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Polymers and Nanomaterials for Gene Therapy

Polymers and Nanomaterials for Gene Therapy
  • Author : Ravin Narain
  • Publsiher : Woodhead Publishing
  • Release : 09 January 2016
  • ISBN : 0081005210
  • Pages : 302 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKPolymers and Nanomaterials for Gene Therapy

Summary:
Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. Explores current challenges in the research of genetic diseases Discusses polymers for gene therapy and their function in designing advanced materials Provides examples of organic and inorganic nanomaterials for gene therapy Includes labeling, targeting, and assays Looks at characterization, physico-(bio)chemical properties, and applications


Polymers and Nanomaterials for Gene Therapy

Polymers and Nanomaterials for Gene Therapy
  • Author : Ravin Narain
  • Publisher : Woodhead Publishing
  • Release : 09 January 2016
GET THIS BOOKPolymers and Nanomaterials for Gene Therapy

Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials.


Gene Therapy

Gene Therapy
  • Author : Surendra Nimesh
  • Publisher : Woodhead Pub Limited
  • Release : 06 March 2021
GET THIS BOOKGene Therapy

Gene therapy is emerging as a new class of therapeutics for the treatment of inherited and acquired diseases. However, poor cellular uptake and instability of DNA in the physiological milieu limits its therapeutic potential, hence a vector which can protect and efficiently transport DNA to the target cells must be developed. Nanotechnology-based non-viral vectors have been proposed as potential candidates. Various polymeric nanoparticles have been shown to be suitable, with high cellular uptake efficiencies and reduced cytotoxicity. These delivery vectors


Polymeric Gene Delivery

Polymeric Gene Delivery
  • Author : Mansoor M. Amiji
  • Publisher : CRC Press
  • Release : 29 September 2004
GET THIS BOOKPolymeric Gene Delivery

To treat disease or correct genetic disorders using gene therapy, the most suitable vehicle must be able to deliver genes to the appropriate tissues and cells in the body in a specific as well as safe and effective manner. While viruses are the most popular vehicles to date, their disadvantages include toxicity, limited size of genes they can carry, and limited scale of industrial production. Polymeric Gene Delivery: Principles and Applications is the first comprehensive book to specifically address polymeric


Polymeric Nanomaterials in Nanotherapeutics

Polymeric Nanomaterials in Nanotherapeutics
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 26 October 2018
GET THIS BOOKPolymeric Nanomaterials in Nanotherapeutics

Polymeric Nanomaterials in Nanotherapeutics describes how polymeric nanosensors and nanorobotics are used for biomedical instrumentation, surgery, diagnosis and targeted drug delivery for cancer, pharmacokinetics, monitoring of diabetes and healthcare. Key areas of coverage include drug administration and formulations for targeted delivery and release of active agents (drug molecules) to non-healthy tissues and cells. The book demonstrates how these are applied to dental work, wound healing, cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, metabolic diseases, and more. Methods


Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics
  • Author : Prashant Kesharwani,Kishore M. Paknikar,Virendra Gajbhiye
  • Publisher : Academic Press
  • Release : 08 July 2019
GET THIS BOOKPolymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends


Advanced Technology for Delivering Therapeutics

Advanced Technology for Delivering Therapeutics
  • Author : Sabyasachi Maiti,Kalyan Kumar Sen
  • Publisher : BoD – Books on Demand
  • Release : 11 May 2017
GET THIS BOOKAdvanced Technology for Delivering Therapeutics

The goal of any novel drug delivery system is to provide therapeutic benefits to the patients by increasing duration of drug action, reducing dosing frequency, and controlling drug release rate at the target site, thereby reducing unwanted side effects. Advanced Technology for Delivering Therapeutics is a reference book that covers recent developments in the field of drug delivery science and technology. The purpose of this book is to bring together descriptions of some selective technologies including new and promising nanotechnology


Advances in Nanomaterials for Drug Delivery

Advances in Nanomaterials for Drug Delivery
  • Author : Mahdi Karimi,Maryam Rad Mansouri,Navid Rabiee,Michael R Hamblin
  • Publisher : Morgan & Claypool Publishers
  • Release : 05 December 2018
GET THIS BOOKAdvances in Nanomaterials for Drug Delivery

