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Reactive Oxygen Species ROS Nanoparticles and Endoplasmic Reticulum ER Stress Induced Cell Death Mechanisms

Reactive Oxygen Species  ROS   Nanoparticles  and Endoplasmic Reticulum  ER  Stress Induced Cell Death Mechanisms
  • Author : Loutfy H. Madkour
  • Publsiher : Academic Press
  • Release : 27 June 2020
  • ISBN : 0128224967
  • Pages : 780 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKReactive Oxygen Species ROS Nanoparticles and Endoplasmic Reticulum ER Stress Induced Cell Death Mechanisms

Summary:
Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences. Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment


Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms

Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and

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Nanoparticle-Based Drug Delivery in Cancer Treatment

Nanoparticle-Based Drug Delivery in Cancer Treatment
  • Author : Loutfy H. Madkour
  • Publisher : CRC Press
  • Release : 03 March 2022
GET THIS BOOKNanoparticle-Based Drug Delivery in Cancer Treatment

The careful choice of nanoparticles as targets and in drug delivery routes enhances therapeutic efficacy in cancer. Nanoparticle-Based Drug Delivery in Cancer Treatment discusses nanotechnological developments of interfering RNA-based nanoparticles, delivery vehicles, and validated therapeutic RNAi–molecular target interactions and explains the results of clinical and preclinical trials. The book also gives strategies for universal methods of constructing hybrid organic–inorganic nanomaterials that can be widely applied in the biomedical field. Key Features: Reviews recent advances of nanoparticle-mediated siRNA delivery

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RNA Delivery Function for Anticancer Therapeutics

RNA Delivery Function for Anticancer Therapeutics
  • Author : Loutfy H. Madkour
  • Publisher : CRC Press
  • Release : 26 January 2022
GET THIS BOOKRNA Delivery Function for Anticancer Therapeutics

This book presents an overview of the current status of translating the RNAi cancer therapeutics in the clinic, a brief description of the biological barriers in drug delivery, and the roles of imaging in aspects of administration route, systemic circulation, and cellular barriers for the clinical translation of RNAi cancer therapeutics, and with partial content for discussing the safety concerns. It then focuses on imaging-guided delivery of RNAi therapeutics in preclinical development, including the basic principles of different imaging modalities,

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Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses

Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses
  • Author : Loutfy H. Madkour
  • Publisher : Anonim
  • Release : 27 June 2022
GET THIS BOOKNanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses

This book provides insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. It presents the recent advances in new nanomedication technologies of the effects of nanoparticles NPs on oxidative stress, RONS and ER stress. The book comprises 13 chapters covering ecotoxicology, cytotoxicity, nanotoxicity and genotoxicity mechanisms causing by the role and interactions of nanoparticles and free radicals with (RONS) and (ER) stress.

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Emerging Nanomaterials for Advanced Technologies

Emerging Nanomaterials for Advanced Technologies
  • Author : Anand Krishnan
  • Publisher : Springer Nature
  • Release : 27 June 2022
GET THIS BOOKEmerging Nanomaterials for Advanced Technologies

Over the past decade the world has seen the rise of the fascinating and diverse field currently recognized as nanotechnology. This book covers a broad spectrum of topics within nanotechnology, including synthesis techniques, various innovative characterization techniques, growth mechanisms of nanomaterials, the physics and chemistry of nanomaterials, diverse functionalization methods, and the various applications of nanomaterials in biology, therapeutics, energy, food science, and environmental science. It also discusses applications of nanostructured materials, integrative applications such as nano- and micro-electronic sensor

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Immunity and Tolerance

Immunity and Tolerance
  • Author : Anne O'Garra,Michel Nussenzweig,Stephen T. Smale,David Johnston Stewart,Bruce Stillman
  • Publisher : Cold Spring Harbor Symposia on
  • Release : 27 June 2022
GET THIS BOOKImmunity and Tolerance

"The first time I went to the United States was in 1953...to the Cold Spring Harbor symposium where Jim Watson described in detail his model of double helix. All these symposia were extremely important. I think Cold Spring Harbor was one of the birthplaces of molecular biology" - Francois Jacob The Symposia have been one of the great institutions of such research for over 70 years and the history of whole fields can be found in the pages of the Symposia

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Ultraviolet Light in Human Health, Diseases and Environment

Ultraviolet Light in Human Health, Diseases and Environment
  • Author : Shamim I. Ahmad
  • Publisher : Springer
  • Release : 08 November 2017
GET THIS BOOKUltraviolet Light in Human Health, Diseases and Environment

