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Models of Protection Against HIV SIV

Models of Protection Against HIV SIV
  • Author : Gianfranco Pancino
  • Publsiher : Academic Press
  • Release : 02 November 2011
  • ISBN : 0123877164
  • Pages : 360 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKModels of Protection Against HIV SIV

Summary:
A successful vaccine for the prevention and/or immunotherapy against HIV/AIDS is one of the prominent challenges of the 21st century. To date, all human vaccine trials against this virus/disease have resulted in failure, or at best have shown very low efficacy. The scientific community dealing with HIV/AIDS has unanimously proposed a focus on basic science, with the intention of identifying correlates of protection that can serve as guides in developing and evaluating vaccine preparation. However, Nature seems to have already found several ways of dealing with infections by HIV and related primate lentiviruses, either by resisting infection or, once infected, avoiding immune damage and immunodeficiency. Models of Protection Against HIV/SIV will allow for an in-depth reflection on the perspectives for vaccine and therapy research derived from important recent studies. It will be authored by some of the most well known specialists in the field of HIV resistance/protection: including F. Barré-Sinoussi (2008 Nobel Prize for Medicine winner), B. Walker, S. Rowland-Jones, A. Telenti, M. Lederman and F. Plummer. This book is structured in a unique way, looking at three models of resistance/protection separately and then comparing the models against one another to provide its readership with a detailed examination of the research that is most predominant in the search for a vaccine. This structure presents the information in an easy-to-understand format and gives the book a cross-discipline appeal -- an important reference for those in the scientific community, medical care, public health and academia alike. Provides extensive descriptions and comparisons on the different models of protection agains HIV/AIDS Comprehensive writing and illustrations Contributors are among the most eminent specialists in the field


Models of Protection Against HIV/SIV

Models of Protection Against HIV/SIV
  • Author : Gianfranco Pancino,Guido Silvestri,Keith Fowke
  • Publisher : Academic Press
  • Release : 02 November 2011
GET THIS BOOKModels of Protection Against HIV/SIV

A successful vaccine for the prevention and/or immunotherapy against HIV/AIDS is one of the prominent challenges of the 21st century. To date, all human vaccine trials against this virus/disease have resulted in failure, or at best have shown very low efficacy. The scientific community dealing with HIV/AIDS has unanimously proposed a focus on basic science, with the intention of identifying correlates of protection that can serve as guides in developing and evaluating vaccine preparation. However, Nature

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Models of Protection Against HIV/SIV

Models of Protection Against HIV/SIV
  • Author : Gianfranco Pancino,Guido Silvestri,Keith R. Fowke
  • Publisher : Academic Press
  • Release : 01 January 2012
GET THIS BOOKModels of Protection Against HIV/SIV

A successful vaccine for the prevention and/or immunotherapy against HIV/AIDS is one of the prominent challenges of the 21st century. To date, all human vaccine trials against this virus/disease have resulted in failure, or at best have shown very low efficacy. The scientific community dealing with HIV/AIDS has unanimously proposed a focus on basic science, with the intention of identifying correlates of protection that can serve as guides in developing and evaluating vaccine preparation. However, Nature

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Health of HIV Infected People

Health of HIV Infected People
  • Author : Ronald Ross Watson
  • Publisher : Academic Press
  • Release : 29 April 2015
GET THIS BOOKHealth of HIV Infected People

Health of HIV Infected People: Food, Nutrition and Lifestyle Without Antiretroviral Drugs defines the supportive roles of bioactive foods, exercise, and dietary supplements on the health of HIV infected people who do not have access to resources or those who choose not to utilize antiretroviral drugs. Approaches such as the application of traditional herbs and foods are given careful definition by experts who define the risks and benefits of such practices within this important context. Readers learn how to treat

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AIDS Research at EC Level

AIDS Research at EC Level
  • Author : Andre E. Baert
  • Publisher : IOS Press
  • Release : 22 May 1995
GET THIS BOOKAIDS Research at EC Level

