• Home
  • Molecular and Cellular Therapies for Motor Neuron Diseases

Molecular and Cellular Therapies for Motor Neuron Diseases

Molecular and Cellular Therapies for Motor Neuron Diseases
  • Author : Nicholas M Boulis
  • Publsiher : Academic Press
  • Release : 18 January 2017
  • ISBN : 0128025247
  • Pages : 336 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKMolecular and Cellular Therapies for Motor Neuron Diseases

Summary:
Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials. Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy


Molecular and Cellular Therapies for Motor Neuron Diseases

Molecular and Cellular Therapies for Motor Neuron Diseases
  • Author : Nicholas M Boulis,Deirdre O’Connor,Anthony Donsante
  • Publisher : Academic Press
  • Release : 18 January 2017
GET THIS BOOKMolecular and Cellular Therapies for Motor Neuron Diseases

Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms.

Book Molecular and Cellular Therapies for Motor Neuron Diseases PDF Download/ Read Online


Motor Neuron Disease in Adults

Motor Neuron Disease in Adults
  • Author : Mark Bromberg
  • Publisher : Oxford University Press
  • Release : 02 October 2014
GET THIS BOOKMotor Neuron Disease in Adults

Motor Neuron Disease in Adults reviews new information as it applies to all aspects of motor neuron disease (ALS, PLS, PMA). The choice of articles is for those that use evidence-based methods to ensure that the new information is solid and advances the topic or issue. The book can be used by anyone who provides any type of care to ALS patients. In particular, neurologists will find the latest information on diagnosis and management, as well as new information on

Book Motor Neuron Disease in Adults PDF Download/ Read Online


Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis

Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis
  • Author : Ricardo Tapia
  • Publisher : Frontiers Media SA
  • Release : 11 February 2015
GET THIS BOOKCellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS), which was described since 1869 by Jean Martin Charcot, is a devastating neurodegenerative disease characterized by the selective and progressive loss of upper and lower motor neurons of the cerebral cortex, brainstem and the spinal cord. The cognitive process is not affected and is not merely the result of aging because may occur at young ages. The only known cause of the disease is associated with genetic mutations, mainly in the gene encoding superoxide dismutase 1 (familial ALS),

Book Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis PDF Download/ Read Online


Novel Aspects on Motor Neuron Disease

Novel Aspects on Motor Neuron Disease
  • Author : Humberto Foyaca Sibat,Lourdes de Fátima Ibañez-Valdés
  • Publisher : BoD – Books on Demand
  • Release : 20 May 2020
GET THIS BOOKNovel Aspects on Motor Neuron Disease

Dedicated to our readers, we include novel information (not reported in IntechOpen’s books before) about new contributions of aberrant astrocytes to MND damage and death in the SOD1G93A rat experimental model of ALS; novel genetic studies on ALS; an update of the structural and functional consequences of the spinal muscular atrophy-linked mutations of the survival motor neuron protein; stem cell therapy for MND; and the novel treatment for SMA and ALS in the introductory chapter. This book

Book Novel Aspects on Motor Neuron Disease PDF Download/ Read Online


Motor Neuron Disease

Motor Neuron Disease
  • Author : Kevin Talbot,Rachael Marsden,Rachel Botell
  • Publisher : Oxford University Press
  • Release : 26 October 2021
GET THIS BOOKMotor Neuron Disease

Written and designed to provide comprehensive, easily accessible advice for all healthcare professionals involved in the care of patients with this challenging condition, this book addresses the entire care pathway from presentation to diagnosis to symptom management and end of life issues.

