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Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma
  • Author : Michael G. Fehlings
  • Publsiher : Academic Press
  • Release : 15 December 2020
  • ISBN : 9780128198353
  • Pages : 400 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKNeural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

Summary:
Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout. These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma. Contains contributions by international authors Covers recent clinical trial advancements and findings and updates on ongoing trials Presents an overview of clinical practice guidelines for the management of traumatic spinal cord injury featured Provides the reader with insights regarding the translation of research from bench to bedside and the skills needed to understand the translational pathway using real-life examples


Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma
  • Author : Michael G. Fehlings,Brian Kwon,Alexander R. Vaccaro,F. Cumhur Oner
  • Publisher : Academic Press
  • Release : 15 December 2020
GET THIS BOOKNeural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included

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Spinal Cord Injury (SCI) Repair Strategies

Spinal Cord Injury (SCI) Repair Strategies
  • Author : Giuseppe Perale,Filippo Rossi
  • Publisher : Woodhead Publishing
  • Release : 30 October 2019
GET THIS BOOKSpinal Cord Injury (SCI) Repair Strategies

Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential

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Indwelling Neural Implants

Indwelling Neural Implants
  • Author : William M. Reichert
  • Publisher : CRC Press
  • Release : 17 December 2007
GET THIS BOOKIndwelling Neural Implants

Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment examines many of these challenges, paying particular attention to how the healing of tissues surrounding an implant can impact the intended use of a device. The contributions are divided

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AOSpine Masters Series, Volume 7: Spinal Cord Injury and Regeneration

AOSpine Masters Series, Volume 7: Spinal Cord Injury and Regeneration
  • Author : Luiz Roberto Gomes Vialle,Michael G. Fehlings,Norbert Weidner
  • Publisher : Thieme
  • Release : 30 October 2016
GET THIS BOOKAOSpine Masters Series, Volume 7: Spinal Cord Injury and Regeneration

World-renowned experts share the latest updates in translational research as well as surgical and nonsurgical strategies for treating spinal cord injury Spinal cord injury (SCI) is a devastating, clinically challenging injury, leading to varying degrees of neurological function impairment and paralysis. Underlying biological mechanisms either inhibit or promote new growth in the spinal cord. Researchers have been making important discoveries about how neurons and their axons grow in the central nervous system and why they fail to regenerate after SCI.

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Spinal Cord Injury

Spinal Cord Injury
  • Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,Committee on Spinal Cord Injury
  • Publisher : National Academies Press
  • Release : 27 July 2005
GET THIS BOOKSpinal Cord Injury

An estimated 11,000 spinal cord injuries occur each year in the United States and more than 200,000 Americans suffer from maladies associated with spinal cord injury. This includes paralysis, bowel and bladder dysfunction, sexual dysfunction, respiratory impairment, temperature regulation problems, and chronic pain. During the last two decades, longstanding beliefs about the inability of the adult central nervous system to heal itself have been eroded by the flood of new information from research in the neurosciences and related fields. However, there are

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Trends in Cell Signaling Pathways in Neuronal Fate Decision

Trends in Cell Signaling Pathways in Neuronal Fate Decision
  • Author : Sabine Wislet
  • Publisher : BoD – Books on Demand
  • Release : 27 March 2013
GET THIS BOOKTrends in Cell Signaling Pathways in Neuronal Fate Decision

During the last decades, numerous studies about stem cells and regenerative medicine highlighted new therapeutic approaches to treat several neurological disorders. It is noteworthy that the current optimism over potential stem cell therapies is driven by new understandings of stem cell biology leading to specific cell fate decision. The objectives of this book were: 1) to offer a general understanding of signaling pathways underlying the capacity of differentiation of several types of stem cells into neurons, during the development; 2) to understand

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Neuroproteomics

Neuroproteomics
  • Author : Oscar Alzate
  • Publisher : CRC Press
  • Release : 26 October 2009
GET THIS BOOKNeuroproteomics

In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we begin to unravel the complex mysteries of neurological diseases that less than a generation ago seemed opaque to our inquiries, if not altogether intractable. Edited

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Spinal Cord Injury

Spinal Cord Injury
  • Author : Joost Verhaagen,John W. McDonald III
  • Publisher : Newnes
  • Release : 31 December 2012
GET THIS BOOKSpinal Cord Injury

