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Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
  • Author : Asla Pitkänen,Paul Buckmaster, DVM, PhD,Aristea S Galanopoulou,Solomon L. Moshé
  • Publisher : Academic Press
  • Release : 14 June 2017
GET THIS BOOKModels of Seizures and Epilepsy

Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of

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Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
  • Author : Asla Pitkänen,Philip A. Schwartzkroin,Solomon L. Moshé
  • Publisher : Elsevier
  • Release : 04 October 2005
GET THIS BOOKModels of Seizures and Epilepsy

An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30 years, an overview of the most widely-used models of seizures and epilepsy. Chapters cover a broad range of experimental approaches (from in vitro to whole animal preparations), a variety of epileptiform

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Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
  • Author : Asla Pitkänen,Solomon L. Mosh,Aristea S. Galanopoulou
  • Publisher : Academic Press
  • Release : 16 June 2017
GET THIS BOOKModels of Seizures and Epilepsy

Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of

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Encyclopedia of Basic Epilepsy Research

Encyclopedia of Basic Epilepsy Research
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 27 May 2009
GET THIS BOOKEncyclopedia of Basic Epilepsy Research

As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent

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Animal Models of Epilepsy

Animal Models of Epilepsy
  • Author : Scott C. Baraban
  • Publisher : Anonim
  • Release : 01 January 2009
GET THIS BOOKAnimal Models of Epilepsy

Animal models provide a means to investigate fundamental mechanisms of abnormal electrical discharge i.e., seizures. Taking advantage of transgenic and homologous recombination techniques, laboratories have recently moved beyond the standard convulsant or stimulation models in rat to develop novel mouse models of epilepsy. This book provides a review of the current and emerging animal models used to study epilepsy. Prior textbooks devoted to models of seizure and epilepsy almost exclusively categorized rat models with little attention paid to these

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Jasper's Basic Mechanisms of the Epilepsies

Jasper's Basic Mechanisms of the Epilepsies
  • Author : Jeffrey Noebels,Massimo Avoli,Michael Rogawski,Richard Olsen,Antonio Delgado-Escueta
  • Publisher : Oxford University Press
  • Release : 01 June 2012
GET THIS BOOKJasper's Basic Mechanisms of the Epilepsies

H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these

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Epileptic Seizures and the EEG

Epileptic Seizures and the EEG
  • Author : Andrea Varsavsky,Iven Mareels,Mark Cook
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOKEpileptic Seizures and the EEG

A study of epilepsy from an engineering perspective, this volume begins by summarizing the physiology and the fundamental ideas behind the measurement, analysis and modeling of the epileptic brain. It introduces the EEG and provides an explanation of the type of brain activity likely to register in EEG measurements, offering an overview of how these EEG records are and have been analyzed in the past. The book focuses on the problem of seizure detection and surveys the physiologically based dynamic

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Experimental Models of Epilepsy and Related Comorbidities

Experimental Models of Epilepsy and Related Comorbidities
  • Author : Mohd. Farooq Shaikh,Ayanabha Chakraborti,Annamaria Vezzani,Jafri Malin Abdullah
  • Publisher : Frontiers Media SA
  • Release : 19 June 2019
GET THIS BOOKExperimental Models of Epilepsy and Related Comorbidities

Epileptic patients live with epilepsy-associated complications such as cognitive dysfunction, psychological discomfort, and sexual function decline, and are more likely to experience emotional and mental health issues problems, including depression and anxiety. Many antiepileptic drugs are found to have a role in aggravating psychiatric symptoms. Animal models, which inform translational questions about epilepsy comorbidities, are used to study the relationship between epilepsy and related comorbidities. The aim of this Research Topic was to highlight basic, clinical and interdisciplinary research involved

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The Causes of Epilepsy

The Causes of Epilepsy
  • Author : Simon D. Shorvon,Frederick Andermann,Renzo Guerrini
  • Publisher : Cambridge University Press
  • Release : 14 April 2011
GET THIS BOOKThe Causes of Epilepsy

Causation is an aspect of epilepsy neglected in the scientific literature and in the conceptualization of epilepsy at a clinical and experimental level. It was to remedy this deficiency that this book was conceived. The book opens with a draft etiological classification that goes some way to filling the nosological void. The book is divided into four etiological categories: idiopathic, symptomatic, cryptogenic, and provoked epilepsies. Each chapter considers topics in a consistent fashion, dealing with the phenomenon of epilepsy in

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Drugs for the Control of Epilepsy

Drugs for the Control of Epilepsy
  • Author : Carl L. Faingold,Gerhard H. Fromm
  • Publisher : CRC Press
  • Release : 04 June 2019
GET THIS BOOKDrugs for the Control of Epilepsy

Originally published in 1991. This book brings together the ideas of an international group of experts on clinical and experimental epilepsy. These authors consider how antiepileptic drugs may act on elements of neuronal networks to reduce seizure incidence and severity. The book addresses such topics as the four general classes of anticonvulsant drug mechanisms, major epilepsy models, the proposed mechanisms of action of major antiepileptic drugs, and the clinical use of antiepileptic drugs in the treatment of various forms of human

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Recent Advances in Predicting and Preventing Epileptic Seizures

Recent Advances in Predicting and Preventing Epileptic Seizures
  • Author : Ronald Tetzlaff,Christian E Elger,Klaus Lehnertz
  • Publisher : World Scientific
  • Release : 28 August 2013
GET THIS BOOKRecent Advances in Predicting and Preventing Epileptic Seizures

This book is to improve our understanding of mechanisms leading to seizures in humans and in developing new therapeutic options. The book covers topics such as recent approaches to seizure control, recent developments in signal processing of interest for seizure prediction, ictogenesis in complex epileptic brain networks, active probing of the pre-seizure state, non-EEG based approaches to the transition to seizures, microseizures and their role in the generation of clinical seizures, the impact of sleep and long-biological cycles on seizure

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Seizures and Epilepsy

Seizures and Epilepsy
  • Author : Jerome Engel
  • Publisher : Oxford University Press
  • Release : 31 January 2013
GET THIS BOOKSeizures and Epilepsy

This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.

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Genetics of Epilepsy

Genetics of Epilepsy
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 04 September 2014
GET THIS BOOKGenetics of Epilepsy

The book chapters cover different aspects of epilepsy genetics, starting with the "classical" concept of epilepsies as ion channel disorders. The second part of the book gives credit to the fact that by now non-ion channel genes are recognized as equally important causes of epilepsy. The concluding chapters are designed to offer the reader insight into current methods in epilepsy research. Each chapter is self-contained and deals with a selected topic of interest. Authors are the leading experts in the

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Neuropharmacology Methods in Epilepsy Research

Neuropharmacology Methods in Epilepsy Research
  • Author : Steven L. Peterson,Timothy E. Albertson
  • Publisher : CRC Press
  • Release : 07 May 2019
GET THIS BOOKNeuropharmacology Methods in Epilepsy Research

There is an estimated 2.5 million epileptics in the US and perhaps some 40 million worldwide. As research has become increasingly molecular in scope, fewer scientists are trained in the US on basic, integrated epilepsy techniques. One frustration in neuroscience today is the application of state-of-the-art molecular biology techniques to inappropriate animal models of epilepsy - frequently resulting in inconclusive results. Epilepsy research will be increasingly undertaken by scientists well-trained in reductionist methodology, but who may be unfamiliar with integrated, whole-animal techniques.

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