Book Motor Neuron Disease PDF Download/ Read Online


The Molecular and Cellular Basis of Neurodegenerative Diseases

The Molecular and Cellular Basis of Neurodegenerative Diseases
  • Author : Michael S. Wolfe
  • Publisher : Academic Press
  • Release : 29 March 2018
GET THIS BOOKThe Molecular and Cellular Basis of Neurodegenerative Diseases

The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative

Book The Molecular and Cellular Basis of Neurodegenerative Diseases PDF Download/ Read Online


Spinal Muscular Atrophy

Spinal Muscular Atrophy
  • Author : Charlotte J Sumner,Sergey Paushkin,Chien-Ping Ko
  • Publisher : Academic Press
  • Release : 24 October 2016
GET THIS BOOKSpinal Muscular Atrophy

Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of

Book Spinal Muscular Atrophy PDF Download/ Read Online


Current Advances in Amyotrophic Lateral Sclerosis

Current Advances in Amyotrophic Lateral Sclerosis
  • Author : Alvaro Estévez
  • Publisher : BoD – Books on Demand
  • Release : 11 September 2013
GET THIS BOOKCurrent Advances in Amyotrophic Lateral Sclerosis

Our understanding of the pathology of amyotrophic lateral sclerosis is a continuously changing field. New hypotheses are generated with each new discovery; they are abandoned to be reanalyzed after some time under the light of new observations. This book present a series of reviews from experts in different aspects of the disease focus on these hypotheses. There are also a few review chapters providing clear examples of these new observations that make the field to reanalyze previous conclusions.

Book Current Advances in Amyotrophic Lateral Sclerosis PDF Download/ Read Online


CELL BIOLOGY AND TRANSLATIONAL MEDICINE

CELL BIOLOGY AND TRANSLATIONAL MEDICINE
  • Author : Anonim
  • Publisher : Springer Nature
  • Release : 26 October 2021
GET THIS BOOKCELL BIOLOGY AND TRANSLATIONAL MEDICINE

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as

Book CELL BIOLOGY AND TRANSLATIONAL MEDICINE PDF Download/ Read Online



Autophagy in Health and Disease

Autophagy in Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 30 June 2020
GET THIS BOOKAutophagy in Health and Disease

Autophagy in Health and Disease, Volume 175, presents the latest insights from renowned experts in the field who discuss the key role of autophagic responses in the preservation of cellular and organismal homeostasis and how defects in the molecular apparatus for autophagy drive or accompany disease. Specific chapters in this new release include Crosstalk between autophagy and cell death signaling: mechanisms and therapeutic relevance, C. elegans to model autophagy-related human disorders, Autophagy in Kidney Disease: advances and therapeutic potential, Autophagy in

Book Autophagy in Health and Disease PDF Download/ Read Online


Patterning and Cell Type Specification in the Developing CNS and PNS

Patterning and Cell Type Specification in the Developing CNS and PNS
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 06 May 2013
GET THIS BOOKPatterning and Cell Type Specification in the Developing CNS and PNS

The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all

Book Patterning and Cell Type Specification in the Developing CNS and PNS PDF Download/ Read Online


The Neuron

The Neuron
  • Author : Irwin B. Levitan,Leonard K. Kaczmarek
  • Publisher : Oxford University Press, USA
  • Release : 26 October 2021
GET THIS BOOKThe Neuron

Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.

Book The Neuron PDF Download/ Read Online


Liver Regeneration and Carcinogenesis

Liver Regeneration and Carcinogenesis
  • Author : Gerard Meurant
  • Publisher : Elsevier
  • Release : 27 September 1995
GET THIS BOOKLiver Regeneration and Carcinogenesis

Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines.

Book Liver Regeneration and Carcinogenesis PDF Download/ Read Online


Molecular Mechanisms of Neural Development and Insights into Disease

Molecular Mechanisms of Neural Development and Insights into Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 09 March 2021
GET THIS BOOKMolecular Mechanisms of Neural Development and Insights into Disease

Neural Development and Disease, Volume 142 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters by one or more members of an international board of authors. Sections in this new release cover The role of primary cilia in neural development and disease, Mechanisms of axon guidance receptor regulation and signaling, Synaptic recognition molecules in development and disease, The regulation of cortical neurogenesis, Axon guidance in the developing spinal cord,

Book Molecular Mechanisms of Neural Development and Insights into Disease PDF Download/ Read Online