• Home
  • Proteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery
  • Author : Haleem J. Issaq
  • Publsiher : Academic Press
  • Release : 24 October 2019
  • ISBN : 0128197889
  • Pages : 504 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKProteomic and Metabolomic Approaches to Biomarker Discovery

Summary:
Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. This second edition has been fully updated and revised to address recent advances in MS and NMR instrumentation, high-field NMR, proteomics and metabolomics for biomarker validation, clinical assays of biomarkers and clinical MS and NMR, identifying microRNAs and autoantibodies as biomarkers, MRM-MS assay development, top-down MS, glycosylation-based serum biomarkers, cell surface proteins in biomarker discovery, lipodomics for cancer biomarker discovery, and strategies to design studies to identify predictive biomarkers in cancer research. Addresses the full range of proteomic and metabolomic methods and technologies used for biomarker discovery and validation Covers all steps involved in biomarker discovery, from study design to study execution Serves as a vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals and graduate students


Proteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery
  • Author : Haleem J. Issaq,Timothy D. Veenstra
  • Publisher : Academic Press
  • Release : 24 October 2019
GET THIS BOOKProteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques

Book Proteomic and Metabolomic Approaches to Biomarker Discovery PDF Download/ Read Online


The Detection of Biomarkers

The Detection of Biomarkers
  • Author : Sibel A. Ozkan,Nurgul K. Bakirhan,Fariba Mollaraosouli
  • Publisher : Academic Press
  • Release : 05 December 2021
GET THIS BOOKThe Detection of Biomarkers

Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple,

Book The Detection of Biomarkers PDF Download/ Read Online


Low-Abundance Proteome Discovery

Low-Abundance Proteome Discovery
  • Author : Egisto Boschetti,Pier Giorgio Righetti
  • Publisher : Newnes
  • Release : 26 March 2013
GET THIS BOOKLow-Abundance Proteome Discovery

Low-Abundance Proteome Discovery addresses the most critical challenge in biomarker discovery and progress: the identification of low-abundance proteins. The book describes an original strategy developed by the authors that permits the detection of protein species typically found in very low abundance and that may yield valuable clues to future discoveries. Known as combinatorial peptide ligand libraries, these new methodologies are one of the hottest topics related to the study of proteomics and have applications in medical diagnostics, food quality, and

Book Low-Abundance Proteome Discovery PDF Download/ Read Online


Linkers in Biomacromolecules

Linkers in Biomacromolecules
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 20 January 2021
GET THIS BOOKLinkers in Biomacromolecules

Linkers in Biomacromolecules, Volume 647 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New sections in this updated release include chapters devoted to ser-gly linkers + models, sergGly- EAAAK linkers, Effect of crowding on linker behavior, Protathether. Experimental approach to quickly test different linkers in fusion proteins, Linkers in enzyme fusions/cascade catalysis, Linker dependence of avidity in multivalent interactions between disordered proteins, ER/K a-helix linker, The

Book Linkers in Biomacromolecules PDF Download/ Read Online


Bioinformatics in Rice Research

Bioinformatics in Rice Research
  • Author : Manoj Kumar Gupta,Lambodar Behera
  • Publisher : Springer Nature
  • Release : 24 September 2021
GET THIS BOOKBioinformatics in Rice Research

This book provides an up-to-date review of classic and advanced bioinformatics approaches and their utility in rice research. It summarizes databases and tools for analyzing DNA, proteins and gene expression profiles, mapping genetic variations, annotation of protein and RNA molecules, phylogenetic analysis, and pathway enrichment. In addition, it presents high-throughput technologies that are widely used to provide deep insights into the genetic architecture of important traits in the rice genome. The book subsequently discusses techniques for identifying RNA-protein, DNA-protein interactions,

Book Bioinformatics in Rice Research PDF Download/ Read Online


Nutrition in the Prevention and Treatment of Disease

Nutrition in the Prevention and Treatment of Disease
  • Author : Ann M. Coulston,Carol J. Boushey,Mario Ferruzzi,Linda Delahanty
  • Publisher : Academic Press
  • Release : 28 April 2017
GET THIS BOOKNutrition in the Prevention and Treatment of Disease

Nutrition in the Prevention and Treatment of Disease, Fourth Edition, is a compilation of current knowledge in clinical nutrition and an overview of the rationale and science base of its application to practice in the prevention and treatment of disease. In its fourth edition, this text continues the tradition of incorporating new discoveries and methods related to this important area of research Generating and analyzing data that summarize dietary intake and its association with disease are valuable tasks in treating

Book Nutrition in the Prevention and Treatment of Disease PDF Download/ Read Online


Proteomics for Biological Discovery

Proteomics for Biological Discovery
  • Author : Timothy D. Veenstra,John R. Yates, III
  • Publisher : John Wiley & Sons
  • Release : 07 May 2019
GET THIS BOOKProteomics for Biological Discovery

An update to the popular guide to proteomics technology applications in biomedical research Building on the strength of the original edition, this book presents the state of the art in the field of proteomics and offers students and scientists new tools and techniques to advance their own research. Written by leading experts in the field, it provides readers with an understanding of new and emerging directions for proteomics research and applications. Proteomics for Biological Discovery begins by discussing the emergence

Book Proteomics for Biological Discovery PDF Download/ Read Online


Bioinformatics and Biomarker Discovery

Bioinformatics and Biomarker Discovery
  • Author : Francisco Azuaje
  • Publisher : John Wiley & Sons
  • Release : 24 August 2011
GET THIS BOOKBioinformatics and Biomarker Discovery

