for degradation and creating new remediation tools. Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate such sustainable approaches into their work. After


Green Chemistry in the Pharmaceutical Industry

Green Chemistry in the Pharmaceutical Industry
  • Author : Peter J. Dunn,Andrew Wells,Michael T. Williams
  • Publisher : John Wiley & Sons
  • Release : 02 February 2010
GET THIS BOOKGreen Chemistry in the Pharmaceutical Industry

Edited by three of the world's leading pharmaceutical scientists, this is the first book on this important and hot topic, containing much previously unpublished information. As such, it covers all aspects of green chemistry in the pharmaceutical industry, from simple molecules to complex proteins, and from drug discovery to the fate of pharmaceuticals in the environment. Furthermore, this ready reference contains several convincing case studies from industry, such as Taxol, Pregabalin and Crestor, illustrating how this multidisciplinary approach has yielded


Green Sustainable Process for Chemical and Environmental Engineering and Science

Green Sustainable Process for Chemical and Environmental Engineering and Science
  • Author : Dr. Inamuddin,Rajender Boddula,Abdullah M. Asiri
  • Publisher : Elsevier
  • Release : 19 June 2020
GET THIS BOOKGreen Sustainable Process for Chemical and Environmental Engineering and Science

Green Sustainable Process for Chemical and Environmental Engineering and Science: Sonochemical Organic Synthesis focuses on purification and extraction of organic, biological, and medicinal compounds using sonochemistry. It provides readers with an understanding of green ultrasound-assisted chemical synthesis for industrial applications. This book systematically explores the application of ultrasound in organic synthesis of all types and includes stereoselectivity, regioselectivity, oxidations, reductions, protection, deprotection, additions, condensation, coupling, C-X bond formation, named reactions, heterocyclics, biological drugs, and fluoroorganics over conventional techniques. A brief


The Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry
  • Author : Camille Georges Wermuth,David Aldous,Pierre Raboisson,Didier Rognan
  • Publisher : Elsevier
  • Release : 01 July 2015
GET THIS BOOKThe Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to


Green Synthetic Approaches for Biologically Relevant Heterocycles

Green Synthetic Approaches for Biologically Relevant Heterocycles
  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release : 17 November 2014
GET THIS BOOKGreen Synthetic Approaches for Biologically Relevant Heterocycles

Green Synthetic Approaches for Biologically Relevant Heterocycles reviews this significant group of organic compounds within the context of sustainable methods and processes. Each clearly structured chapter features in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles classified on the basis of ring-size and/or presence of heteratoms(s). Techniques covered include microwave heating, ultrasound, ionic liquids, solid phase, solvent-free, heterogeneous catalysis, and aqueous media, along with multi-component reaction strategies. This book also integrates


Green and Sustainable Pharmacy

Green and Sustainable Pharmacy
  • Author : Klaus Kümmerer,Maximilian Hempel
  • Publisher : Springer Science & Business Media
  • Release : 16 June 2010
GET THIS BOOKGreen and Sustainable Pharmacy

Within recent years pharmaceuticals have come into focus as contaminants of the environment (see for example Kümmerer, K. editor: Pharmaceuticals in the Environment). At the same time the issue of sustainable chemistry gained momentum. Bringing both together would result in sustainable pharmacy. Sustainable pharmacy is a totally new issue and approach. It addresses environmental, economical and social aspects of pharmacy. In the present stage the focus will be on environmental issues along the whole lifecycle of a pharmaceutical entity.


Medicinal Chemistry Approaches to Tuberculosis and Trypanosomiasis

Medicinal Chemistry Approaches to Tuberculosis and Trypanosomiasis
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 06 September 2019
GET THIS BOOKMedicinal Chemistry Approaches to Tuberculosis and Trypanosomiasis

Some of the more recent efforts in tuberculosis (TB) and trypanosomiasis drug discovery from both Product Development Partnerships (PDPs) and academia are highlighted in this this volume. Drug discovery approaches include both target- and phenotypic whole cell screening- approaches. Regarding the latter, mechanism of action studies through target identification are also illustrated. Provides an overview of the status of some of the current novel compounds in development as well as new emerging treatment options targeting novel mechanisms of action Identification


Green and Sustainable Medicinal Chemistry

Green and Sustainable Medicinal Chemistry
  • Author : Louise Summerton,Helen F Sneddon,Leonie C Jones,James H Clark
  • Publisher : Royal Society of Chemistry
  • Release : 08 March 2016
GET THIS BOOKGreen and Sustainable Medicinal Chemistry