Handbook of Clinical Neurology: Spinal Cord Injury summarizes advances in the clinical diagnosis, monitoring, prognostication, treatment, and management of spinal cord injuries. More specifically, it looks at new and important developments in areas such as high-resolution noninvasive neuroimaging, surgery, and electrical stimulation of motor, respiratory, bladder, bowel, and sexual functions. It also reviews the latest insights into spontaneous regeneration and recovery of function following rehabilitation, with emphasis on novel therapeutic strategies, such as gene therapy, transcranial stimulation, brain-machine interfaces, pharmacological

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Essentials of Spinal Cord Injury Medicine

Essentials of Spinal Cord Injury Medicine
  • Author : Yannis Dionyssiotis
  • Publisher : BoD – Books on Demand
  • Release : 13 June 2018
GET THIS BOOKEssentials of Spinal Cord Injury Medicine

Spinal cord injury is a severe condition leading to serious neurological dysfunctions and changes a person's life in a sudden way. Understanding the pathophysiology of spinal cord injury will improve the prognosis and reintegration to the society of spinal cord-injured subjects. The book Essentials in Spinal Cord Injury Medicine includes seven chapters with valuable information addressing hot topics related to spinal cord injury, ranging from pathophysiology, nontraumatic spinal cord injury, complications to exoskeletons, and research therapies with mesenchymal stem cells.

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Neuroprotection and Regeneration of the Spinal Cord

Neuroprotection and Regeneration of the Spinal Cord
  • Author : Kenzo Uchida,Masaya Nakamura,Hiroshi Ozawa,Shinsuke Katoh,Yoshiaki Toyama
  • Publisher : Springer
  • Release : 08 July 2014
GET THIS BOOKNeuroprotection and Regeneration of the Spinal Cord

Neuroprotection and Regeneration of the Spinal Cord comprehensively covers the most recent research in the field of spinal cord injury. The first part of this book focuses on the latest animal models and clinically oriented work, providing extensive information on morphological factors and, biomechanical analysis, in addition to the mechanism of functional recovery. The book goes on to provide information on clinical relevance introducing analysis of spinal cord injuries using MRI and PET. Edited by renowned experts in the field,

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Topics in Paraplegia

Topics in Paraplegia
  • Author : Yannis Dionyssiotis
  • Publisher : BoD – Books on Demand
  • Release : 02 July 2014
GET THIS BOOKTopics in Paraplegia

Spinal cord injury related paraplegia changes a person's life in a sudden way. The most important issue for physicians, therapists and caregivers is to manage the complications that arise, and help paraplegic subjects return to a productive integrated life within society. The book Topics in Paraplegia provides modern knowledge in this direction. Addressing hot topics related to paraplegia, ranging from surgical management to research therapies with mesenchymal stem cells, this book could be a valued reference for physiatrists, neurosurgeons, orthopaedic

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Recovery of Motor Function Following Spinal Cord Injury

Recovery of Motor Function Following Spinal Cord Injury
  • Author : Heidi Fuller,Monte Gates
  • Publisher : BoD – Books on Demand
  • Release : 17 August 2016
GET THIS BOOKRecovery of Motor Function Following Spinal Cord Injury

Restoration of motor function following spinal cord injury is a complex and challenging task. By reviewing emerging cellular, pharmacological, rehabilitative, as well as surgical approaches, this book seeks to highlight promising therapeutic strategies for the repair and regeneration of motor circuitry. The multidisciplinary nature of these approaches illustrates various routes to bridging the gap between the bench and the bedside and to identify the challenges that must be overcome in order to bring about a viable therapeutic strategy for spinal

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Spinal Cord Injury Therapy

Spinal Cord Injury Therapy
  • Author : José Juan Antonio Ibarra Arias,Gabriel Guízar-Sahagún,Elisa García-Vences
  • Publisher : BoD – Books on Demand
  • Release : 27 November 2019
GET THIS BOOKSpinal Cord Injury Therapy

Spinal cord injury (SCI) is one of the main pathologies causing significant loss of neurological function. Therefore, a variety of pharmacological and non-pharmacological therapies are the aims of several studies. To provide the best care, it is important to know and understand the therapeutic approaches that have shown important progress in this topic. This book contains eight chapters that are divided into three sections: Introduction, Pharmacological Therapies, and Non-Pharmacological Therapies. The authors of the chapters deal with the pathophysiology of

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Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
  • Author : Lucas G. Chase,Mohan C Vemuri
  • Publisher : Springer Science & Business Media
  • Release : 12 December 2012
GET THIS BOOKMesenchymal Stem Cell Therapy

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host

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