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Methods of Therapeutic Drug Monitoring Including Pharmacogenetics

Methods of Therapeutic Drug Monitoring Including Pharmacogenetics
  • Author : Georg Hempel
  • Publsiher : Elsevier
  • Release : 17 October 2019
  • ISBN : 0444640673
  • Pages : 380 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKMethods of Therapeutic Drug Monitoring Including Pharmacogenetics

Summary:
Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot technology and microextraction methods. In addition, the book includes new drugs, such as tyrosine kinase inhibitors and the monitoring of immunosuppressant drugs. Presents a unique, interdisciplinary approach that appeals to a wide range of users Written by authors from international labs, providing a global perspective that can be applied in various regulatory environments Features additional therapeutic drugs to reflect the rising number of immunocompromised patients Includes a new mass spectroscopic methods chapter to capture the frequent use in TDM and the improved availability of LC-MS across laboratories


Methods of Therapeutic Drug Monitoring Including Pharmacogenetics

Methods of Therapeutic Drug Monitoring Including Pharmacogenetics
  • Author : Georg Hempel
  • Publisher : Elsevier
  • Release : 17 October 2019
GET THIS BOOKMethods of Therapeutic Drug Monitoring Including Pharmacogenetics

Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot

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Handbook of Drug Monitoring Methods

Handbook of Drug Monitoring Methods
  • Author : Amitava Dasgupta
  • Publisher : Springer Science & Business Media
  • Release : 23 October 2007
GET THIS BOOKHandbook of Drug Monitoring Methods

In Handbook of Drug Monitoring Methods: Therapeutics and Drug Abuse, authors discuss the different analytical techniques used in today’s practice of therapeutic drug monitoring and drugs of abuse as well as alcohol testing with relevant theory, mechanism, and in-depth scientific discussion on each topic. This volume is the perfect handbook and quick reference for any clinical laboratory, allowing clinicians to find the potential source of a false-positive or a false-negative result in the daily operation of a toxicology laboratory.

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Therapeutic Drug Monitoring Data

Therapeutic Drug Monitoring Data
  • Author : Amitava Dasgupta,Matthew Krasowski
  • Publisher : Academic Press
  • Release : 14 September 2019
GET THIS BOOKTherapeutic Drug Monitoring Data

Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs

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Therapeutic Drug Monitoring

Therapeutic Drug Monitoring
  • Author : Amitava Dasgupta
  • Publisher : Academic Press
  • Release : 07 June 2012
GET THIS BOOKTherapeutic Drug Monitoring

Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathologists, toxicologists, clinical chemists,

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Drug Monitoring and Clinical Chemistry

Drug Monitoring and Clinical Chemistry
  • Author : Georg Hempel
  • Publisher : Elsevier
  • Release : 15 May 2004
GET THIS BOOKDrug Monitoring and Clinical Chemistry

Drug Monitoring and Clinical Chemistry, the 5th volume in the Handbook of Analytical Separations series, gives an overview about methods to analyse drugs in biological fluids. The most widely used methods to analyse drugs in biological fluids. i.e. chromatographic methods, CE and immunoassays are described in detail. For important drugs, an overview about the methods available and a comparison of the techniques should be given to enable the reader to choose the right method depending on laboratory equipment, staff,

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Personalized Immunosuppression in Transplantation

Personalized Immunosuppression in Transplantation
  • Author : Michael Oellerich,Amitava Dasgupta
  • Publisher : Elsevier
  • Release : 08 August 2015
GET THIS BOOKPersonalized Immunosuppression in Transplantation

Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring. The book is written for pathologists, toxicologists, and transplant surgeons who are involved in the management of transplant patients, offering them in-depth coverage of the management of immunosuppressant therapy in transplant patients with the goal of maximum benefit from drug therapy

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Clinical Challenges in Therapeutic Drug Monitoring

Clinical Challenges in Therapeutic Drug Monitoring
  • Author : William Clarke,Amitava Dasgupta
  • Publisher : Elsevier
  • Release : 21 July 2016
GET THIS BOOKClinical Challenges in Therapeutic Drug Monitoring

Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process

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Individualized Drug Therapy for Patients

Individualized Drug Therapy for Patients
  • Author : Roger W Jelliffe,Michael Neely
  • Publisher : Academic Press
  • Release : 15 November 2016
GET THIS BOOKIndividualized Drug Therapy for Patients

Individualized Drug Therapy for Patients: Basic Foundations, Relevant Software and Clinical Applications focuses on quantitative approaches that maximize the precision with which dosage regimens of potentially toxic drugs can hit a desired therapeutic goal. This book highlights the best methods that enable individualized drug therapy and provides specific examples on how to incorporate these approaches using software that has been developed for this purpose. The book discusses where individualized therapy is currently and offers insights to the future. Edited by

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Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine

Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine
  • Author : David F. Kisor,Professor of Pharmacokinetics Chair Department of Pharmaceutical and Biomedical Sciences Ohio Northern University Raabe College of Pharmacy David F Kisor,Michael D. Kane,Jon E. Sprague,Jeffery N. Talbot
  • Publisher : Jones & Bartlett Publishers
  • Release : 01 February 2013
GET THIS BOOKPharmacogenetics, Kinetics, and Dynamics for Personalized Medicine

Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine provides a primer to understand pharmacogenetics (the study of genetic factors that influence how a drug works) in the applied context of pharmacokinetics (how the body handles a drug) and pharmacodynamics (the effects of a drug on the body). This valuable foundation illuminates how these principles and scientific advances can create optimal individual patient care, that is, personalized medicine. Through specific drug examples, this resource explores how the genetic constitution of an individual

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Topics on Drug Metabolism

Topics on Drug Metabolism
  • Author : James Paxton
  • Publisher : BoD – Books on Demand
  • Release : 22 February 2012
GET THIS BOOKTopics on Drug Metabolism

In order to avoid late-stage drug failure due to factors such as undesirable metabolic instability, toxic metabolites, drug-drug interactions, and polymorphic metabolism, an enormous amount of effort has been expended by both the pharmaceutical industry and academia towards developing more powerful techniques and screening assays to identify the metabolic profiles and enzymes involved in drug metabolism. This book presents some in-depth reviews of selected topics in drug metabolism. Among the key topics covered are: the interplay between drug transport and

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Drug Metabolizing Enzymes

Drug Metabolizing Enzymes
  • Author : Jae Lee,R. Scott Obach,Michael B. Fisher
  • Publisher : CRC Press
  • Release : 03 September 2003
GET THIS BOOKDrug Metabolizing Enzymes

Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P450 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P450 and similar enzymes - as well as parallel issues shaping the pharmaceutical industry - to promote the next generation of safer, more effective drugs.

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Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book
  • Author : Nader Rifai
  • Publisher : Elsevier Health Sciences
  • Release : 16 January 2017
GET THIS BOOKTietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book

The Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 6th Edition provides the most current and authoritative guidance on selecting, performing, and evaluating the results of new and established laboratory tests. This classic clinical chemistry reference offers encyclopedic coverage detailing everything you need to know, including: analytical criteria for the medical usefulness of laboratory tests, variables that affect tests and results, laboratory medicine, applications of statistical methods, and most importantly clinical utility and interpretation of laboratory tests. It is THE

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Synthesis of Essential Drugs

Synthesis of Essential Drugs
  • Author : Ruben Vardanyan,Victor Hruby
  • Publisher : Elsevier
  • Release : 10 March 2006
GET THIS BOOKSynthesis of Essential Drugs

Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active

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