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The Chemistry and Biology of Nitroxyl HNO

The Chemistry and Biology of Nitroxyl  HNO
  • Author : Fabio Doctorovich
  • Publsiher : Elsevier
  • Release : 01 September 2016
  • ISBN : 0128011645
  • Pages : 424 pages
  • Rating : 4/5 from 21 ratings
GET THIS BOOKThe Chemistry and Biology of Nitroxyl HNO

Summary:
The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research Provides a valuable coverage of HNO’s chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule Contains high quality content from recognized experts in both industry and academia


The Chemistry and Biology of Nitroxyl (HNO)

The Chemistry and Biology of Nitroxyl (HNO)
  • Author : Fabio Doctorovich,Patrick J. Farmer,Marcelo A. Marti
  • Publisher : Elsevier
  • Release : 01 September 2016
GET THIS BOOKThe Chemistry and Biology of Nitroxyl (HNO)

The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of


Nitrosation Reactions and the Chemistry of Nitric Oxide

Nitrosation Reactions and the Chemistry of Nitric Oxide
  • Author : D.L.H. Williams
  • Publisher : Elsevier
  • Release : 16 December 2004
GET THIS BOOKNitrosation Reactions and the Chemistry of Nitric Oxide

Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until


Free Nitroxyl Radicals

Free Nitroxyl Radicals
  • Author : E. Rozantsev
  • Publisher : Springer Science & Business Media
  • Release : 14 December 2013
GET THIS BOOKFree Nitroxyl Radicals

In the short time since the first nitroxyl radical was obtained in 1959, a new branch of chemical science has arisen and taken shape-the chemistry of stable nitroxyl radicals. The present book was written by E. G. Rozantsev, one of the pioneers in this field and a prominent specialist on stable radicals at the Division of Chemical and Biological Processes of the Institute of Chemical Physics, Academy of Sciences of the USSR. His numerous papers have contributed greatly to the present


The Smallest Biomolecules: Diatomics and their Interactions with Heme Proteins

The Smallest Biomolecules: Diatomics and their Interactions with Heme Proteins
  • Author : Abhik Ghosh
  • Publisher : Elsevier
  • Release : 13 October 2011
GET THIS BOOKThe Smallest Biomolecules: Diatomics and their Interactions with Heme Proteins

This is not a book on NO biology, nor about hemoglobin, nor about heme-based sensors per se. Of course, it covers all these topics and more, but above all, it aims at providing a truly multidisciplinary perspective of heme-diatomic interactions. The overarching goal is to build bridges among disciplines, to bring about a meeting of minds. The contributors to this book hail from diverse university departments and disciplines – chemistry, biochemistry, molecular biology, microbiology, zoology, physics, medicine and surgery, bringing with


Nitrosyl Complexes in Inorganic Chemistry, Biochemistry and Medicine II

Nitrosyl Complexes in Inorganic Chemistry, Biochemistry and Medicine II
  • Author : D. Michael P. Mingos
  • Publisher : Springer
  • Release : 19 June 2014
GET THIS BOOKNitrosyl Complexes in Inorganic Chemistry, Biochemistry and Medicine II

The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures



Nitration of Hydrocarbons and Other Organic Compounds

Nitration of Hydrocarbons and Other Organic Compounds
  • Author : A. V. Topchiev
  • Publisher : Elsevier
  • Release : 22 October 2013
GET THIS BOOKNitration of Hydrocarbons and Other Organic Compounds

Nitration of Hydrocarbons and Other Organic Compounds tackles various concerns in the process of substituting hydrogen atoms in the aromatic or heterocyclic nucleus, or in saturated hydrocarbon, by nitro groups. The title first covers the nitration of aromatic and heterocyclic compounds with nitric acid and nitrating mixture, and then proceeds to discussing the mechanism of the nitration of aromatic compounds with nitric acid and nitrating mixture. Next, the selection deals with the nitration of saturated, aromatic-aliphatic and unsaturated hydrocarbons with


