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Nuclear Architecture and Dynamics

Nuclear Architecture and Dynamics
  • Author : Christophe Lavelle
  • Publsiher : Academic Press
  • Release : 27 October 2017
  • ISBN : 012803503X
  • Pages : 618 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKNuclear Architecture and Dynamics

Summary:
Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines. Highlights the link between the (bio)chemistry and the (bio)physics of chromatin Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds


Nuclear Architecture and Dynamics

Nuclear Architecture and Dynamics
  • Author : Christophe Lavelle,Jean-Marc Victor
  • Publisher : Academic Press
  • Release : 27 October 2017
GET THIS BOOKNuclear Architecture and Dynamics

Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists,


Chromatin Regulation and Dynamics

Chromatin Regulation and Dynamics
  • Author : Anita Göndör
  • Publisher : Academic Press
  • Release : 25 October 2016
GET THIS BOOKChromatin Regulation and Dynamics

Chromatin Regulation and Dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The final chapters discuss the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin Regulation and


Nuclear Dynamics

Nuclear Dynamics
  • Author : K. Nagata,K. Takeyasu
  • Publisher : Springer Science & Business Media
  • Release : 03 December 2007
GET THIS BOOKNuclear Dynamics

The dynamics of nuclear structures described in this book furnish the basis for a comprehensive understanding of how the higher-order organization and function of the nucleus is established and how it correlates with the expression of a variety of vital activities such as cell proliferation and differentiation. The resulting volume creates an invaluable source of reference for researchers in the field.



Genomic Imprinting

Genomic Imprinting
  • Author : Rolf Ohlsson
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOKGenomic Imprinting

The form and function of every living organism on the earth depends on the complex regulation of gene expression. This is carried out by controlling and interdigitating spatial and temporal patterns of gene activity during the life time of eukaryotic organisms. This is most dramatically apparent during early stages of development, when new types of cells and organs are being formed, often during very short time spans. To achieve this, it is vital that developmentally important genes can be kept


Visualizing the Dynamics of 4D Nuclear Architecture During Enhancer-Promoter Transcription Activation Using Live Imaging Techniques

The transcription machinery requires spatiotemporal coordination of its regulatory elements for precise gene expression. It is believed that the dynamics in the nuclear architecture like enhancer:promoter looping interaction is essential for the regulation of the transcription machinery. However, the detail of the change in 4D nuclear architecture during transcription is poorly understood. Here we seek to visualize a pair of enhancer and its associated target gene based on a real time, live cell imaging that uses optimized CRISPR-Cas9 and


Nuclear Export of Viral RNAs

Nuclear Export of Viral RNAs
  • Author : J. Hauber,P.K. Vogt
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKNuclear Export of Viral RNAs

In eukaryotic cells, the nuclear genome and its transcriptional apparatus is separated from the site of protein synthesis by the nuclear envelope. Thus, a constant flow of proteins and nucleic acids has to cross the nuclear envelope in both directions. This transport in and out of the nucleus is mediated by nuclear pore complexes (NPCs) and occurs in an energy and signal-dependent manner. Thus, nucleocytoplasmic translocation of macro molecules across the nuclear envelope appears to be a highly specific and


Nuclear Envelope

Nuclear Envelope
  • Author : David Evans,Chris Hutchison,John Bryant
  • Publisher : Taylor & Francis
  • Release : 01 September 2004
GET THIS BOOKNuclear Envelope

The Nuclear Envelope brings together the major current topics in nuclear envelope structure, transport, transcriptional regulation and cell signaling. The volume is divided into four sections: 1. Proteins of the nuclear envelope, including nuclear envelope proteomics, structure and function. 2. Nuclear pores and transport at the nuclear envelope, including pore complex structure, assembly and function and import and export pathways. 3. Nuclear envelope dynamics, including dynamics of lamina assembly and disassembly. 4. Nuclear signaling and transcription regulation, including signaling to the nucleus and spectrin


Spin Dynamics

Spin Dynamics
  • Author : Malcolm H. Levitt
  • Publisher : John Wiley & Sons
  • Release : 20 May 2013
GET THIS BOOKSpin Dynamics

Spin Dynamics: Basics of Nuclear Magnetic Resonance, Second Edition is a comprehensive and modern introduction which focuses on those essential principles and concepts needed for a thorough understanding of the subject, rather than the practical aspects. The quantum theory of nuclear magnets is presented within a strong physical framework, supported by figures. The book assumes only a basic knowledge of complex numbers and matrices, and provides the reader with numerous worked examples and exercises to encourage understanding. With the explicit


Nuclear Strategy in the Modern Era

Nuclear Strategy in the Modern Era
  • Author : Vipin Narang
  • Publisher : Princeton University Press
  • Release : 25 May 2014
GET THIS BOOKNuclear Strategy in the Modern Era

The world is in a second nuclear age in which regional powers play an increasingly prominent role. These states have small nuclear arsenals, often face multiple active conflicts, and sometimes have weak institutions. How do these nuclear states—and potential future ones—manage their nuclear forces and influence international conflict? Examining the reasoning and deterrence consequences of regional power nuclear strategies, this book demonstrates that these strategies matter greatly to international stability and it provides new insights into conflict dynamics


Genome Organization And Function In The Cell Nucleus

Genome Organization And Function In The Cell Nucleus
  • Author : Karsten Rippe
  • Publisher : John Wiley & Sons
  • Release : 09 January 2012
GET THIS BOOKGenome Organization And Function In The Cell Nucleus

By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gained knowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair, recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions and non-coding RNAs, chromatin structure,



Nuclear Command and Control Norms

Nuclear Command and Control Norms
  • Author : Salma Shaheen
  • Publisher : Routledge
  • Release : 28 September 2018
GET THIS BOOKNuclear Command and Control Norms

This book offers a new analytical framework for studying nuclear command and control (C2), based on a comparative study of four nuclear weapons states (NWS). The subject of nuclear operations management has long been shrouded in secrecy, and whilst the importance of nuclear C2 cannot be disputed, there are few academic studies into how and why states develop these systems. This volume includes a comparative study of the development of nuclear C2 by four different NWS (Britain, China, India, and


Critical Dynamics

Critical Dynamics
  • Author : Uwe C. Täuber
  • Publisher : Cambridge University Press
  • Release : 06 March 2014
GET THIS BOOKCritical Dynamics

A comprehensive and unified introduction to describing and understanding complex interacting systems.