• Home
  • Practical Process Research and Development

Practical Process Research and Development

Practical Process Research and Development
  • Author : Neal G. Anderson
  • Publsiher : Academic Press
  • Release : 26 February 2021
  • ISBN : 0123865379
  • Pages : 475 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKPractical Process Research and Development

Summary:
Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights: • Reflects the current thinking in chemical process R&D for small molecules • Retains similar structure and orientation to the first edition. • Contains approx. 85% new material • Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up) • Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes) • Replaces the first edition, although the first edition contains useful older examples that readers may refer to Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more Presents guidelines for implementing and troubleshooting processes


Practical Process Research and Development

Practical Process Research and Development
  • Author : Neal G. Anderson
  • Publisher : Academic Press
  • Release : 26 February 2021
GET THIS BOOKPractical Process Research and Development

Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights: • Reflects the current thinking in chemical process R&D for small


Practical Process Research and Development

Practical Process Research and Development
  • Author : Neal G. Anderson
  • Publisher : Taylor & Francis US
  • Release : 03 April 2000
GET THIS BOOKPractical Process Research and Development

Foreword by K. Barry Sharpless. Foreword by Jerome L. Moniot. Preface. About the Author. Approaches to Process Development. Route Selection. Reagent Selection. Solvent Selection. Running the Reaction. Effects of Water. In-Process Controls. Optimizing the Reaction by Minimizing Impurities. Optimizing Catalytic Reactions. Work-Up. Tools for Purifying the Product: Column Chromatography, Crystallization, and Reslurrying. Final Product Form and Impurity Considerations. Vessels and Mixing. Preparing for and Implementing the Scale-up Run. Troubleshooting. Chiral Syntheses. General Index. Reaction Type Index. Reagent Index.


Research for Development

Research for Development
  • Author : Sophie Laws
  • Publisher : SAGE
  • Release : 25 June 2003
GET THIS BOOKResearch for Development

`[Research for Development] is well-written and, at every stage, is well-documented with practical examples. The simplicity with which it is written adds to its value in that non-professional persons get well-aquainted with the research process. Every chapter in the book ends with highlighting of the main points made in that chapter... A further strength of the book is the inclusion of an appendix with a list of websites that deal with issues in the area of development research... the simplicity


Proceedings of the Scientific-Practical Conference "Research and Development - 2016"

Proceedings of the Scientific-Practical Conference
  • Author : K. V. Anisimov,A. V. Dub,S. K. Kolpakov,A. V. Lisitsa,A. N. Petrov,V. P. Polukarov,O. S. Popel,V. A. Vinokurov
  • Publisher : Springer
  • Release : 04 December 2017
GET THIS BOOKProceedings of the Scientific-Practical Conference "Research and Development - 2016"

This book is open access under a CC BY 4.0 license. It relates to the III Annual Conference hosted by The Ministry of Education and Science of the Russian Federation in December 2016. This event has summarized, analyzed and discussed the interim results, academic outputs and scientific achievements of the Russian Federal Targeted Programme “Research and Development in Priority Areas of Development of the Russian Scientific and Technological Complex for 2014–2020.” It contains 75 selected papers from 6 areas considered priority by the Federal Targeted


Practical Guide to Research and Development Tax Incentives

Practical Guide to Research and Development Tax Incentives
  • Author : Michael D. Rashkin
  • Publisher : CCH
  • Release : 26 February 2021
GET THIS BOOKPractical Guide to Research and Development Tax Incentives

CCH's Practical Guide to Research and Development Tax Incentives--Federal, State, and Foreign by Michael Rashkin, J.D., LL.M., provides something that has been missing in professional tax literature--authoritative, comprehensive coverage of this complex and evolving topic. This newly expanded resource is practical, easy to follow, easy to understand, and is particularly effective at clarifying and demystifying this complex subject. It provides well-written, detailed guidance on claiming the federal credit for increasing research activities and the deduction for R & D


Doing Developmental Research

Doing Developmental Research
  • Author : Tricia Striano
  • Publisher : Guilford Publications
  • Release : 19 February 2016
GET THIS BOOKDoing Developmental Research

"Subject Areas/Keywords: child development, children, developmental psychology, developmental research methods, developmental science, early childhood, infancy research, infants, parents, preschoolers, research laboratory, research studies DESCRIPTION Addressing practical issues rarely covered in methods texts, this userfriendly, jargonfree book helps students and beginning researchers plan infant and child development studies and get them done. The author provides stepbystep guidance for getting involved in a developmental laboratory and crafting effective research questions and proposals. Tips on recruiting study participants cover access issues--such as


Applied Research in Child and Adolescent Development

Applied Research in Child and Adolescent Development
  • Author : Valerie Maholmes,Carmela Gina Lomonaco
  • Publisher : Psychology Press
  • Release : 11 January 2011
GET THIS BOOKApplied Research in Child and Adolescent Development

Developed for an NIH training institute, this volume is organized around the most frequently asked questions by researchers starting their careers in applied research in child and adolescent development. With contributions from the leading scholars in the field, actual research experiences highlight the challenges one faces in conducting such research. The techniques and theoretical frameworks most suitable for guiding the applied research process are reviewed along with related ethical and cultural considerations. Each chapter features the authors’ introduction to their