Pharmaceutical manufacturing was one of the first industries to recognize the importance of green chemistry, with pioneering work including green chemistry metrics and alternative solvents and reagents. Today, other topical factors also have to be taken into consideration, such as rapidly depleting resources, high energy costs and new legislation. This book addresses current challenges in modern green chemical technologies and sustainability thinking. It encompasses a broad range of topics covered by the CHEM21 project – Europe’s largest public-private partnership project


Green Chemistry

Green Chemistry
  • Author : Hosam El-Din M. Saleh,Martin Koller
  • Publisher : BoD – Books on Demand
  • Release : 28 February 2018
GET THIS BOOKGreen Chemistry

To an increasing extent, "green chemistry" is a new chemical and engineering approach of chemistry and engineering, dedicated to make manufacturing processes and our world as a whole more sustainable world with a growing tendency. "Green chemistry" approaches are based on ecofriendly technologies, aiming to reduce or eliminate the use of solvents, or render them efficient and safer. Moreover, this scientific field is devoted to reduction or elimination of prevailing environmental and health threats, which typically accompany chemical products and


Computational Drug Design

Computational Drug Design
  • Author : D. C. Young
  • Publisher : John Wiley & Sons
  • Release : 28 January 2009
GET THIS BOOKComputational Drug Design

Helps you choose the right computational tools and techniques to meet your drug design goals Computational Drug Design covers all of the major computational drug design techniques in use today, focusing on the process that pharmaceutical chemists employ to design a new drug molecule. The discussions of which computational tools to use and when and how to use them are all based on typical pharmaceutical industry drug design processes. Following an introduction, the book is divided into three parts: Part


Sustainable Synthesis of Pharmaceuticals

Sustainable Synthesis of Pharmaceuticals
  • Author : Mariette M. Pereira,Mario J. F. Calvete
  • Publisher : Royal Society of Chemistry
  • Release : 26 March 2018
GET THIS BOOKSustainable Synthesis of Pharmaceuticals

There is a growing interest in the development of sustainable processes for the synthesis of pharmaceuticals and this book bridges the divide between industrial examples and the fundamental chemistry. It explains the basic principles of using transition metal catalysis with several green approaches for the synthesis of pharmaceuticals. The topic is an important one for green chemistry and the chapters in this book on hydroformylation, green oxidation and olefin metathesis will also be of interest to both medicinal and organic


Green and Sustainable Medicinal Chemistry

Green and Sustainable Medicinal Chemistry
  • Author : Louise Summerton,Helen F Sneddon,Leonie C Jones,James H Clark
  • Publisher : Royal Society of Chemistry
  • Release : 08 March 2016
GET THIS BOOKGreen and Sustainable Medicinal Chemistry

Pharmaceutical manufacturing was one of the first industries to recognize the importance of green chemistry, with pioneering work including green chemistry metrics and alternative solvents and reagents. Today, other topical factors also have to be taken into consideration, such as rapidly depleting resources, high energy costs and new legislation. This book addresses current challenges in modern green chemical technologies and sustainability thinking. It encompasses a broad range of topics covered by the CHEM21 project – Europe’s largest public-private partnership project


Green Chemistry and Biodiversity

Green Chemistry and Biodiversity
  • Author : Cristobal N. Aguilar,Suresh C. Ameta,A. K. Haghi
  • Publisher : CRC Press
  • Release : 06 December 2019
GET THIS BOOKGreen Chemistry and Biodiversity

Green Chemistry and Biodiversity: Principles, Techniques, and Correlations reports on new approaches to designing chemicals and chemical transformations that are beneficial for human health and the environment, a continuing emerging important field of study. This volume provides a collection of innovative research on the development of alternative sustainable technologies, taking a broad view of the subject and integrating a wide variety of approaches. With a focus on the interdisciplinary applications of green chemistry and biodiversity, this volume will be a


Chemistry and Chemical Engineering for Sustainable Development

Chemistry and Chemical Engineering for Sustainable Development
  • Author : Miguel A. Esteso,Ana Cristina Faria Ribeiro,A. K. Haghi
  • Publisher : CRC Press
  • Release : 26 November 2020
GET THIS BOOKChemistry and Chemical Engineering for Sustainable Development

The world faces significant challenges as population and consumption continue to grow while nonrenewable fossil fuels and other raw materials are depleted at ever-increasing rates. This volume takes a technical approach that addresses these issues using green design and analysis. It brings together innovative research, new concepts, and novel developments in the application of new tools for chemical and materials engineers. It is an immensely research-oriented, comprehensive, and practical work that focuses on the use of applied concepts to enhance