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Principles of Nucleic Acid Structure

Principles of Nucleic Acid Structure
  • Author : Stephen Neidle
  • Publsiher : Elsevier
  • Release : 26 July 2010
  • ISBN : 9780080553528
  • Pages : 302 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKPrinciples of Nucleic Acid Structure

Summary:
This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, Principles of Nucleic Acid Structure includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software. Completely updated with expanded discussion of topics such as RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA) Includes a complete list of resources, including relevant online databases and software Defines technical lingo for novices


Principles of Nucleic Acid Structure

Principles of Nucleic Acid Structure
  • Author : Stephen Neidle
  • Publisher : Elsevier
  • Release : 26 July 2010
GET THIS BOOKPrinciples of Nucleic Acid Structure

This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, Principles of Nucleic Acid Structure includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features



Nucleic Acid Structure and Recognition

Nucleic Acid Structure and Recognition
  • Author : Cancer Research Campaign Biomolecular Structure Unit Stephen Neidle,Stephen Neidle
  • Publisher : Oxford University Press, USA
  • Release : 26 February 2021
GET THIS BOOKNucleic Acid Structure and Recognition

This book provides a detailed view of the molecular structures of DNA and RNA and how they are recognised by small molecules and proteins. Extensive source material is provided, including information on relevant web sites and computer programmes. The major methods of structural investigationfor nucleic acids: X-ray crystallography, NMR, and molecular modelling are reviewed and their scope and limitations (in the context of nucleic acids) discussed. Also covered are the conformational features of nucleic acid building blocks, including a description



Diagnostic Molecular Biology

Diagnostic Molecular Biology
  • Author : Chang-Hui Shen
  • Publisher : Academic Press
  • Release : 02 April 2019
GET THIS BOOKDiagnostic Molecular Biology

Diagnostic Molecular Biology describes the fundamentals of molecular biology in a clear, concise manner to aid in the comprehension of this complex subject. Each technique described in this book is explained within its conceptual framework to enhance understanding. The targeted approach covers the principles of molecular biology including the basic knowledge of nucleic acids, proteins, and genomes as well as the basic techniques and instrumentations that are often used in the field of molecular biology with detailed procedures and explanations.


Molecular Diagnostics

Molecular Diagnostics
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher : Springer Science & Business Media
  • Release : 18 April 2013
GET THIS BOOKMolecular Diagnostics

Notable practitioners describe how laboratory medicine is practiced today and illuminate how it will function tomorrow as the revolutionary advances afforded by molecular diagnostics become increasingly central to effective analysis. Proceeding from a discussion of elementary nucleic acid technology to a review of the more advanced techniques, the distinguished contributors lay the groundwork for a comprehensive understanding of their applications throughout clinical medicine. The result is a detailed description of those molecular technologies currently used in diagnostic laboratories, as well


Nucleic Acids in Chemistry and Biology

Nucleic Acids in Chemistry and Biology
  • Author : G. Michael Blackburn,Michael J. Gait
  • Publisher : Irl Press
  • Release : 26 February 1996
GET THIS BOOKNucleic Acids in Chemistry and Biology

Since the discovery of the DNA double helix in 1953, nucleic acids have formed the central theme of much of contemporary molecular science. Nowhere is this more apparent than in the increasing efforts to determine the DNA sequence of the human genome and the development of new diagnostics of genetic disease. Recent sophistication of nucleic acids synthesis has been key to the establishment of the biotechnology industry and our improving knowledge of nucleic acid structures and interactions is noticeably influencing the




Protein-Nucleic Acid Interactions

Protein-Nucleic Acid Interactions
  • Author : Phoebe A. Rice,Carl C. Correll
  • Publisher : Royal Society of Chemistry
  • Release : 22 May 2008
GET THIS BOOKProtein-Nucleic Acid Interactions

The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid 1980s and a vast array of such structures has now been determined, but surprising and novel structures still appear quite frequently. High-resolution structures of protein-RNA complexes were relatively rare until the last decade. Propelled by advances in technology as well as the realization of RNA's importance to biology, the


Nucleic Acid Structure

Nucleic Acid Structure
  • Author : W. Guschlbauer
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKNucleic Acid Structure

Teaching a course on nucleic acid structure is a hazardous undertaking, especially if one has no continuous teaching obligations. I still have done it on several occasions in various French universities, when colleagues, suffering from admin istrative overwork and excessive teaching obligations, had asked me to do so. This was generally done with a pile of notes and a dozen slides, and I always regretted that no small, concise, specialized book on nucleic acid structure for students at the senior


Handbook of Nucleic Acid Purification

Handbook of Nucleic Acid Purification
  • Author : Dongyou Liu
  • Publisher : CRC Press
  • Release : 14 January 2009
GET THIS BOOKHandbook of Nucleic Acid Purification

An Indispensable Roadmap for Nucleic Acid Preparation Although Friedrich Miescher described the first isolation of nucleic acid in 1869, it was not until 1953 that James Watson and Francis Crick successfully deciphered the structural basis of DNA duplex. Needless to say, in the years since, enormous advances have been made in the study of nucleic acids, and these have become a cornerstone for all branches of modern biological sciences. The Handbook of Nucleic Acid Purification provides researchers and students with an all-encompassing



The Molecules of Life

The Molecules of Life
  • Author : Kuriyan, John,Konforti, Boyana,Wemmer, David
  • Publisher : W.W. Norton & Company
  • Release : 25 July 2012
GET THIS BOOKThe Molecules of Life

This textbook provides an integrated physical and biochemical foundation for undergraduate students majoring in biology or health sciences. It is particularly suitable for students planning to enter the pharmaceutical industry. This new generation of molecular biologists and biochemists will harness the tools and insights of physics and chemistry to exploit the emergence of genomics and systems-level information in biology, and will shape the future of medicine.


Nucleic Acids

Nucleic Acids
  • Author : Marcelo Larramendy,Sonia Soloneski
  • Publisher : BoD – Books on Demand
  • Release : 16 March 2016
GET THIS BOOKNucleic Acids

This edited book, "Nucleic Acids - From Basic Aspects to Laboratory Tools", contains a series of chapters that highlight the development and status of the various aspects of the nucleic acids related to DNA chemistry and biology and the molecular application of these small DNA molecules and related synthetic analogues within biological systems. Furthermore, it is hoped that the information in the present book will be of value to those directly engaged in the handling and use of nucleic acids,