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New Combination Approaches to Enhance Rituximab Based Lymphoma Therapies

New Combination Approaches to Enhance Rituximab Based Lymphoma Therapies
  • Author : Anonim
  • Publsiher : Academic Press
  • Release : 01 November 2020
  • ISBN : 0128167378
  • Pages : 250 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKNew Combination Approaches to Enhance Rituximab Based Lymphoma Therapies

Summary:
New Combination Approaches to Enhance Rituximab-Based Lymphoma Therapies provides general updated information on the resistance of various human lymphoma/leukemia subtypes to anti-CD20 therapeutic antibodies. It discusses also the description of various targeted sensitizing agents that can reverse innate or acquired resistance when used in combination with various FDA-approved anti-CD20 antibodies. There have been a lot of reports in which the treatment with anti-CD20 antibodies for various lymphomas/leukemias has resulted in significant clinical responses; however, there have been also subsets of cancer patients who did not respond initially and several of the responding patients developed resistance to subsequent treatments with the same or different regimens. Therefore, the use of various immunosensitizing agents targeting resistant factors to reverse resistance has been considered and this book discusses each of them in depth, such as Bortexomib, Immunomodulation Agents, Obinutuzumab, Tumor Suppressors, and HDAC Inhibitors. This book is a valuable source for cancer researchers, oncologists, pharmacologists and different members of biomedical field interested in fighting cancer resistance to anti-CD20 antibodies. Provides a general overview of various sensitizing agents that can work effectively when used in combination with anti-CD20 antibodies to reverse resistance Offers potential underlying mechanisms by which the cancer cells are either inherently resistant or become unresponsive to further antibody treatments Discusses how to develop new targeted agents to underlie resistance in order to expand research on this field


New Combination Approaches to Enhance Rituximab-Based Lymphoma Therapies

New Combination Approaches to Enhance Rituximab-Based Lymphoma Therapies
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 01 November 2020
GET THIS BOOKNew Combination Approaches to Enhance Rituximab-Based Lymphoma Therapies

New Combination Approaches to Enhance Rituximab-Based Lymphoma Therapies provides general updated information on the resistance of various human lymphoma/leukemia subtypes to anti-CD20 therapeutic antibodies. It discusses also the description of various targeted sensitizing agents that can reverse innate or acquired resistance when used in combination with various FDA-approved anti-CD20 antibodies. There have been a lot of reports in which the treatment with anti-CD20 antibodies for various lymphomas/leukemias has resulted in significant clinical responses; however, there have been also

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High Dose Chemotherapy

High Dose Chemotherapy
  • Author : Paul C. Lorigan,Elisabeth Vandenberghe
  • Publisher : CRC Press
  • Release : 11 April 2002
GET THIS BOOKHigh Dose Chemotherapy

This text presents an overview of the basic science and principles of high dose chemotherapy, current state-of-the-art techniques and future developments such as gene therapy. The main section of the book is disease-based, setting the scientific principles within a clinical context and reviewing the application of high dose therapy in specific diseases. Additional sections discuss supportive care and long-term complications. High Dose Chemotherapy is directed at hematologists, clinical and medical oncologists in training or with an interest, rather than direct

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Resistance to Ibritumomab in Lymphoma

Resistance to Ibritumomab in Lymphoma
  • Author : Makoto Hosono,Jean-François Chatal
  • Publisher : Springer
  • Release : 24 April 2018
GET THIS BOOKResistance to Ibritumomab in Lymphoma

This volume, in discussing resistance to ibritumomab, will focus on the mechanism, hematological aspects, radiological and nuclear medicine aspects, and medical physics that deal with radiation dosimetry, and will outline future prospects for overcoming resistance and enhancing efficacy of ibritumomab.

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Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy

Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy
  • Author : Benjamin Bonavida
  • Publisher : Springer Science & Business Media
  • Release : 31 July 2008
GET THIS BOOKSensitization of Cancer Cells for Chemo/Immuno/Radio-therapy

This book reviews novel approaches developed to reverse tumor cell resistance to chemo/immuno/radio-therapy and the use of various sensitizing agents in combination with various cytotoxics. It also introduces several current approaches developed by established investigators that are aimed at overcoming resistance. This is the first volume to compile studies on tumor cell sensitization. It will prove useful for students, scientists, clinicians and pharmaceutical companies.

