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Nervous System Drug Delivery

Nervous System Drug Delivery
  • Author : Russell R. Lonser
  • Publsiher : Academic Press
  • Release : 25 June 2019
  • ISBN : 0128139986
  • Pages : 556 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKNervous System Drug Delivery

Summary:
Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and trainees will find this a critical resource for understanding and applying nervous system drug delivery techniques. Offers an up-to-date, comprehensive resource on drug delivery to the nervous system Provides a bridge for understanding across nervous system delivery-related physiology, drug delivery principles. and the methodologies that underlie the various methods of drug distribution (with clinical application) Written for a broad audience of researchers, clinicians and advanced graduate students in neuroscience, neurology, neurosurgery, pharmacology, radiology and psychiatry


Nervous System Drug Delivery

Nervous System Drug Delivery
  • Author : Russell R. Lonser,Malisa Sarntinoranont,Kristof Bankiewicz
  • Publisher : Academic Press
  • Release : 25 June 2019
GET THIS BOOKNervous System Drug Delivery

Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and


Nervous System Drug Delivery

Nervous System Drug Delivery
  • Author : Russell R. Lonser,Malisa Sarntinoranont,Kristof Bankiewicz
  • Publisher : Academic Press
  • Release : 25 June 2019
GET THIS BOOKNervous System Drug Delivery

Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and


Drug Delivery to the Brain

Drug Delivery to the Brain
  • Author : Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lange,Robert G. Thorne
  • Publisher : Springer Science & Business Media
  • Release : 03 December 2013
GET THIS BOOKDrug Delivery to the Brain

The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics


Drug Delivery

Drug Delivery
  • Author : Binghe Wang,Longqin Hu,Teruna J. Siahaan
  • Publisher : John Wiley & Sons
  • Release : 09 March 2016
GET THIS BOOKDrug Delivery

Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal


Brain Targeted Drug Delivery Systems

Brain Targeted Drug Delivery Systems
  • Author : Huile Gao,Xiaoling Gao
  • Publisher : Academic Press
  • Release : 20 September 2018
GET THIS BOOKBrain Targeted Drug Delivery Systems

Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat


Blood-Brain Barrier in Drug Discovery

Blood-Brain Barrier in Drug Discovery
  • Author : Li Di,Edward H. Kerns
  • Publisher : John Wiley & Sons
  • Release : 02 February 2015
GET THIS BOOKBlood-Brain Barrier in Drug Discovery

Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery. • Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects • Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies • Covers BBB physiology, medicinal chemistry design


Nanomedicines for Brain Drug Delivery

Nanomedicines for Brain Drug Delivery
  • Author : Javier O. Morales,Pieter J. Gaillard
  • Publisher : Humana
  • Release : 20 November 2020
GET THIS BOOKNanomedicines for Brain Drug Delivery

This volume explores the latest research in central nervous system (CNS) targeted nanocarriers, methods for their synthesis, and its characterization process. Chapters in this book cover topics such as polymeric nanoparticles and liposomes; self-assembled peptide-based scaffolds for lesions of the nervous system; use of peptides as CNS drugs and as potential carriers to optimize brain-targeted delivery; ways to model and assess blood brain barrier absorption of drugs; and the role of neurodegeneration progress of nanomaterials and their potential toxicity concerns.


Liposomes

Liposomes
  • Author : Angel Catala
  • Publisher : BoD – Books on Demand
  • Release : 25 October 2017
GET THIS BOOKLiposomes

Liposomes have received increased attention in recent years. Nevertheless, liposomes, due to their various forms and applications, require further investigation. These structures can deliver both hydrophilic and hydrophobic drugs. Preparation of liposomes results in different properties for these systems. In addition, there are many factors and difficulties that affect the development of liposome drug delivery structure. The purpose of this book is to concentrate on recent developments on liposomes. The articles collected in this book are contributions by invited researchers


Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors
  • Author : Prashant Kesharwani,Umesh Gupta
  • Publisher : Academic Press
  • Release : 20 April 2018
GET THIS BOOKNanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. Addresses the


The Blood-brain Barrier and Drug Delivery to the Cns

The Blood-brain Barrier and Drug Delivery to the Cns
  • Author : Michael Bradbury,Jorg Kreuter,David Begley
  • Publisher : CRC Press
  • Release : 30 August 2019
GET THIS BOOKThe Blood-brain Barrier and Drug Delivery to the Cns

This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on the physiological mechanisms that influence the passage of agents into the brain, the book covers the latest research on the blood-brain barrier, the current problems of and solutions to drug delivery to the central nervous system (CNS), existing strategies, and prospects for future research. Avoid excessive in vivo experimentation and utilize timesaving in vitro techniques. A concise reference with reviews from


The Effects of Drug Abuse on the Human Nervous System

The Effects of Drug Abuse on the Human Nervous System
  • Author : Bertha Madras,Michael Kuhar
  • Publisher : Elsevier
  • Release : 15 November 2013
GET THIS BOOKThe Effects of Drug Abuse on the Human Nervous System

Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences,


Drug Delivery to the Central Nervous System

Drug Delivery to the Central Nervous System
  • Author : Kewal K. Jain
  • Publisher : Humana Press
  • Release : 21 December 2009
GET THIS BOOKDrug Delivery to the Central Nervous System

Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In


Nanoparticulate Drug Delivery Systems

Nanoparticulate Drug Delivery Systems
  • Author : Deepak Thassu,Michel Deleers,Yashwant Vishnupant Pathak
  • Publisher : CRC Press
  • Release : 30 March 2007
GET THIS BOOKNanoparticulate Drug Delivery Systems

With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e


The Blood Brain Barrier (BBB)

The Blood Brain Barrier (BBB)
  • Author : Gert Fricker,Melanie Ott,Anne Mahringer
  • Publisher : Springer
  • Release : 24 October 2014
GET THIS BOOKThe Blood Brain Barrier (BBB)

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series


Enhancement in Drug Delivery

Enhancement in Drug Delivery
  • Author : Elka Touitou,Brian W. Barry
  • Publisher : CRC Press
  • Release : 27 November 2006
GET THIS BOOKEnhancement in Drug Delivery

Providing a significant cross-fertilization of ideas across several disciplines, Enhancement in Drug Delivery offers a unique comprehensive review of both theoretical and practical aspects of enhancement agents and techniques used for problematic administration routes. It presents an integrated evaluation of absorption enhancers and modes fo