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Non Canonical Autophagy

Non Canonical Autophagy
  • Author : Lorenzo Galluzzi
  • Publsiher : Academic Press
  • Release : 15 May 2021
  • ISBN : 9780128205389
  • Pages : 250 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKNon Canonical Autophagy

Summary:
Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between 'canonical' and 'non-canonical' forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of 'non-canonical' autophagy. The book discusses all forms of 'non-canonical' autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying 'non-canonical' autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies. Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development


Non-Canonical Autophagy

Non-Canonical Autophagy
  • Author : Lorenzo Galluzzi,Giulia Petroni
  • Publisher : Academic Press
  • Release : 15 May 2021
GET THIS BOOKNon-Canonical Autophagy

Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between 'canonical' and 'non-canonical' forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of 'non-canonical' autophagy. The book discusses all forms of 'non-canonical' autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying 'non-canonical' autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and



Non-canonical Cyclic Nucleotides

Non-canonical Cyclic Nucleotides
  • Author : Roland Seifert
  • Publisher : Springer
  • Release : 28 April 2017
GET THIS BOOKNon-canonical Cyclic Nucleotides

The cyclic purine nucleotides 3’,5’-cAMP and 3’,5’-cGMP are well-established second messengers. cGMP has recently been covered in a volume of the Handbook of Experimental Pharmacology (volume 191). In addition to 3’,5’-cAMP and 3’,5’-cGMP, so-called non-canonical cyclic nucleotides exist. These comprise the cyclic pyrimidine nucleotides 3’,5’-cCMP and 3’,5’-cUMP, the purine nucleotide 3’,5’-cIMP, the 2’,3’-nucleoside monophosphates and cyclic dinucleotides. In this volume of the Handbook of Pharmacology, word-leading experts in the field summarize our current knowledge on these non-canonical cyclic nucleotides, discuss open


Membrane Biogenesis

Membrane Biogenesis
  • Author : Jos A.F. Op den Kamp
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOKMembrane Biogenesis

Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "


Autophagy in Health and Disease

Autophagy in Health and Disease
  • Author : Roberta A. Gottlieb
  • Publisher : Academic Press
  • Release : 16 October 2012
GET THIS BOOKAutophagy in Health and Disease

Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autophagy, allowing the reader quick access to the most applicable information.



Cell Death

Cell Death
  • Author : Tobias Ntuli
  • Publisher : BoD – Books on Demand
  • Release : 16 December 2015
GET THIS BOOKCell Death

This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.


Autophagy

Autophagy
  • Author : Nicholas Ktistakis,Oliver Florey
  • Publisher : Humana Press
  • Release : 05 January 2019
GET THIS BOOKAutophagy

This volume details a comprehensive and extensive set of protocols for the study of autophagy in vitro and in vivo. Chapters focus on mammals, various model organisms, and provide protocols for the study of autophagy-related processes outside of the canonical autophagy pathways. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Prognostic and Therapeutic Applications of Rkip in Cancer

Prognostic and Therapeutic Applications of Rkip in Cancer
  • Author : Benjamin Bonavida,Stavroula Baritaki
  • Publisher : Academic Press
  • Release : 02 March 2020
GET THIS BOOKPrognostic and Therapeutic Applications of Rkip in Cancer

Prognostic and Therapeutic Applications of RKIP in Cancer provides updated reviews on the chemistry, signaling, pre-clinical and clinical activities, and role of RKIP expression levels for diagnostics, prognosis and potential interventions. The development of novel compounds and conjugates that selectively induce RKIP expression in cancer open a novel era of new therapeutics and their potential in the treatment of highly resistant cancers and metastases. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this


Induction of Central Nervous System Disease by the Adaptive Immune Response

Induction of Central Nervous System Disease by the Adaptive Immune Response
  • Author : Robert Weissert,Fabienne Brilot
  • Publisher : Frontiers Media SA
  • Release : 23 November 2017
GET THIS BOOKInduction of Central Nervous System Disease by the Adaptive Immune Response

Over the last years it has become evident that many neurological diseases of the central nervous system (CNS) are induced by a specific adaptive immune response directed against molecules expressed on CNS-resident cells. Well-recognized examples are anti-N-Methyl-D-Aspartate Receptor (NMDAR) encephalitis which is characterized by the presence of antibodies against neuron-expressed NMDAR, or neuromyelitis optica (NMO), induced by antibodies to astrocyte-expressed aquaporin-4. Many more examples exist, and antibodies, and T or/and B cells have increasingly been associated with CNS disease.


Autophagy of the Nervous System

Autophagy of the Nervous System
  • Author : Zhenyu Yue,Charleen T. Chu
  • Publisher : World Scientific
  • Release : 05 March 2021
GET THIS BOOKAutophagy of the Nervous System

What is autophagy? Why would neurons or other brain cells digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as a culprit or accomplice to cell death in others? How does dysfunction of autophagy contribute to neurological diseases and can it be repaired or restored? This book addresses these questions and provide an expert view of the emerging concepts in autophagy research, focusing on autophagic processes and regulation in neurons.


Autophagy Regulation of Innate Immunity

Autophagy Regulation of Innate Immunity
  • Author : Jun Cui
  • Publisher : Springer Nature
  • Release : 14 November 2019
GET THIS BOOKAutophagy Regulation of Innate Immunity

This book discusses novel concepts and discoveries concerning the regulation of innate immunity by autophagy and autophagy-related proteins. In the past decade, there have been major advances in our understanding of the molecular mechanisms of autophagy and its physiological functions. This book highlights emerging studies on the underlying mechanisms of autophagy regulation of innate immunity, including inflammation, antiviral immunity and anti-bacterial responses and the signaling pathways that prompt or inhibit the initiation and progression of related diseases. It also offers



Autophagy: Biology and Diseases

Autophagy: Biology and Diseases
  • Author : Zheng-Hong Qin
  • Publisher : Springer Nature
  • Release : 27 November 2019
GET THIS BOOKAutophagy: Biology and Diseases

This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development