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Targeted Therapies in Cancer

Targeted Therapies in Cancer
  • Author : Manfred Dietel
  • Publisher : Springer Science & Business Media
  • Release : 10 June 2007
GET THIS BOOKTargeted Therapies in Cancer

From its introduction, oncological chemotherapy has been encumbered by poor selectivity because antiproliferative drugs are often toxic not only to tumor cells but also to important populations of the body’s non-neoplastic cells. Modern targeted therapies interact with defined molecules present on cancer cells, adding increased selectivity to their toxic effects. This book presents an integrated critical view on the theories, mechanisms, problems and pitfalls of the targeted therapy approach.

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Perry's The Chemotherapy Source Book

Perry's The Chemotherapy Source Book
  • Author : Michael C. Perry,Donald C. Doll,Carl E. Freter
  • Publisher : Lippincott Williams & Wilkins
  • Release : 30 July 2012
GET THIS BOOKPerry's The Chemotherapy Source Book

Perry’s The Chemotherapy Source Book, now in its fifth edition, provides information on the choice of chemotherapeutic agents, the use of combination chemotherapy, and the toxicity of individual drugs. Organized by site, this is the only book of its kind to focus strictly on the clinical practice of chemotherapy, and is meant to serve as a “one-stop shop” for information on choice of chemotherapeutic agents, treatment outlines, grading of side effects, and dose modification.

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Immunogenic Cell Death in Cancer: From Benchside Research to Bedside Reality

Immunogenic Cell Death in Cancer: From Benchside Research to Bedside Reality
  • Author : Abhishek D Garg,Patrizia Agostinis
  • Publisher : Frontiers Media SA
  • Release : 29 April 2016
GET THIS BOOKImmunogenic Cell Death in Cancer: From Benchside Research to Bedside Reality

Classically, anti-cancer therapies have always been applied with the primary aim of tumor debulking achieved through widespread induction of cancer cell death. While the role of host immune system is frequently considered as host protective in various (antigen-bearing) pathologies or infections yet in case of cancer overtime it was proposed that the host immune system either plays no role in therapeutic efficacy or plays a limited role that is therapeutically unemployable. The concept that the immune system is dispensable for

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Cancer Immunology

Cancer Immunology
  • Author : Nima Rezaei
  • Publisher : Springer
  • Release : 29 December 2014
GET THIS BOOKCancer Immunology

This translational book describes in detail the clinical application of novel approaches in cancer immunotherapy with the aim of educating clinicians in the implications of the most recent research and new developments in the field. The scope is broad, encompassing, for example, prognostic biomarkers for personalized cancer treatment, strategies for targeting tumor immunosuppression, gene therapy, virus-based vaccines, targeting of cancer stem cells, hematopoietic stem cell transplantation, the role of T lymphocytes in cancer immunotherapy, use of monoclonal antibodies, and many

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Management of Hematologic Malignancies

Management of Hematologic Malignancies
  • Author : Susan O'Brien,Julie M. Vose,Hagop M. Kantarjian
  • Publisher : Cambridge University Press
  • Release : 18 November 2010
GET THIS BOOKManagement of Hematologic Malignancies

Hematologic malignancies were the first human cancers to be studied in depth at the molecular level, and recent years have seen important advances in treatment. This comprehensive reference book covers the full range of hematologic malignancies, including all subtypes of leukemias, lymphomas, and plasma cell dyscrasias. Authored by internationally known experts, each chapter emphasizes diagnostic work-up, staging, and therapeutic approaches. Up-to-date hematopathology, treatment, and outcomes data are presented in a way which is directly applicable to patient care. Highly illustrated

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Lymphoma: New Insights for the Healthcare Professional: 2012 Edition

Lymphoma: New Insights for the Healthcare Professional: 2012 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release : 10 December 2012
GET THIS BOOKLymphoma: New Insights for the Healthcare Professional: 2012 Edition