This book is designed to introduce biologists, clinicians and computational researchers to fundamental data analysis principles, techniques and tools for supporting the discovery of biomarkers and the implementation of diagnostic/prognostic systems. The focus of the book is on how fundamental statistical and data mining approaches can support biomarker discovery and evaluation, emphasising applications based on different types of "omic" data. The book also discusses design factors, requirements and techniques for disease screening, diagnostic and prognostic applications. Readers are provided

Book Bioinformatics and Biomarker Discovery PDF Download/ Read Online


HPLC and UHPLC for Practicing Scientists

HPLC and UHPLC for Practicing Scientists
  • Author : Michael W. Dong
  • Publisher : John Wiley & Sons
  • Release : 10 July 2019
GET THIS BOOKHPLC and UHPLC for Practicing Scientists

A concise yet comprehensive reference guide on HPLC/UHPLC that focuses on its fundamentals, latest developments, and best practices in the pharmaceutical and biotechnology industries Written for practitioners by an expert practitioner, this new edition of HPLC and UHPLC for Practicing Scientists adds numerous updates to its coverage of high-performance liquid chromatography, including comprehensive information on UHPLC (ultra-high-pressure liquid chromatography) and the continuing migration of HPLC to UHPLC, the modern standard platform. In addition to introducing readers to HPLC’s

Book HPLC and UHPLC for Practicing Scientists PDF Download/ Read Online


Chemometrics and Data Analysis in Chromatography

Chemometrics and Data Analysis in Chromatography
  • Author : Vu Dang Hoang
  • Publisher : Anonim
  • Release : 20 March 2019
GET THIS BOOKChemometrics and Data Analysis in Chromatography

Chromatography approaches are widely used in various life science applications. Since its invention by the Russian botanist Mikhail S. Tsvet in 1901, chromatography has increasingly developed into an invaluable laboratory tool for the separation and identification of chemical components. It outperforms older techniques (such as crystallization, solvent extraction, and distillation) by offering unequaled resolving power and the possibility of lowering detection limits to below nanogram levels. To further improve chromatographic methods, however, the use of chemometrics is advisable as an economical

Book Chemometrics and Data Analysis in Chromatography PDF Download/ Read Online


Advanced Mass Spectrometry-based Analytical Separation Techniques for Probing the Polar Metabolome

Advanced Mass Spectrometry-based Analytical Separation Techniques for Probing the Polar Metabolome
  • Author : Rawi Ramautar
  • Publisher : Royal Society of Chemistry
  • Release : 13 July 2021
GET THIS BOOKAdvanced Mass Spectrometry-based Analytical Separation Techniques for Probing the Polar Metabolome

The efficient analysis of polar and charged metabolites in biological samples remains a huge challenge in the field of metabolomics. Over the past years, novel mass spectrometry-based analytical tools have been developed to enable the sensitive and efficient profiling of polar ionogenic metabolites in various biological samples. This book gives the reader a comprehensive overview of these recent technological developments. Topics covered include the use of chemical labelling strategies for allowing the analysis of polar metabolites using reversed-phase liquid chromatography–

Book Advanced Mass Spectrometry-based Analytical Separation Techniques for Probing the Polar Metabolome PDF Download/ Read Online


Immunohistochemistry

Immunohistochemistry
  • Author : Charles Streckfus
  • Publisher : BoD – Books on Demand
  • Release : 04 March 2020
GET THIS BOOKImmunohistochemistry

Immunohistochemistry - The Ageless Biotechnology is a book that is ideal for undergraduate and graduate biomedical researchers, and medical and dental health professionals. It is a detailed text, which emphasizes the laboratory and clinical implications of immunohistochemistry. The text covers the advances of immunohistochemistry from its humble origins in the 1930s up to the new decade of 2020. The book also offers a review of the immunohistochemistry detection systems with emphasis on their principles, history, and their advantages. It also stipulates

Book Immunohistochemistry PDF Download/ Read Online


Environmental Metabolomics

Environmental Metabolomics
  • Author : Diana Alvarez-Munoz,Marinella Farre
  • Publisher : Elsevier
  • Release : 19 May 2020
GET THIS BOOKEnvironmental Metabolomics

Environmental Metabolomics Applications in Field and Laboratory Studies: From the Exposome to the Metabolome presents an overview of the current state of aquatic environments and problems caused by human pressure and daily life. The presence of contaminants in nature and their effects are evaluated, along with recommendations for preservation. This book not only shows readers how to implement techniques, it also guides them through the process. As metabolomics becomes a more routine technique for environmental studies and future perspectives, a

Book Environmental Metabolomics PDF Download/ Read Online


Metabolomics for Biomedical Research

Metabolomics for Biomedical Research
  • Author : Jerzy Adamski
  • Publisher : Academic Press
  • Release : 20 March 2020
GET THIS BOOKMetabolomics for Biomedical Research

Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research. Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects. The book discusses topics such as biomarkers and their requirements to be used in medical research, with the parameters and approaches on how to validate their quality; and animal models and other approaches, as stem cells

Book Metabolomics for Biomedical Research PDF Download/ Read Online


Cancer Metabolomics

Cancer Metabolomics
  • Author : Shen Hu
  • Publisher : Springer Nature
  • Release : 03 May 2021
GET THIS BOOKCancer Metabolomics

Cancer metabolomics is a rapidly evolving field that aims for a comprehensive dissection of the metabolic phenotypes and functional network of metabolites in human cancers. State of the art metabolomics tools have been developed and applied to studying cancer metabolism and developing metabolic targets for improved diagnosis, prognosis and therapeutic treatment of human cancers. Chapters are written by subject experts in the field of cancer metabolomics with cross-disciplinary contributions. Coverage includes advanced metabolomics technologies and methodologies, including chemical isotope labelling

Book Cancer Metabolomics PDF Download/ Read Online