• Home
  • Aging Research in Yeast

Aging Research in Yeast

Aging Research in Yeast
  • Author : Michael Breitenbach
  • Publsiher : Springer Science & Business Media
  • Release : 19 November 2011
  • ISBN : 9789400725614
  • Pages : 368 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKAging Research in Yeast

Summary:
This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain). Most mechanisms of aging are studied in yeast. Among them, this book discusses: mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses; the role of autophagy and mitophagy; the relationship of apoptosis to aging processes; the role of asymmetric segregation of damage in replicative aging; the role of replication stress; and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined.


Aging Research in Yeast

Aging Research in Yeast
  • Author : Michael Breitenbach,S. Michal Jazwinski,Peter Laun
  • Publisher : Springer Science & Business Media
  • Release : 19 November 2011
GET THIS BOOKAging Research in Yeast

This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in


Oxidative Stress

Oxidative Stress
  • Author : Helmut Sies
  • Publisher : Elsevier
  • Release : 22 October 2013
GET THIS BOOKOxidative Stress

Oxidative Stress is intended as an in-depth account of knowledge and problems in the field of oxygen-related damage in biological systems. The topics range from an assessment of molecular events in in vitro model systems to complex problems in clinical medicine. Organized into two parts with a total of 18 chapters, this book begins with an introduction to oxidative stress, elucidating specific topics on reactive oxygen species, detoxification system, and nature of oxidative damage. The first part focuses on models used


Brain Aging

Brain Aging
  • Author : David R. Riddle
  • Publisher : CRC Press
  • Release : 19 April 2007
GET THIS BOOKBrain Aging

Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur


Methods in Biological Oxidative Stress

Methods in Biological Oxidative Stress
  • Author : Kenneth Hensley,Robert A. Floyd
  • Publisher : Springer Science & Business Media
  • Release : 05 March 2021
GET THIS BOOKMethods in Biological Oxidative Stress

Methods in Biological Oxidative Stress is practical in scope, and outlines modern techniques for measuring oxidative stress and detecting oxidizing agents both in vitro and in vivo. Free radicals and reactive oxidizing agents, once ignored as meaningful biochemicals entities, are now recognized as causes or contributing factors in dozens if not hundreds of disease states, and free radical metabolism of xenobiotics is increasingly important to pharmacologists. This is the first book to detail experimental methods for detecting free radicals and


Oxidative Stress in Plants

Oxidative Stress in Plants
  • Author : Dirk Inze
  • Publisher : CRC Press
  • Release : 18 October 2001
GET THIS BOOKOxidative Stress in Plants

Plants depend on physiological mechanisms to combat adverse environmental conditions, such as pathogen attack, wounding, drought, cold, freezing, salt, UV, intense light, heavy metals and SO2. Many of these cause excess production of active oxygen species in plant cells. Plants have evolved complex defense systems against such oxidative stress. The



Oxidative Stress and Antioxidant Protection

Oxidative Stress and Antioxidant Protection
  • Author : Donald Armstrong,Robert D. Stratton
  • Publisher : John Wiley & Sons
  • Release : 11 April 2016
GET THIS BOOKOxidative Stress and Antioxidant Protection

Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior


Oxidative Stress, Inflammation, and Health

Oxidative Stress, Inflammation, and Health
  • Author : Young-Joon Surh
  • Publisher : CRC Press
  • Release : 24 May 2005
GET THIS BOOKOxidative Stress, Inflammation, and Health

Specifically focusing on the redox regulation of cell signaling responsible for oxidative stress and inflammatory tissue damage, this reference provides a comprehensive overview of cutting-edge research on the intracellular events mediating or preventing oxidative stress and pro-inflammatory processes induced by endogenous and xenobiotic factors-analyzing the implications of oxidative stress and inflammatory damage in the pathogenesis of human disorders such as cancer, neurodegenerative disease, and diabetes.


Oxidative Stress in Aquatic Ecosystems

Oxidative Stress in Aquatic Ecosystems
  • Author : Doris Abele,Jose Pablo Vazquez-Medina,Tania Zenteno-Savin
  • Publisher : John Wiley & Sons
  • Release : 03 November 2011
GET THIS BOOKOxidative Stress in Aquatic Ecosystems

Reactive oxygen species (ROS) are increasingly appreciated as down-stream effectors of cellular damage and dysfunction under natural and anthropogenic stress scenarios in aquatic systems. This comprehensive volume describes oxidative stress phenomena in different climatic zones and groups of organisms, taking into account specific habitat conditions and how they affect susceptibility to ROS damage. A comprehensive and detailed methods section is included which supplies complete protocols for analyzing ROS production, oxidative damage, and antioxidant systems. Methods are also evaluated with respect


Oxidative Damage to Plants

Oxidative Damage to Plants
  • Author : Parvaiz Ahmad
  • Publisher : Academic Press
  • Release : 29 January 2014
GET THIS BOOKOxidative Damage to Plants

With contributions that review research on this topic throughout the world, Oxidative Damage to Plants covers key areas of discovery, from the generation of reactive oxygen species (ROSs), their mechanisms, quenching of these ROSs through enzymatic and non-enzymatic antioxidants, and detailed aspects of such antioxidants as SOD and CAT. Environmental stress is responsible for the generation of oxidative stress, which causes oxidative damage to biomolecules and hence reduces crop yield. To cope up with these problems, scientists have to fully


Oxidative Stress and Biomaterials

Oxidative Stress and Biomaterials
  • Author : Thomas Dziubla,D Allan Butterfield
  • Publisher : Academic Press
  • Release : 31 May 2016
GET THIS BOOKOxidative Stress and Biomaterials

Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation. No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in


A Master Regulator of Oxidative StressThe Transcription Factor Nrf2

A Master Regulator of Oxidative StressThe Transcription Factor Nrf2
  • Author : Jose Antonio Morales-Gonzalez,Ángel Morales-González,Eduardo Osiris Madrigal-Santillan
  • Publisher : BoD – Books on Demand
  • Release : 21 December 2016
GET THIS BOOKA Master Regulator of Oxidative StressThe Transcription Factor Nrf2

Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in


Oxidative Stress, Exercise and Aging

Oxidative Stress, Exercise and Aging
  • Author : Helaine M. Alessio,Ann E. Hagerman
  • Publisher : World Scientific
  • Release : 05 March 2021
GET THIS BOOKOxidative Stress, Exercise and Aging

Examines oxidative stress in a variety of models, at rest and after exercise. This book presents key concepts of oxidative stress, exercise and aging; explains oxidative stress in different types of exercises; and includes knowledge of the underlying mechanisms influencing health and disease processes associated with oxidative stress.


Oxidative Stress and Chronic Degenerative Diseases

Oxidative Stress and Chronic Degenerative Diseases
  • Author : Jose Antonio Morales-Gonzalez
  • Publisher : BoD – Books on Demand
  • Release : 22 May 2013
GET THIS BOOKOxidative Stress and Chronic Degenerative Diseases

This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican


Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases

Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases
  • Author : Luc Montagnier,Rene Olivier,Catherine Pasquier
  • Publisher : CRC Press
  • Release : 06 October 1997
GET THIS BOOKOxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases

Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity. It covers the chemistry and biochemistry of free radicals, free radicals as second messengers that group the activation of transcription factors and enzymes, the importance of the antioxidant system in cell metabolism regulation, and the role of free radicals and antioxidants in disease