Lymphoma: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Lymphoma. The editors have built Lymphoma: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lymphoma in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lymphoma: New Insights for the Healthcare Professional / 2012 Edition

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Indolent Lymphomas

Indolent Lymphomas
  • Author : Martin Dreyling,Marco Ladetto
  • Publisher : Springer Nature
  • Release : 27 January 2021
GET THIS BOOKIndolent Lymphomas

This book provides a comprehensive overview of current treatment strategies in indolent lymphomas, the clinical management of which continues to pose significant challenges for the general oncologist despite the tremendous progress in diagnosis, evaluation of risk factors, and molecular targeted approaches. Experts in the field from around the world describe the histomorphology in a clinically relevant manner, consider the role of risk factors in detail, and discuss the full spectrum of therapeutic approaches. Special emphasis is placed on the translation

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The Physician Assistant Student’s Guide to the Clinical Year Seven-Volume Set

The Physician Assistant Student’s Guide to the Clinical Year Seven-Volume Set
  • Author : Maureen A. Knechtel, MPAS, PA-C
  • Publisher : Springer Publishing Company
  • Release : 15 October 2019
GET THIS BOOKThe Physician Assistant Student’s Guide to the Clinical Year Seven-Volume Set

“A lifesaver – not just for PA students, but for faculty and administrators trying our best to prepare them. Perfect for students to read and use on rotation.” – James Van Rhee, MS, PA-C, DFAAPA, Program Director, Yale Physician Assistant Online Program Everything you’ll need for your clinical rotations in one handy and affordable set! Hit the ground running as you undertake your required clinical rotations with the quick-access, 7-volume pocket-sized set, The Physician Assistant Student’s Guide to the Clinical

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Conn's Current Therapy 2019

Conn's Current Therapy 2019
  • Author : Rick D. Kellerman,David Rakel
  • Publisher : Elsevier Health Sciences
  • Release : 06 December 2018
GET THIS BOOKConn's Current Therapy 2019

Follows a consistent, easy-to-use format throughout, with diagnosis, therapy, drug protocols, and treatment pearls presented in quick-reference boxes and tables for point-of-care answers to common clinical questions. Features significantly revised chapters on sepsis • bacterial pneumonia • ADHD • endometriosis • atrial fibrillation • congestive heart failure • pericarditis • diabetes mellitus • measles • myasthenia gravis • irritable bowel syndrome • Parkinson’s disease • seizures and epilepsy in adolescents and adults • acute bronchitis and other viral respiratory illnesses • urinary incontinence • neutropenia • venous thromboembolism • fungal diseases of the skin • diseases of

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Cancer Immunotherapy: Mechanisms of Cancer Immunity, Engineering Immune- Based Therapies and Developing Clinical Trials

Clinicians, patients and scientists, alike, have been battling cancer for over several decades; however, patient outcomes have not significantly improved over the years with conventional therapies. In recent years, this has caused researchers to look for a change in the status quo, and, the awareness of the human immune system, which has an intrinsic mechanism to control microbial pathogens and dysfunctional self-tissues, has triggered scientists to look for new modes of cancer therapy. Cancer Immunotherapy has become a major research

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Developing Costimulatory Molecules for Immunotherapy of Diseases

Developing Costimulatory Molecules for Immunotherapy of Diseases
  • Author : Manzoor Ahmad Mir
  • Publisher : Academic Press
  • Release : 25 May 2015
GET THIS BOOKDeveloping Costimulatory Molecules for Immunotherapy of Diseases

Developing Costimulatory Molecules for Immunotherapy of Diseases highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy using either humanized antibodies against CD80, CD86, and other costimulatory molecules or CD28 fusinogenic proteins in the treatment of diseases, including allergies, asthma, rheumatoid arthritis, multiple sclerosis, lupus nephritis, severe psoriasis, vulgaris tuberculosis, thopoid, transplantation therapeutic, cancer, and inflammation. The text aims to provide the latest information on the complex roles and interactions within the CD28

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