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Monoclonal Antibodies

Monoclonal Antibodies
  • Author : James W. Goding
  • Publsiher : Anonim
  • Release : 27 October 1986
  • ISBN : 0987654321
  • Pages : 315 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKMonoclonal Antibodies

Summary:
This book represents the distillation and critical evaluation of many hundreds of publications relating to the production and use of antibodies. Therefore it is restricted to the "core" techniques of production and handling of antibodies, and their use in studies of antigen analysis, purification and localization.



Monoclonal Antibodies

Monoclonal Antibodies
  • Author : Steven Shire
  • Publisher : Woodhead Publishing
  • Release : 24 April 2015
GET THIS BOOKMonoclonal Antibodies

Monoclonal antibodies (MAbs) are currently the major class of protein bio therapeutic being developed by biotechnology and pharmaceutical companies. Monoclonal Antibodies discusses the challenges and issues revolving around development of a monoclonal antibody produced by recombinant DNA technology into a therapeutic agent.This book covers downstream processing which includes design of processes to manufacture the formulation, formulation design, fill and finish into closure systems and routes of administration. The characterization of the final drug product is covered where the use

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Monoclonal Antibody and Immunosensor Technology

Monoclonal Antibody and Immunosensor Technology
  • Author : A.M. Campbell
  • Publisher : Elsevier
  • Release : 12 December 1991
GET THIS BOOKMonoclonal Antibody and Immunosensor Technology

This highly practical book, and successor to Volume 13 in the Laboratory Techniques series, explores further and provides more comprehensive, autoritative information on the production of Mabs. Much new and illuminating material has been included covering the concepts behind the application of recombinant DNA technology and biosensor technology to monoclonal antibodies, and all the human Mab technology facilitated by PCR of antibody genes. Also included in this latest volume is a section focussing on other methods of obtaining B cell clones

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Monoclonal Antibody Production

Monoclonal Antibody Production
  • Author : National Research Council,Institute for Laboratory Animal Research,Committee on Methods of Producing Monoclonal Antibodies
  • Publisher : National Academies Press
  • Release : 06 June 1999
GET THIS BOOKMonoclonal Antibody Production

The American Anti-Vivisection Society (AAVS) petitioned the National Institutes of Health (NIH) on April 23, 1997, to prohibit the use of animals in the production of mAb. On September 18, 1997, NIH declined to prohibit the use of mice in mAb production, stating that "the ascites method of mAb production is scientifically appropriate for some research projects and cannot be replaced." On March 26, 1998, AAVS submitted a second petition, stating that "NIH failed to provide valid scientific reasons for not supporting a proposed ban." The

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Therapeutic Monoclonal Antibodies

Therapeutic Monoclonal Antibodies
  • Author : Zhiqiang An
  • Publisher : John Wiley & Sons
  • Release : 20 September 2011
GET THIS BOOKTherapeutic Monoclonal Antibodies

70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies. First book to address the discovery and development of antibody therapeutics in their entirety. Most chapters contain experimental data to illustrate the principles described in them. Authors provide detailed methodologies that readers can take away with them and use in their own laboratories.

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Monoclonal Antibodies in Headache

Monoclonal Antibodies in Headache
  • Author : Antoinette Maassen van den Brink,Paolo Martelletti
  • Publisher : Springer
  • Release : 07 May 2021
GET THIS BOOKMonoclonal Antibodies in Headache

Intended to promote a more appropriate and modern therapeutic approach to migraine management, this book is the first to deal with monoclonal antibodies in this context. Authored by the most respected migraine experts from around the globe and drawing on the lessons learned in both clinical trials and clinical practice, it reviews the current state of knowledge on this important therapeutic innovation, which has produced impressive data in randomized controlled trials, and the efficacy and safety of which have been

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Monoclonal Antibodies

Monoclonal Antibodies
  • Author : Vincent Ossipow,Nicolas Fischer
  • Publisher : Humana Press
  • Release : 23 August 2016
GET THIS BOOKMonoclonal Antibodies

Monoclonal Antibodies: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed modern approaches to isolate and characterize monoclonal antibodies against carefully selected epitopes. This edition includes new chapters covering the key steps to generate high quality monoclonals via different methods, from antigen generation to epitope mapping and quality control of the purified IgG. Chapters are divided into four parts corresponding to four distinct objectives. Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody

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Trends in Monoclonal Antibody Research

Trends in Monoclonal Antibody Research
  • Author : Marie A. Simmons
  • Publisher : Nova Publishers
  • Release : 27 October 2021
GET THIS BOOKTrends in Monoclonal Antibody Research