Nanomedicine is a developing field, which includes different disciplines such as material science, chemistry, engineering and medicine devoted to the design, synthesis and construction of high-tech nanostructures. The ability of these structures to have their chemical and physical properties tuned by structural modification, has allowed their use in drug delivery systems, gene therapy delivery, and various types of theranostic approaches. Colloidal noble metal nanoparticles and other nanostructures have many therapeutic and diagnostic applications. The concept of drug targeting as a


Advances in Nanomaterials

Advances in Nanomaterials
  • Author : Mushahid Husain,Zishan Husain Khan
  • Publisher : Springer
  • Release : 15 March 2016
GET THIS BOOKAdvances in Nanomaterials

This book provides a review of the latest research findings and key applications in the field of nanomaterials. The book contains twelve chapters on different aspects of nanomaterials. It begins with key fundamental concepts to aid readers new to the discipline of nanomaterials, and then moves to the different types of nanomaterials studied. The book includes chapters based on the applications of nanomaterials for nano-biotechnology and solar energy. Overall, the book comprises chapters on a variety of topics on nanomaterials


Perspectives in Micro- and Nanotechnology for Biomedical Applications

Perspectives in Micro- and Nanotechnology for Biomedical Applications
  • Author : Juliana M Chan,Chenjie Xu
  • Publisher : World Scientific
  • Release : 28 July 2016
GET THIS BOOKPerspectives in Micro- and Nanotechnology for Biomedical Applications

Perspectives in Micro- and Nanotechnology for Biomedical Applications is an exciting new book that takes readers inside the fast-paced world of biomedical sciences fueled by advancements in nanotechnology, polymer chemistry and pharmacology. Guided by biotech researchers Chenjie Xu and Juliana Chan, an international ensemble of leading experts in the field cover topics ranging from classical chemical tools to nanoparticles as imaging probes and drug carriers, and combinatorial screens for new lipids and polymers. At the microscale it discusses advancements in


Nanomaterials for Drug Delivery and Therapy

Nanomaterials for Drug Delivery and Therapy
  • Author : Alexandru Mihai Grumezescu
  • Publisher : William Andrew
  • Release : 14 March 2019
GET THIS BOOKNanomaterials for Drug Delivery and Therapy

Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug


Polymeric Gene Delivery Systems

Polymeric Gene Delivery Systems
  • Author : Yiyun Cheng
  • Publisher : Springer
  • Release : 04 September 2018
GET THIS BOOKPolymeric Gene Delivery Systems

​The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific


Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids
  • Author : Surendra Nimesh,Ramesh Chandra,Nidhi Gupta
  • Publisher : Woodhead Publishing
  • Release : 04 April 2017
GET THIS BOOKAdvances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles


Application of Nanotechnology in Drug Delivery

Application of Nanotechnology in Drug Delivery
  • Author : Ali Demir Sezer
  • Publisher : BoD – Books on Demand
  • Release : 25 July 2014
GET THIS BOOKApplication of Nanotechnology in Drug Delivery

This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the


Synthetic DNA Delivery Systems

Synthetic DNA Delivery Systems
  • Author : Dan Luo,W. Mark Saltzman
  • Publisher : Springer Science & Business Media
  • Release : 30 September 2003
GET THIS BOOKSynthetic DNA Delivery Systems

DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function. Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest. Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides


Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering

Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering
  • Author : Ashutosh Tiwari,Atul Tiwari
  • Publisher : John Wiley & Sons
  • Release : 19 February 2013
GET THIS BOOKNanomaterials in Drug Delivery, Imaging, and Tissue Engineering

This groundbreaking, multidisciplinary work is one of the first books to cover Nanotheragnostics, the new developmental edge of nanomedicine. Through a collection of authoritative chapters, the book reports on nanoscopic therapeutic systems that incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities. An invaluable reference for researchers in materials science, bioengineering, pharmacy, biotechnology, and nanotechnology, this volume features four main parts on biomedical nanomaterials, advanced nanomedicine, nanotheragnostics, and nanoscaffolds technology.