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Morphological Mouse Phenotyping

Morphological Mouse Phenotyping
  • Author : Jesús Ruberte París
  • Publisher : Anonim
  • Release : 17 October 2021
GET THIS BOOKMorphological Mouse Phenotyping

Disease animal models are fundamental in research to improve human health. The success of using genetically engineered mice to evaluate molecular disease hypothesis has encouraged the development of massive European and global projects making the mouse the most used animal disease model. Laboratory mouse populations are straining the housing capacity of pharmaceutical and biotechnology companies, as well as public research institutions. However, the scientific community lacks sufficient expertise in morphological phenotyping to effectively characterize and validate these animal models. The

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High-throughput Transgenic Mouse Phenotyping Using Microscopic-MRI.

High-throughput Transgenic Mouse Phenotyping Using Microscopic-MRI.
  • Author : J. O. S. Cleary
  • Publisher : Anonim
  • Release : 17 October 2021
GET THIS BOOKHigh-throughput Transgenic Mouse Phenotyping Using Microscopic-MRI.

With the completion of the human genome sequence in 2003, efforts have shifted towards elucidating gene function. Such phenotypic investigations are aided by advances in techniques for genetic modification of mice, with whom we share ~99% of genes. Mice are key models for both examination of basic gene function and translational study of human conditions. Furthering these efforts, ambitious programmes are underway to produce knockout mice for the ~25,000 mouse genes. In the coming years, methods to rapidly phenotype mouse morphology will be

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Comparative Anatomy and Histology

Comparative Anatomy and Histology
  • Author : Piper M. Treuting,Suzanne M. Dintzis
  • Publisher : Academic Press
  • Release : 01 January 2012
GET THIS BOOKComparative Anatomy and Histology

Comparative Anatomy and Histology: A Mouse and Human Atlas is aimed at the new mouse investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse anatomy and histology using direct comparison to the human. The side by side comparison of mouse and human tissues highlight the unique biology of the mouse, which has great impact on the validation of mouse models of human

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Pathology of the Developing Mouse

Pathology of the Developing Mouse
  • Author : Brad Bolon
  • Publisher : CRC Press
  • Release : 24 April 2015
GET THIS BOOKPathology of the Developing Mouse

Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology experimentation in mice but, more importantly, a "how to interpret" resource for pathologists and other biomedical scientists faced for the first or hundredth time with defining

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Mouse Retinal Phenotyping

Mouse Retinal Phenotyping
  • Author : Naoyuki Tanimoto
  • Publisher : Humana Press
  • Release : 22 March 2018
GET THIS BOOKMouse Retinal Phenotyping

The aim of this volume is to provide a wide range of techniques and aspects of mouse retinal phenotyping and characterization. Chapters guide readers through morphological and functional properties of the mouse retina and techniques for the analysis of outer to mid-retina and mid- to inner retina. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on

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Neuroanatomy of the Mouse

Neuroanatomy of the Mouse
  • Author : Hannsjörg Schröder,Natasha Moser,Stefan Huggenberger
  • Publisher : Springer Nature
  • Release : 28 February 2020
GET THIS BOOKNeuroanatomy of the Mouse

This textbook describes the basic neuroanatomy of the laboratory mouse. The reader will be guided through the anatomy of the mouse nervous system with the help of abundant microphotographs and schemata. Learning objectives and summaries of key facts at the beginning of each chapter provide the reader with an overview on the most important information. As transgenic mice are one of the most widely used paradigms when it comes to modeling human diseases, a basic understanding of the neuroanatomy of

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Kaufman’s Atlas of Mouse Development Supplement

Kaufman’s Atlas of Mouse Development Supplement
  • Author : Richard Baldock,Jonathan Bard,Duncan Davidson,Gillian Morriss-Kay
  • Publisher : Academic Press
  • Release : 23 September 2015
GET THIS BOOKKaufman’s Atlas of Mouse Development Supplement

Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas

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Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine

Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine
  • Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use
  • Publisher : National Academies Press
  • Release : 29 May 2018
GET THIS BOOKAdvancing Disease Modeling in Animal-Based Research in Support of Precision Medicine

Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed

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Pathology of Genetically Engineered and Other Mutant Mice

Pathology of Genetically Engineered and Other Mutant Mice
  • Author : John P. Sundberg,Peter Vogel,Jerrold M. Ward
  • Publisher : John Wiley & Sons
  • Release : 29 December 2021
GET THIS BOOKPathology of Genetically Engineered and Other Mutant Mice

PATHOLOGY OF GENETICALLY ENGINEERED AND OTHER MUTANT MICE An updated and comprehensive reference to pathology in every organ system in genetically modified mice The newly revised and thoroughly updated Second Edition of Pathology of Genetically Engineered and Other Mutant Mice delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, and includes descriptions and explanations of a wide range of findings, as well

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Bioprinting

Bioprinting
  • Author : Kenneth Douglas
  • Publisher : Oxford University Press
  • Release : 17 October 2021
GET THIS BOOKBioprinting

"Bioprinting: To Make Ourselves Anew describes how bioprinting emerged from 3D printing and details the accomplishments and challenges in bioprinting tissues of cartilage, skin, bone, muscle, neuromuscular junctions, liver, heart, lung, and kidney. It explains how scientists are attempting to provide these bioprinted tissues with a blood supply and the ability to carry nerve signals so that the tissues might be used for transplantation into persons with diseased or damaged organs. The book presents all the common terms in the

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Essentials of Laboratory Animal Science: Principles and Practices

Essentials of Laboratory Animal Science: Principles and Practices
  • Author : P. Nagarajan,Ramachandra Gudde,Ramesh Srinivasan
  • Publisher : Springer Nature
  • Release : 24 August 2021
GET THIS BOOKEssentials of Laboratory Animal Science: Principles and Practices

This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing

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The Guide to Investigation of Mouse Pregnancy

The Guide to Investigation of Mouse Pregnancy
  • Author : B. Anne Croy,Aureo T. Yamada,Francesco J. DeMayo,S. Lee Adamson
  • Publisher : Academic Press
  • Release : 09 December 2013
GET THIS BOOKThe Guide to Investigation of Mouse Pregnancy

The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of

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Mouse Genetics

Mouse Genetics
  • Author : Shree Ram Singh,Robert M. Hoffman,Amit Singh
  • Publisher : Humana
  • Release : 20 February 2021
GET THIS BOOKMouse Genetics

This fully updated edition provides selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplish the manipulation of genes of interest, tracing cell lineages, and modeling human diseases. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding

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