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Introductory Review on Sirtuins in Biology Aging and Disease

Introductory Review on Sirtuins in Biology  Aging  and Disease
  • Author : Leonard Guarente
  • Publsiher : Academic Press
  • Release : 20 April 2018
  • ISBN : 012813500X
  • Pages : 220 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKIntroductory Review on Sirtuins in Biology Aging and Disease

Summary:
Introductory Review on Sirtuins in Biology and Disease provides key insights for scientists and advanced students who need to understand sirtuins and the current research in this field. This book is ideal for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses. Sirtuins are a diverse family of proteins, with several members in mammals. The functional diversity of sirtuins is rather broad, and they have been implicated in various central biological processes. Thus, they are also highly relevant in the context of various human diseases, from cancer to neurodegeneration. Covers both the general and specific aspects of sirtuin proteins and their role in biology, aging and disease Presents a top quality collection of leading experts who contribute on a wide range of sirtuin-related topics Ideal resource for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses


Introductory Review on Sirtuins in Biology, Aging, and Disease

Introductory Review on Sirtuins in Biology, Aging, and Disease
  • Author : Leonard Guarente,Raul Mostoslavsky,Aleksey Kazantsev
  • Publisher : Academic Press
  • Release : 20 April 2018
GET THIS BOOKIntroductory Review on Sirtuins in Biology, Aging, and Disease

Introductory Review on Sirtuins in Biology and Disease provides key insights for scientists and advanced students who need to understand sirtuins and the current research in this field. This book is ideal for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses. Sirtuins are a diverse family of proteins, with several members in mammals. The functional diversity of sirtuins is rather broad, and they have been implicated in various central biological processes. Thus,

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Food and Lifestyle in Health and Disease

Food and Lifestyle in Health and Disease
  • Author : Chuong Pham-Huy,Bruno Pham Huy
  • Publisher : CRC Press
  • Release : 25 April 2022
GET THIS BOOKFood and Lifestyle in Health and Disease

This book discusses various types of food and lifestyles for the prevention and treatment of diseases and disorders, including cardiovascular disorders, cancers, neurodegenerative diseases, diabetes, hypertension, and obesity. Discusses influences of environmental pollution, synergistic effects of different foods, and synergy of foods with physical activity or medicine. Provides examples of plant source foods, animal source foods, fungal source foods and explains their roles in human health and disease. Links the relationships between food, lifestyle and health.

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Sirtuin Biology in Medicine

Sirtuin Biology in Medicine
  • Author : Kenneth Maiese
  • Publisher : Academic Press
  • Release : 04 March 2021
GET THIS BOOKSirtuin Biology in Medicine

Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease provides a fascinating and in-depth analysis of sirtuins in the body during normal physiology as well during disease highlighting the targeting of sirtuin-controlled pathways for the development of innovative, efficacious, and safe therapeutic strategies for multiple disorders in the body that ultimately can affect lifespan extension. Sirtuins are expressed throughout the body, have broad biological effects, and can significantly impact both cellular survival and longevity during

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GeNeDis 2020

GeNeDis 2020
  • Author : Panayiotis Vlamos
  • Publisher : Springer Nature
  • Release : 12 January 2022
GET THIS BOOKGeNeDis 2020

The 4th World Congress on Genetics, Geriatrics, and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The relation between genetics and its effect on several diseases are thoroughly examined in this volume. This volume focuses on the sessions from the conference on

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The Healthspan Solution

The Healthspan Solution
  • Author : Raymond J. Cronise,Julieanna Hever
  • Publisher : Penguin
  • Release : 17 December 2019
GET THIS BOOKThe Healthspan Solution

Increase your lifespan and optimize your health with plant-based recipes for a longer, more vibrant life. Authors and leading plant-based nutrition experts Julieanna Hever and Ray Cronise have spent over a decade researching diet and nutrition, analyzing longevity studies, and helping their clients achieve sustainable, lasting health benefits by adopting a whole food, plant-based diet. In The Healthspan Solution, they share the simple and effective diet that has allowed their clients to lose weight, reverse disease, reduce or eliminate medication

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Oxidative Stress, Antioxidants, Transcription Factors, and Assimilation of Signal Transduction Pathways in Obesity-Related Disorders

Oxidative Stress, Antioxidants, Transcription Factors, and Assimilation of Signal Transduction Pathways in Obesity-Related Disorders
  • Author : Terry D. Hinds, Jr,David E. Stec,Barbara Wegiel
  • Publisher : Frontiers Media SA
  • Release : 21 October 2021
GET THIS BOOKOxidative Stress, Antioxidants, Transcription Factors, and Assimilation of Signal Transduction Pathways in Obesity-Related Disorders

Topic Editors Terry Hinds and David Stec have submitted patents related to bilirubin and obesity related disorders. The other Topic Editor declare no potential conflicts of interest with regards to the Research Topic subject.

