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Precision Medicine and the Reinvention of Human Disease

Precision Medicine and the Reinvention of Human Disease
  • Author : Jules J. Berman
  • Publsiher : Academic Press
  • Release : 26 January 2018
  • ISBN : 0128143940
  • Pages : 398 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKPrecision Medicine and the Reinvention of Human Disease

Summary:
Despite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ among individuals, based on genetic and environmental conditions. We are currently developing rational therapies and preventive measures, based on our precise understanding of the steps leading to the clinical expression of diseases. Precision Medicine and the Reinvention of Human Disease explains the scientific breakthroughs that have changed the way that we understand diseases, and reveals how medical scientists are using this new knowledge to launch a medical revolution. Clarifies the foundational concepts of Precision Medicine, distinguishing this field from its predecessors such as genomics, pharmacogenetics, and personalized medicine. Gathers the chief conceptual advances in the fields of genetics, pathology, and bioinformatics, and synthesizes a coherent narrative for the field of Precision Medicine. Delivers its message in plain language, and in a relaxed, conversational writing style, making it easy to understand the complex subject matter. Guides the reader through a coherent and logical narrative, gradually providing expertise and skills along the way. Covers the importance of data sharing in Precision Medicine, and the many data-related challenges that confront this fragile new field.


Precision Medicine and the Reinvention of Human Disease

Precision Medicine and the Reinvention of Human Disease
  • Author : Jules J. Berman
  • Publisher : Academic Press
  • Release : 26 January 2018
GET THIS BOOKPrecision Medicine and the Reinvention of Human Disease

Despite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ


Taxonomic Guide to Infectious Diseases

Taxonomic Guide to Infectious Diseases
  • Author : Jules J. Berman
  • Publisher : Academic Press
  • Release : 31 May 2019
GET THIS BOOKTaxonomic Guide to Infectious Diseases

Taxonomic Guide to Infectious Diseases: Understanding the Biologic Classes of Pathogenic Organisms, Second Edition tackles the complexity of clinical microbiology by assigning every infectious organism to one of 40+ taxonomic classes and providing a description of the defining traits that apply to all the organisms within each class. This edition is an updated, revised and greatly expanded guide to the classes of organisms that infect humans. This book will provide students and clinicians alike with a simplified way to understand the


Evolution's Clinical Guidebook

Evolution's Clinical Guidebook
  • Author : Jules J. Berman
  • Publisher : Academic Press
  • Release : 25 April 2019
GET THIS BOOKEvolution's Clinical Guidebook

Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a


Logic and Critical Thinking in the Biomedical Sciences

Logic and Critical Thinking in the Biomedical Sciences
  • Author : Jules J. Berman
  • Publisher : Academic Press
  • Release : 08 July 2020
GET THIS BOOKLogic and Critical Thinking in the Biomedical Sciences

All too often, individuals engaged in the biomedical sciences assume that numeric data must be left to the proper authorities (e.g., statisticians and data analysts) who are trained to apply sophisticated mathematical algorithms to sets of data. This is a terrible mistake. Individuals with keen observational skills, regardless of their mathematical training, are in the best position to draw correct inferences from their own data and to guide the subsequent implementation of robust, mathematical analyses. Volume 2 of Logic and


Taxonomic Guide to Infectious Diseases

Taxonomic Guide to Infectious Diseases
  • Author : Jules J. Berman
  • Publisher : Academic Press
  • Release : 06 March 2021
GET THIS BOOKTaxonomic Guide to Infectious Diseases

In the past few decades, there have been great advances in the phylogenetic classification of infectious diseases of man. Taxonomic Guide to Infectious Diseases organizes this information into a standard biological classification and provides a short, clinically-oriented description of every genus (class) of infectious organism. It covers an overview of modern taxonomy, including a description of the kingdoms of life and the evolutionary principles underlying the class hierarchy, and each following chapter will describe one phylum and the genera that


Brugada Phenocopy

Brugada Phenocopy
  • Author : Adrian Baranchuk
  • Publisher : Academic Press
  • Release : 28 March 2018
GET THIS BOOKBrugada Phenocopy

Brugada Phenocopy: The Art of Recognizing the Brugada ECG Pattern details all aspects associated with alternative diagnosis to Brugada Syndrome (BrS). Coverage includes how to identify the proper ECG pattern, what to do to investigate for BrP, and how to avoid misinterpretations and the use of unnecessary and expensive treatments. Chapters are written by experienced professionals, many of whom are colleagues that initially described this condition. This easy to use volume is a must have reference for researchers of cardiology,


Principles of Big Data

Principles of Big Data
  • Author : Jules J. Berman
  • Publisher : Newnes
  • Release : 20 May 2013
GET THIS BOOKPrinciples of Big Data