Redox-Active Therapeutics

Redox-Active Therapeutics
  • Author : Ines Batinić-Haberle,Júlio S. Rebouças,Ivan Spasojević
  • Publisher : Springer
  • Release : 13 October 2016
GET THIS BOOKRedox-Active Therapeutics

This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation


Pulsed Electron–Electron Double Resonance

Pulsed Electron–Electron Double Resonance
  • Author : Yuri D. Tsvetkov,Michael K. Bowman,Yuri A. Grishin
  • Publisher : Springer
  • Release : 28 December 2018
GET THIS BOOKPulsed Electron–Electron Double Resonance

This book covers the basic theory and techniques, as well as various applications of pulsed electron–electron double resonance (PELDOR or DEER). This electron paramagnetic resonance technique is able to measure the distances and the distribution of distances between electron spins in the 1.5–15 nanometer scale; to determine the geometry of spin-labeled molecules; to estimate the number of interacting spins in spin clusters; and to characterize the spatial distribution of paramagnetic centers. As a result, PELDOR is now a popular method


Handbook of Antioxidants

Handbook of Antioxidants
  • Author : Evguenii T. Denisov
  • Publisher : CRC Press
  • Release : 23 July 2019
GET THIS BOOKHandbook of Antioxidants

Designed for scientists and engineers involved in the physical chemistry of antioxidants, the Handbook of Antioxidants contains comprehensive data on the thermodynamics and reactivity of antioxidants. It includes: bond dissociation energies of antioxidants such as phenols (O-H bonds), aromatic amines (N-H bonds), hydroxyl amines (O-H bonds), thiophenols (S-H bonds) o activation energies and rate constants of reactions of peroxyl radicals with antioxidants o rate constants of reactions of phenoxyl, aminyl, and nitroxyl radicals with RH, ROOH, phenols, thiophenols, amines and



Electrochemical Reactions and Mechanisms in Organic Chemistry

Electrochemical Reactions and Mechanisms in Organic Chemistry
  • Author : J. Grimshaw
  • Publisher : Elsevier
  • Release : 01 December 2000
GET THIS BOOKElectrochemical Reactions and Mechanisms in Organic Chemistry

Electrochemical reactions make significant contributions to organic synthesis either in the laboratory or on an industrial scale. These methods have the potential for developing more "green" chemical synthesis. Over recent years, modern investigations have clarified the mechanisms of important organic electrochemical reactions. Progress has also been made in controlling the reactivity of intermediates through either radical or ionic pathways. Now is the time to gather all the electrochemical work into a textbook. As an essential addition to the armory of


Distance Measurements in Biological Systems by EPR

Distance Measurements in Biological Systems by EPR
  • Author : Lawrence Berliner,Sandra S. Eaton,Gareth R. Eaton
  • Publisher : Springer Science & Business Media
  • Release : 31 March 2001
GET THIS BOOKDistance Measurements in Biological Systems by EPR

Distance measurements in biological systems by EPR The foundation for understanding function and dynamics of biological systems is knowledge of their structure. Many experimental methodologies are used for determination of structure, each with special utility. Volumes in this series on Biological Magnetic Resonance emphasize the methods that involve magnetic resonance. This volume seeks to provide a critical evaluation of EPR methods for determining the distances between two unpaired electrons. The editors invited the authors to make this a very practical


Nitrate Esters Chemistry and Technology

Nitrate Esters Chemistry and Technology
  • Author : Jiping Liu
  • Publisher : Springer
  • Release : 06 March 2019
GET THIS BOOKNitrate Esters Chemistry and Technology

The idea of this book is to present the up-to-date research results on Nitrate Esters as explosive materials. It covers many aspects including the material structures, nitrating agent, chemical synthesis devices, preparation technology, and applications etc. In particular, this work sheds light on the comprehensive utilization and thorough destruction of the used Nitrate Easters which is crucial for preventing repeated pollution. This is a highly informative and instructive book providing insight for the researchers working on nitrating theory, energetic materials