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Handbook of the Biology of Aging

Handbook of the Biology of Aging
  • Author : Matt Kaeberlein,George Martin
  • Publisher : Academic Press
  • Release : 20 August 2015
GET THIS BOOKHandbook of the Biology of Aging

Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to

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Epigenetics and Dermatology

Epigenetics and Dermatology
  • Author : Qianjin Lu,Christopher C. Chang,Bruce C. Richardson
  • Publisher : Academic Press
  • Release : 16 February 2015
GET THIS BOOKEpigenetics and Dermatology

Epigenetics and Dermatology explores the role of epigenetics in the pathogenesis of autoimmune-related skin diseases and skin cancer. Leading contributors cover common and uncommon skin conditions in which extensive epigenetic research has been done. They explain how environmental exposures (chemicals, drugs, sunlight, diet, stress, smoking, infection, etc.) in all stages of life (from a fetus in-utero to an elderly person) may result in epigenetic changes that lead to development of some skin diseases in life. They also discuss the possibilities

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Lifespan

Lifespan
  • Author : David A. Sinclair,Matthew D. LaPlante
  • Publisher : Atria Books
  • Release : 10 September 2019
GET THIS BOOKLifespan

A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory

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Molecular Biology of Aging

Molecular Biology of Aging
  • Author : Leonard Guarente,Linda Partridge,Douglas C. Wallace
  • Publisher : CSHL Press
  • Release : 22 May 2022
GET THIS BOOKMolecular Biology of Aging

This volume covers the major threads in the molecular genetics of aging, including genes that regulate aging, causes of aging, evolutionary theories of aging, and the relationship between diet and aging. Among specific topics covered are calorie restriction, mitochondria, sirtuins, telomeres, stem cells, and cancer.

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Senescence and Senescence-Related Disorders

Senescence and Senescence-Related Disorders
  • Author : Wang Zhiwei,Hiroyuki Inuzuka
  • Publisher : BoD – Books on Demand
  • Release : 20 February 2013
GET THIS BOOKSenescence and Senescence-Related Disorders

Senescence is a biological process that causes a progressive deterioration of structure and function of all organs chronologically. Recent studies have revealed the detailed molecular mechanisms of senescence using cell culture system and experimental organisms. It is thought that senescence is a potential cause for the development of various age-related disorders such as cancer, cardiovascular and neurodegenerative disorders. This book discusses in detail senescence and its related diseases by distinguished researchers and practicing clinicians. The cumulative knowledge from the studies

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Aging

Aging
  • Author : Shamim I. Ahmad
  • Publisher : CRC Press
  • Release : 30 October 2017
GET THIS BOOKAging

This book is a detailed and comprehensive synthesis of the scientific study of aging. Dozens of contributions from leading scholars review various theories of aging, and molecular, cellular, biochemical and microbial aspects of aging, among just a few of the topics included. Authoritative, wide ranging and thorough, this book will act as a source for experimental design, a comprehensive description of age related diseases, and provide information of the latest molecular theories underlying their causes. Additionally, it will target industries

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Reviews on Biomarker Studies in Aging and Anti-Aging Research

Reviews on Biomarker Studies in Aging and Anti-Aging Research
  • Author : Paul C. Guest
  • Publisher : Springer Nature
  • Release : 06 September 2019
GET THIS BOOKReviews on Biomarker Studies in Aging and Anti-Aging Research

Using both epidemiological and model organism approaches, we have gained new insights into the physiological and molecular aspects of aging, which has led to significant advancements in potential anti-aging strategies. Reviews on Biomarker Studies in Aging and Anti-Aging Research presents a series of reviews in various aspects of aging and age-related disease research along with several methods which have shown progress as potential anti-aging approaches. The book is aimed at researchers in the areas of aging and chronic disease, as

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Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging

Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging
  • Author : Sandeep Kumar Singh,Chih Li Lin,Shailendra Kumar Mishra
  • Publisher : Academic Press
  • Release : 15 May 2022
GET THIS BOOKAnti-Aging Drug Discovery on the Basis of Hallmarks of Aging

Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals. Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies, providing comprehensive foundational knowledge of

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Sirtuins in Biology and Disease

Sirtuins in Biology and Disease
  • Author : Tiago F. Outeiro,Aleksey G. Kazantsev
  • Publisher : Frontiers E-books
  • Release : 22 May 2022
GET THIS BOOKSirtuins in Biology and Disease

Sirtuins comprise a family of NAD+-dependent enzymes that have been shown to impact longevity in a number of eukaryotic organisms. Sir2 (Silent Information Regulator 2) was the first sirtuin protein discovered. The discovery that Sir2 requires NAD+ for its activity suggested a link between Sir2 activity and the phenomenon of caloric restriction in prolonging longevity. This link was strengthened by the observation that lifespan extension by caloric restriction requires Sir2 protein. Under conditions of caloric restriction, NAD+ levels are high,

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