This new and important international source of information brings together leading-edge research dedicated to monoclonal antibodies. Monoclonal antibodies (MABs) are: antibodies of exceptional purity and specificity; components of the immune system; able to recognise and bind to a specific antigen. Monoclonal antibodies are currently utilised in many diagnostic procedures, including: measuring protein and drug levels in serum; typing tissue and blood; identifying infectious agents; identifying clusters of differentiation for the classification and follow-up therapy of leukaemias and lymphomas; identifying tumour

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Monoclonal Antibodies

Monoclonal Antibodies
  • Author : Roger H. Kennett
  • Publisher : Springer
  • Release : 30 March 2012
GET THIS BOOKMonoclonal Antibodies

On August 7, 1975, Kohler and Milstein published in Nature (256:495) a report describing "Continuous cultures of fused cells secreting antibody of predefined specificity. " Their report has become a classic and has already had a profound effect on basic and applied research in biology and medicine. By the time the first Workshop on Lymphocyte Hybridomas (Current Topics in Microbiology and Im munology 81, 1978) was held on April 3-5, 1978, in Bethesda, Maryland, investi gators from many laboratories had made hybrids between plasmacytomas and spleen cells

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The Lock and Key of Medicine

The Lock and Key of Medicine
  • Author : Lara Marks
  • Publisher : Yale University Press
  • Release : 01 January 2015
GET THIS BOOKThe Lock and Key of Medicine

This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies, or Mabs. Though unfamiliar to most nonscientists, these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. They have radically changed understandings of the pathways of disease, enabling faster, cheaper, and more accurate clinical diagnostic testing. And they lie at the heart of the development of genetically engineered drugs such as interferon and blockbuster personalized therapies such as Herceptin. Lara V. Marks recounts

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A Practical Guide to Monoclonal Antibodies

A Practical Guide to Monoclonal Antibodies
  • Author : J. Eryl Liddell,A. Cryer
  • Publisher : John Wiley & Sons
  • Release : 26 August 1991
GET THIS BOOKA Practical Guide to Monoclonal Antibodies

Includes all of the information required to produce monoclonal antibodies in the laboratory and to prepare them for use in a multitude of given applications. Production procedures are treated in chronological order, beginning with basic tissue culture techniques, immunization strategies and screening test design, followed by production of hybridoma cell lines and basic antibody characterization, purification and labeling. Each chapter contains explanatory text on each step with comparative analysis of methods where appropriate. All necessary experimental protocols are presented in

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Monoclonal Antibodies

Monoclonal Antibodies
  • Author : Nima Rezaei
  • Publisher : BoD – Books on Demand
  • Release : 23 June 2021
GET THIS BOOKMonoclonal Antibodies

Immune-based therapies are being studied extensively in a variety of immunological conditions due to their high precision and sensitivity. Monoclonal antibody (mAb) technology is a major advancement in the treatment of several infectious diseases, malignancies, and immunological disorders. This book provides comprehensive information about technologies, characterization, and application of mAbs in the clinic and laboratory.

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Monoclonal Antibodies

Monoclonal Antibodies
  • Author : Philip Shepherd,Christopher J. Dean
  • Publisher : Practical Approach (Paperback)
  • Release : 27 October 2021
GET THIS BOOKMonoclonal Antibodies

Monoclonal Antibodies: A Practical Approach covers the preparation, testing, derivation, and applications of monoclonal antibodies. New immunological techniques incorporating tried and tested methodologies are described, making the book of interest to established and inexperienced immunologists. Both the standard somatic hybridization technique and recombinant techniques, including the use of phage libraries, for the preparation of rodent and human monoclonal antibodies are described. Protocols for both the small and large scale production are detailed, as well as purification and labelling (with both

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Monoclonal Antibodies and Functional Cell Lines

Monoclonal Antibodies and Functional Cell Lines
  • Author : Roger H. Kennett
  • Publisher : Springer Science & Business Media
  • Release : 08 March 2013
GET THIS BOOKMonoclonal Antibodies and Functional Cell Lines

This volume serves as a follow-up to our previous book, MonoclonalAntibodies Hybridomas: A New Dimension in Biological Analyses. We continue the theme of monoclonal antibodies and their applications, attempting to cover some of the areas not covered in the previous volume. We again include an appendix de scribing methods useful to those who ar-e beginning to apply these techniques in their own laboratories. This volume will be followed by another concentrating on the combination of monoclonal antibody techniques with molecular

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