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Mesenchymal Stem Cells and Skeletal Regeneration

Mesenchymal Stem Cells and Skeletal Regeneration
  • Author : Peter Giannoudis
  • Publsiher : Academic Press
  • Release : 20 February 2013
  • ISBN : 0124081312
  • Pages : 70 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKMesenchymal Stem Cells and Skeletal Regeneration

Summary:
This book covers our current understanding of the role of mesenchymal stem cells (MSCs) and other mesenchymal progenitors in skeletal regeneration, encompassing bone, cartilage and whole joint regeneration. The expansion reflects developments in the field to include data on the use of MSCs in drug development, growth factors, scaffolds and biomechanical manipulations for skeletal trauma and diseases, including osteoporosis and arthritis. Written for an audience of clinicians and young researchers who are exposed to MSCs in their work, this work summarizes recent findings pertaining to the definition and characterization of MSCs in skeletal tissues and discusses the mechanisms of their actions in regeneration of bone in vivo. The authors describe recent findings pertaining to the efficacy of MSC therapies in animal models and in human clinical trials and bring together literature showing that the ways MSCs are extracted, expanded and implanted can considerably affect bone formation outcomes. Finally, it presents the latest knowledge on the nature of native MSCs in skeletal tissues, which provide a platform for novel in situ tissue regeneration approaches for systemic bone disease such as osteoporosis. Focuses specifically on the use of stem cells in skeletal tissue generation for a broad audience of stem cell, cancer, and bone biologists, orthopedists, oncologists, and regenerative medicine specialists Provides a short historical ‘detour’ and foundational information on founding concepts, discoveries and personalities in MSC research Assists a new generation of scientists and clinicians in digesting the multitude of journal articles on the topic by providing easily-absorbed and condensed foundational context


Mesenchymal Stem Cells and Skeletal Regeneration

Mesenchymal Stem Cells and Skeletal Regeneration
  • Author : Peter Giannoudis,Elena Jones,Xuebin Yang,Dennis Mcgonagle
  • Publisher : Academic Press
  • Release : 20 February 2013
GET THIS BOOKMesenchymal Stem Cells and Skeletal Regeneration

This book covers our current understanding of the role of mesenchymal stem cells (MSCs) and other mesenchymal progenitors in skeletal regeneration, encompassing bone, cartilage and whole joint regeneration. The expansion reflects developments in the field to include data on the use of MSCs in drug development, growth factors, scaffolds and biomechanical manipulations for skeletal trauma and diseases, including osteoporosis and arthritis. Written for an audience of clinicians and young researchers who are exposed to MSCs in their work, this work

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Mesenchymal Stem Cells and Skeletal Regeneration

Mesenchymal Stem Cells and Skeletal Regeneration
  • Author : Anonim
  • Publisher : Anonim
  • Release : 27 October 2021
GET THIS BOOKMesenchymal Stem Cells and Skeletal Regeneration

This book covers our current understanding of the role of mesenchymal stem cells (MSCs) and other mesenchymal progenitors in skeletal regeneration, encompassing bone, cartilage and whole joint regeneration. The expansion reflects developments in the field to include data on the use of MSCs in drug development, growth factors, scaffolds and biomechanical manipulations for skeletal trauma and diseases, including osteoporosis and arthritis. Written for an audience of clinicians and young researchers who are exposed to MSCs in their work, this work

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Bone Regeneration and Repair

Bone Regeneration and Repair
  • Author : Jay R. Lieberman,Gary E. Friedlaender
  • Publisher : Springer Science & Business Media
  • Release : 27 October 2007
GET THIS BOOKBone Regeneration and Repair

This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.

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Mesenchymal Stem Cells in Human Health and Diseases

Mesenchymal Stem Cells in Human Health and Diseases
  • Author : Ahmed H.K. El-Hashash
  • Publisher : Academic Press
  • Release : 07 January 2020
GET THIS BOOKMesenchymal Stem Cells in Human Health and Diseases

Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural

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Vascularization

Vascularization
  • Author : Eric M. Brey
  • Publisher : CRC Press
  • Release : 07 August 2014
GET THIS BOOKVascularization

A Complex and Growing Field The study of vascularization in tissue engineering and regenerative medicine (TERM) and its applications is an emerging field that could revolutionize medical approaches for organ and tissue replacement, reconstruction, and regeneration. Designed specifically for researchers in TERM fields, Vascularization: Regenerative Medicine and Tissue Engineering provides a broad overview of vascularization in TERM applications. This text summarizes research in several areas, and includes contributions from leading experts in the field. It defines the difficulties associated with

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Advanced Techniques in Bone Regeneration

Advanced Techniques in Bone Regeneration
  • Author : Alessandro Rozim Zorzi,João Batista de Miranda
  • Publisher : BoD – Books on Demand
  • Release : 31 August 2016
GET THIS BOOKAdvanced Techniques in Bone Regeneration

Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.