Industrial Process Scale-up

Industrial Process Scale-up
  • Author : Jan Harmsen
  • Publisher : Elsevier
  • Release : 25 April 2013
GET THIS BOOKIndustrial Process Scale-up

This book will help industrial process innovators in research, development and commercial start-up to assess the risks of commercial-scale implementation and provide them with practical guidelines and methods to reduce the risks to acceptable levels. The book can also be used in co-operation with industrial R&D people and academic researchers to shape open innovation programs and in education as a reference book for process innovation courses. Offers easily accessible, step-by-step, and concise guidelines for industrial process scale-up Explains each


Fishery Co-Management

Fishery Co-Management
  • Author : Robert S. Pomeroy,Rebecca Rivera-Guieb
  • Publisher : CABI
  • Release : 26 February 2021
GET THIS BOOKFishery Co-Management

During the last decade, there has been a shift in the governance and management of fisheries to a broaderapproach that recognizes the participation of fishers, local stewardship, and shared decision-making.Through this process, fishers are empowered to become active members of the management team,balancing rights and responsibilities, and working in partnership with government. This approach iscalled co-management.This handbook describes the process of community-based co-management from its beginning, throughimplementation, to turnover to the community. It provides ideas, methods, techniques,


Overseas Research

Overseas Research
  • Author : Christopher B. Barrett,Jeffrey Cason,Erin C. Lentz
  • Publisher : Routledge
  • Release : 31 March 2020
GET THIS BOOKOverseas Research

When conducting research in developing countries, an ability to negotiate a bewildering array of cultural and logistical obstacles is essential. Overseas Research: A Practical Guide distills essential lessons from scores of students and scholars who have collected data and done fieldwork abroad, including how to prepare for the field, how and where to find funding for one’s fieldwork, issues of personal safety and security, and myriad logistical and relational issues. By encouraging researchers to think through the challenges of


Dealing With Complexity in Development Evaluation

Dealing With Complexity in Development Evaluation
  • Author : Michael Bamberger,Jos Vaessen,Estelle Raimondo
  • Publisher : SAGE Publications
  • Release : 16 October 2015
GET THIS BOOKDealing With Complexity in Development Evaluation

Recognizing that complexity calls for innovative, conceptual, and methodological solutions, Dealing with Complexity in Development Evaluation by Michael Bamberger, Jos Vaessen, and Estelle Raimondo offers practical guidance to policymakers, managers, and evaluation practitioners on how to design and implement complexity-responsive evaluations that can be undertaken in the real world of time, budget, data, and political constraints. Introductory chapters present comprehensive, non-technical overviews of the most common evaluation tools and methodologies, and additional content addresses more cutting-edge material. The book also


Process Chemistry in the Pharmaceutical Industry

Process Chemistry in the Pharmaceutical Industry
  • Author : Kumar Gadamasetti
  • Publisher : CRC Press
  • Release : 06 May 1999
GET THIS BOOKProcess Chemistry in the Pharmaceutical Industry

Providing guidance for chemists and other scientists entering pharmaceutical discovery and development, this up-to-the-minute reference presents contributions from an international group of nearly 50 renowned researchers—offering a solid grounding in synthetic and physical organic chemistry, and clarifying the roles of various specialties in the development of new drugs. Featuring over 1000 references, tables, and illustrations, Process Chemistry in the Pharmaceutical Industry is sure to find its way to the bookshelves of organic, physical, analytical, process, and medicinal chemists and biochemists; pharmacists;


Medical Writing in Drug Development

Medical Writing in Drug Development
  • Author : Robert J Bonk
  • Publisher : Routledge
  • Release : 02 January 2014
GET THIS BOOKMedical Writing in Drug Development

A guide through the maze of the pharmaceutical research and development process, Medical Writing in Drug Development fills a gap in the libraries of technical writers, college instructors, and corporate professionals associated with the pharmaceutical process. As it discusses critical information, such as strategies and techniques pivotal to crafting documents for drug development, it also overviews drug research, document types, the roles of professional writers, and information technology. In no time at all, you will be creating persuasive technical documents,


Qualitative Research for Development

Qualitative Research for Development
  • Author : Morten Skovdal,Flora Cornish
  • Publisher : Practical Action
  • Release : 15 October 2015
GET THIS BOOKQualitative Research for Development

How do we know whether our development programmes are reducing poverty and empowering the most vulnerable people? What evidence do we have to support our theory of change? Qualitative research for development aims to build the research capacity of development practitioners so that their work benefits from the significant contributions offered by solid qualitative research. The book guides development practitioners through the process of planning, conducting and reporting on a qualitative study, whilst simultaneously highlighting the role of qualitative research


A Practical Guide to Drug Development in Academia

A Practical Guide to Drug Development in Academia
  • Author : Daria Mochly-Rosen,Kevin Grimes
  • Publisher : Springer Science & Business Media
  • Release : 08 July 2014
GET THIS BOOKA Practical Guide to Drug Development in Academia

"A lot of hard-won knowledge is laid out here in a brief but informative way. Every topic is well referenced, with citations from both the primary literature and relevant resources from the internet." Review from Nature Chemical Biology Written by the founders of the SPARK program at Stanford University, this book is a practical guide designed for professors, students and clinicians at academic research institutions who are interested in learning more about the drug development process and how to help