Principles of Big Data helps readers avoid the common mistakes that endanger all Big Data projects. By stressing simple, fundamental concepts, this book teaches readers how to organize large volumes of complex data, and how to achieve data permanence when the content of the data is constantly changing. General methods for data verification and validation, as specifically applied to Big Data resources, are stressed throughout the book. The book demonstrates how adept analysts can find relationships among data objects held


MoneyBall Medicine

MoneyBall Medicine
  • Author : Harry Glorikian,Malorye Allison Branca
  • Publisher : Taylor & Francis
  • Release : 20 November 2017
GET THIS BOOKMoneyBall Medicine

How can a smartwatch help patients with diabetes manage their disease? Why can’t patients find out prices for surgeries and other procedures before they happen? How can researchers speed up the decade-long process of drug development? How will "Precision Medicine" impact patient care outside of cancer? What can doctors, hospitals, and health systems do to ensure they are maximizing high-value care? How can healthcare entrepreneurs find success in this data-driven market? A revolution is transforming the $10 trillion healthcare landscape,


Logic and Critical Thinking in the Biomedical Sciences

Logic and Critical Thinking in the Biomedical Sciences
  • Author : Jules J. Berman
  • Publisher : Academic Press
  • Release : 03 July 2020
GET THIS BOOKLogic and Critical Thinking in the Biomedical Sciences

Science is not a collection of facts. Science is the process by which we draw inferences from facts. Volume I of Logic and Critical Thinking in the Biomedical Sciences invites readers to linger over a collection of common observations to see what inferences can be drawn, when one applies a bit of deductive logic. If we just think about what we observe, it is often possible to discover profound biomedical insights. Volumes 1 and 2 of Logic and Critical Thinking in the


Precision Medicine

Precision Medicine
  • Author : Hans-Peter Deigner,Matthias Kohl
  • Publisher : Academic Press
  • Release : 15 February 2018
GET THIS BOOKPrecision Medicine

Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for


Network Medicine

Network Medicine
  • Author : Joseph Loscalzo
  • Publisher : Harvard University Press
  • Release : 01 February 2017
GET THIS BOOKNetwork Medicine

Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. With contributions from leading experts, Network Medicine introduces this rapidly evolving field of research, which promises to revolutionize the diagnosis and treatment of human diseases.


One in a Billion

One in a Billion
  • Author : Mark Johnson,Kathleen Gallagher
  • Publisher : Simon and Schuster
  • Release : 12 April 2016
GET THIS BOOKOne in a Billion

Pulitzer Prize-winning journalists Mark Johnson and Kathleen Gallagher chronicle the story of Nic Volker, the Wisconsin boy at the center of a daring breakthrough in medicine--a complete gene sequencing to discover the cure for an otherwise undiagnosable illness. At just two years old, Nic experienced a searing pain that signaled the awakening of a new and deadly disease. For years, through false starts and failed cures, Nic holds on to life, buoyed up by his mother's fierce drive to get


Graphic Medicine Manifesto

Graphic Medicine Manifesto
  • Author : MK Czerwiec,Ian Williams,Susan Merrill Squier,Michael J. Green,Kimberly R. Myers,Scott T. Smith
  • Publisher : Penn State Press
  • Release : 13 May 2015
GET THIS BOOKGraphic Medicine Manifesto

This inaugural volume in the Graphic Medicine series establishes the principles of graphic medicine and begins to map the field. The volume combines scholarly essays by members of the editorial team with previously unpublished visual narratives by Ian Williams and MK Czerwiec, and it includes arresting visual work from a wide range of graphic medicine practitioners. The book’s first section, featuring essays by Scott Smith and Susan Squier, argues that as a new area of scholarship, research on graphic


Eros and Illness

Eros and Illness
  • Author : David B. Morris
  • Publisher : Harvard University Press
  • Release : 27 February 2017
GET THIS BOOKEros and Illness

When we or our loved ones fall ill, our world is thrown into disarray, our routines are interrupted, our beliefs shaken. David Morris offers an unconventional, deeply human exploration of what it means to live with, and live through, disease. He shows how desire—emotions, dreams, stories, romance, even eroticism—plays a crucial part in illness.


The Gene, the Clinic, and the Family

The Gene, the Clinic, and the Family
  • Author : Joanna Latimer
  • Publisher : Routledge
  • Release : 04 July 2013
GET THIS BOOKThe Gene, the Clinic, and the Family

While some theorists argue that medicine is caught in a relentless process of ‘geneticization’ and others offer a thesis of biomedicalization, there is still little research that explores how these effects are accomplished in practice. Joanna Latimer, whose groundbreaking ethnography on acute medicine gave us the social science classic The Conduct of Care, moves her focus from the bedside to the clinic in this in-depth study of genetic medicine. Against current thinking that proselytises the rise of laboratory science, Professor