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Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
  • Author : Lucas G. Chase,Mohan C Vemuri
  • Publisher : Springer Science & Business Media
  • Release : 12 December 2012
GET THIS BOOKMesenchymal Stem Cell Therapy

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host

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Muscular Dystrophy

Muscular Dystrophy
  • Author : Gisela Gaina
  • Publisher : BoD – Books on Demand
  • Release : 23 December 2020
GET THIS BOOKMuscular Dystrophy

Muscular Dystrophy - Research Update and Therapeutic Strategies is for students, researchers, and clinicians interested in muscular dystrophies who want to improve their knowledge of these complex genetic diseases. The book includes information about the genetics of various types of muscular dystrophies as well as explores new and current therapeutic strategies that aim to ameliorate symptoms and improve patients’ quality of life and life expectancy. In addition, this book reviews information on current clinical trials for muscular dystrophies and presents

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Bone and Cartilage Regeneration

Bone and Cartilage Regeneration
  • Author : Phuc Van Pham
  • Publisher : Springer
  • Release : 24 January 2017
GET THIS BOOKBone and Cartilage Regeneration

This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the

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Genetic Engineering of Mesenchymal Stem Cells

Genetic Engineering of Mesenchymal Stem Cells
  • Author : Jan A. Nolta
  • Publisher : Springer Science & Business Media
  • Release : 29 August 2006
GET THIS BOOKGenetic Engineering of Mesenchymal Stem Cells

MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor revascularization, and thus may be used as delivery vehicles to target ablative agents into dividing tumor cells. Recently the characteristics of human MSC from adipose (fat) tissue have also been identified. The possibility of

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Mesenchymal Stem Cells

Mesenchymal Stem Cells
  • Author : Phuc Van Pham
  • Publisher : BoD – Books on Demand
  • Release : 29 November 2017
GET THIS BOOKMesenchymal Stem Cells

Mesenchymal Stem Cells: Isolation, Characterization, and Applications thoroughly presents the isolation, characterization, and some applications of mesenchymal stem cells in the clinic. The book has two parts: "Isolation and Characterization" and "Clinical Perspectives and Applications." In Part I, the subsequent chapters introduce some techniques in isolation, characterization, and purification of mesenchymal stem cells in different tissues. In Part II, some applications of mesenchymal stem cells in the popular diseases, which include cartilage regeneration, spinal cord injury, and osteoarthritis, are discussed.

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The Growth Plate

The Growth Plate
  • Author : Irving M. Shapiro,Barbara Boyan,H. Clarke Anderson
  • Publisher : IOS Press
  • Release : 27 October 2021
GET THIS BOOKThe Growth Plate

Evidence generated by a number of genetic studies indicates that growth is regulated by a number of genes and that interference with their expression can have catastrophic effects on the well being of the whole organism. This work covers skeletal development and growth.

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Principles of Regenerative Medicine

Principles of Regenerative Medicine
  • Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
  • Publisher : Academic Press
  • Release : 16 December 2010
GET THIS BOOKPrinciples of Regenerative Medicine

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure.

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A Textbook of Advanced Oral and Maxillofacial Surgery

A Textbook of Advanced Oral and Maxillofacial Surgery
  • Author : Mohammad Hosein Motamedi
  • Publisher : BoD – Books on Demand
  • Release : 31 August 2016
GET THIS BOOKA Textbook of Advanced Oral and Maxillofacial Surgery

Advanced oral and maxillofacial surgery encompasses a vast array of diseases, disorders, defects, and deformities as well as injuries of the mouth, head, face, and jaws. It relates not only to treatment of impacted teeth, facial pain, misaligned jaws, facial trauma, oral cancers, jaw cysts, and tumors but also to facial cosmetic surgery and placement of dental and facial implants. This specialty is evolving alongside advancements in technology and instrumentation. Volume 1 has topped 132,000 chapter downloads so far, and Volume 2 is

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Resident Stem Cells and Regenerative Therapy

Resident Stem Cells and Regenerative Therapy
  • Author : Regina Coeli dos Santos Goldenberg,Antonio Carlos Campos de Carvalho
  • Publisher : Academic Press
  • Release : 27 October 2021
GET THIS BOOKResident Stem Cells and Regenerative Therapy

In the last 3 decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the

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