At EC level the fight against AIDS, one of the major health problems and socioeconomic diseases today, is also part of the specific RTD programme in the field of biomedicine and health. About 600 research teams are collaborating within 30 concerted actions networks that are underpinned by centralised facilities. For example, the epidemiology research networks are monitored by the WHO/EC collaborating centre in St. Maurice, France. Common experiments on animal models, antiviral screening, genetic analysis of multiple virus strains and provision

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Natural Hosts of SIV

Natural Hosts of SIV
  • Author : Aftab A. Ansari,Guido Silvestri
  • Publisher : Newnes
  • Release : 04 July 2014
GET THIS BOOKNatural Hosts of SIV

Natural Hosts of SIV: Implications in AIDS thoroughly reviews the possible mechanisms by which African nonhuman primate natural hosts of lentiviruses remain essentially disease-free while other hosts exhibit disease and death. The book ultimately indicates directions for further research and potential translations of this compelling phenomenon into novel approaches to treat and prevent HIV. When Asian non-human primate non-natural hosts are experimentally infected with viruses isolated from African species, disease and death normally results. Meanwhile, these African nonhuman primate natural

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Human Immunodeficiency Virus type 1 (HIV-1) and Breastfeeding

Human Immunodeficiency Virus type 1 (HIV-1) and Breastfeeding
  • Author : Athena P. Kourtis,Marc Bulterys
  • Publisher : Springer Science & Business Media
  • Release : 28 March 2012
GET THIS BOOKHuman Immunodeficiency Virus type 1 (HIV-1) and Breastfeeding

The HIV pandemic continues to levy a heavy burden on the human race world-wide. The estimated number of people who became newly infected with HIV in 2009 was 2.6 million; most of these individuals live in Sub-Saharan Africa, followed by India and Southeast Asia. An estimated 370,000 new cases of pediatric infections occurred globally in 2009 (or more than 1,000 new infections every day), practically all of them through mother-to-child transmission. Up to 40% of all new infant HIV infections occur during breastfeeding. While breastfeeding by

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Lymph Node T Cell Dynamics and Novel Strategies for HIV Cure

Lymph Node T Cell Dynamics and Novel Strategies for HIV Cure
  • Author : Constantinos Petrovas,Vijayakumar Velu
  • Publisher : Frontiers Media SA
  • Release : 11 February 2019
GET THIS BOOKLymph Node T Cell Dynamics and Novel Strategies for HIV Cure

Currently, more than 36 million people are infected with HIV. Although the introduction of highly active anti-retroviral therapy (HAART) has led to substantial advances in the clinical management of HIV infected individuals, HAART cannot completely eliminate the virus. This is because CD4 T helper cells, harboring the virus, remain dormant reservoirs. These reservoirs are difficult to measure and are present even in HAART-treated HIV infected individuals with undetectable levels of HIV in the blood. A growing body of studies has revealed

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Chimpanzees in Biomedical and Behavioral Research

Chimpanzees in Biomedical and Behavioral Research
  • Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research
  • Publisher : National Academies Press
  • Release : 05 January 2012
GET THIS BOOKChimpanzees in Biomedical and Behavioral Research

For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model

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Mysteries of Type I IFN response: benefits versus detriments

Mysteries of Type I IFN response: benefits versus detriments
  • Author : Arno Müllbacher,Yoichi Furuya,Herbert Patrick Ludewick
  • Publisher : Frontiers Media SA
  • Release : 29 July 2015
GET THIS BOOKMysteries of Type I IFN response: benefits versus detriments

Successful containment of an infection is dependent on both innate and adaptive immune response. Cytokines are essential effectors of both of these systems. In particular, type I interferons (IFN-I) are important components of early innate immunity against an infection. However, the production of IFN-I could serve as a double edge sword, either containing an infection or enhancing susceptibility. For example, IFN-I, which is essential for early containment of viral infections, has been shown to be detrimental to the host during

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