This book is about the roles and importance of Ultraviolet (UV) light from sun and from man-made UV lamps in our daily life, on health and diseases, also its application in sterilization and treatment. The key words are: reactive oxygen species, DNA damage, UV mutagenicity, skin cancers, polymorphous light eruption, Xeroderma pigmentosum, vitiligo, psoriasis, rheumatoid arthritis, diabetes mellitus, metabolic syndromes, cardiovascular diseases, dermatology, photobiology, photodermatosis, vitamin D synthesis, vitamin D efficiency, water sterilization, blood sterilization, phototherapies, skin tanning and UV

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Oxidative Stress in Heart Diseases

Oxidative Stress in Heart Diseases
  • Author : Sajal Chakraborti,Naranjan S Dhalla,Nirmal K Ganguly,Madhu Dikshit
  • Publisher : Springer Nature
  • Release : 06 November 2019
GET THIS BOOKOxidative Stress in Heart Diseases

This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the

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Plant Programmed Cell Death

Plant Programmed Cell Death
  • Author : Arunika N. Gunawardena,Paul F. McCabe
  • Publisher : Springer
  • Release : 08 October 2015
GET THIS BOOKPlant Programmed Cell Death

Programmed cell death (PCD) is a genetically encoded, active process which results in the death of individual cells, tissues, or whole organs. PCD plays an essential role in plant development and defense, and occurs throughout a plant’s lifecycle from the death of the embryonic suspensor to leaf and floral organ senescence. In plant biology, PCD is a relatively new research area, however, as its fundamental importance is further recognized, publications in the area are beginning to increase significantly. The

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Interaction of Nanomaterials with the Immune System

Interaction of Nanomaterials with the Immune System
  • Author : James C. Bonner,Jared M. Brown
  • Publisher : Springer Nature
  • Release : 30 January 2020
GET THIS BOOKInteraction of Nanomaterials with the Immune System

This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immune responses such as complement activation to changes in adaptive immunity that influence pathogen responses and promote disease states such as asthma. Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs

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Current Understanding of Apoptosis

Current Understanding of Apoptosis
  • Author : Yusuf Tutar,Lutfi Tutar
  • Publisher : BoD – Books on Demand
  • Release : 29 August 2018
GET THIS BOOKCurrent Understanding of Apoptosis

Apoptosis is an essential biochemical process in cell turnover, development, and chemical-induced cell death. Current knowledge and ongoing research of apoptosis highlight our understanding in designing the therapeutic approaches for several diseases. This book covers four main sections: "Apoptosis and Necrosis," "Apoptosis Inducers," "Proteasome and Signaling Pathways in Apoptosis," and "Radiation-Based Apoptosis." The first section implicitly describes the differences between apoptosis and necrosis processes. The following section elaborates the small molecule-induced apoptosis. Then, the third section deals with proteasome and

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Mechanisms of Cell Death

Mechanisms of Cell Death
  • Author : Cell Death Society
  • Publisher : Anonim
  • Release : 27 June 1999
GET THIS BOOKMechanisms of Cell Death

As the body of research on apoptosis grows, it paradoxically becomes simpler as the principles that define the field become more flexible and inclusive. Discussions of the role of cell death in AIDS, inflammatory disease, lung and cardiac disease, and lupus each emphasize the importance of understanding and regulating inflammation and the production of apoptotic bodies. Included in these proceedings is an in-depth review of the role of death cell genes, including intriguing studies of the existence of inhibitors of

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Oxidative Damage to Plants

Oxidative Damage to Plants
  • Author : Parvaiz Ahmad
  • Publisher : Academic Press
  • Release : 29 January 2014
GET THIS BOOKOxidative Damage to Plants

With contributions that review research on this topic throughout the world, Oxidative Damage to Plants covers key areas of discovery, from the generation of reactive oxygen species (ROSs), their mechanisms, quenching of these ROSs through enzymatic and non-enzymatic antioxidants, and detailed aspects of such antioxidants as SOD and CAT. Environmental stress is responsible for the generation of oxidative stress, which causes oxidative damage to biomolecules and hence reduces crop yield. To cope up with these problems, scientists have to fully

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Nanotoxicology and Nanosafety 2.0

Nanotoxicology and Nanosafety 2.0
  • Author : Ying-Jan Wang
  • Publisher : MDPI
  • Release : 29 December 2020
GET THIS BOOKNanotoxicology and Nanosafety 2.0

With the rapid development of nanotechnology, nanomaterials have been widely applied in many industrial sectors, including medicine, consumer products, and electronics. While such technology has brought benefits and convenience to our daily lives, it may also potentially threaten human health. In some cases, nanomaterials present unexpected risks to both humans and the environment. Assessments of the potential hazards associated with nanotechnology have been emerging, but substantial challenges remain, because the large number of different nanomaterials cannot be effectively evaluated in

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